Patents by Inventor Micael Guillot

Micael Guillot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180296479
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Application
    Filed: June 22, 2018
    Publication date: October 18, 2018
    Applicant: APRECIA PHARMACEUTICALS LLC
    Inventors: Jules JACOB, Kelly CAPUTO, Micael GUILLOT, Kenneth J. SULTZBAUGH, Thomas G. WEST
  • Patent number: 10028909
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: July 24, 2018
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Jules Jacob, Kelly Caputo, Micael Guillot, Kenneth J. Sultzbaugh, Thomas G. West
  • Publication number: 20170172919
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Application
    Filed: February 21, 2017
    Publication date: June 22, 2017
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules JACOB, Kelly CAPUTO, Micael GUILLOT, Kenneth J. SULTZBAUGH, Thomas G. WEST
  • Patent number: 9616018
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: April 11, 2017
    Assignee: Aprecia Pharmaceuticals Company
    Inventors: Jules Jacob, Kelly Caputo, Micael Guillot, Kenneth J. Sultzbaugh, Thomas G. West
  • Publication number: 20160250145
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Application
    Filed: February 17, 2016
    Publication date: September 1, 2016
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules JACOB, Kelly CAPUTO, Micael GUILLOT, Kenneth J. SULTZBAUGH, Thomas G. WEST
  • Patent number: 9314429
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: April 19, 2016
    Assignee: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules Jacob, Kelly Caputo, Micael Guillot, Kenneth J. Sultzbaugh, Thomas G. West
  • Publication number: 20150366802
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Application
    Filed: August 27, 2015
    Publication date: December 24, 2015
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules JACOB, Kelly CAPUTO, Micael GUILLOT, Kenneth J. SULTZBAUGH, Thomas G. WEST
  • Publication number: 20150030676
    Abstract: This invention relates to an oral stabilized modified release pharmaceutical dosage form containing L-methylfolate calcium, which is primarily absorbed from proximal small intestine via a saturable human proton-coupled folate transporter (h-PCFT) mediated transport intended as monotherapy for the treatment of patients with MDDs and/or diagnosed with dysthymia, schizophrenia, or degenerative dementia of the Alzheimer type.
    Type: Application
    Filed: July 29, 2014
    Publication date: January 29, 2015
    Inventors: Gopi M. VENKATESH, Micael GUILLOT, Jin-Wang LAI, Michael GOSSELIN, Nicole A. BEINBORN
  • Patent number: 7713548
    Abstract: Disclosed are amorphous solid dispersion formulations comprising 7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide.
    Type: Grant
    Filed: February 12, 2008
    Date of Patent: May 11, 2010
    Assignee: sanofi-aventis U.S. LLC
    Inventors: Irwin C. Jacobs, John D. Higgins, Micael Guillot, Nancy M. Franson, William L. Rocco, Khawla Abdullah Abu-Izza
  • Publication number: 20080160080
    Abstract: Disclosed are amorphous solid dispersion formulations comprising 7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide.
    Type: Application
    Filed: February 12, 2008
    Publication date: July 3, 2008
    Applicant: SANOFI-AVENTIS U.S. LLC
    Inventors: Irwin C. Jacobs, John D. Higgins, Micael Guillot, Nancy M. Franson, William L. Rocco, Khawla Abdullah Abu-Izza
  • Patent number: 6197787
    Abstract: A method for preparing pharmaceutical formulations of poorly soluble drug substances in the form of concentrated solutions for filling soft gelatin capsules and solid dispersions and suspensions for filling hard gelatin capsules and compressing into tablets is provided. Pharmaceutical formulations of poorly soluble drug substances are also disclosed. The formulations include the sodium salt of the poorly soluble drug substance, a conversion aid such as PEG, polysorbate, a sugar alcohol (e.g. mannitol or xylitol), propylene glycol or transcutol, and, in some cases an excipient, such as dicalcium phosphate dihydrate, lactose monohydrate, or microcrystalline cellulose.
    Type: Grant
    Filed: October 1, 1999
    Date of Patent: March 6, 2001
    Assignee: Sanofi-Synthelabo
    Inventors: Nancy M. Franson, Micael A. Guillot, Sharon M. Laughlin, William L. Rocco