Patents by Inventor Micaela Toniutti

Micaela Toniutti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for targeted immune system delivery
    Patent number: 9962448
    Abstract: Compounds and methods for targeted immune system delivery are disclosed. Pharmaceutical compositions including the disclosed compounds and a pharmaceutically acceptable excipient are also disclosed. Methods of targeted delivery to an antigen-presenting cell, and methods of treating or preventing a disease or condition susceptible to treatment by immunomodulation are disclosed.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: May 8, 2018
    Assignees: Northeastern University, National Institute of Agricultural Technology, University of Padova
    Inventors: Juan Sebastian Pappalardo, Micaela Toniutti, Stefano Salmaso, Tatyana S. Levchenko, Vladimir Torchilin
  • Compounds and Methods for Targeted Immune System Delivery
    Publication number: 20150238621
    Abstract: Compounds and methods for targeted immune system delivery are disclosed. Pharmaceutical compositions including the disclosed compounds and a pharmaceutically acceptable excipient are also disclosed. Methods of targeted delivery to an antigen-presenting cell, and methods of treating or preventing a disease or condition susceptible to treatment by immunomodulation are disclosed.
    Type: Application
    Filed: October 4, 2013
    Publication date: August 27, 2015
    Applicant: Northeastern University
    Inventors: Juan Sabastian PAPPALARDO, Micaela TONIUTTI, Stefano SALMASO, Tatyana S. LEVCHENKO, Vladimir TORCHILIN
  • Complexes of ruthenium with 2-(aminomethyl)pyridines and phosphines, their preparation and use as catalysts
    Patent number: 7638628
    Abstract: The invention relates to a new class of ruthenium (II) complexes containing as ligands 2-(aminomethyl)pyridines and phosphines, proven to be extremely active catalysts in the reduction of ketones to alcohols via hydrogen transfer. By using 2-propanol as the hydrogen source with the ruthenium complexes, high yields of the corresponding alcohol can be rapidly obtained starting from linear and cyclic alkyl aryl, dialkyl and diaryl ketones. The conversion of ketones to alcohols can reach 100% if operating in a gaseous hydrogen atmosphere (2-3 atm). Where the phosphines used are optically active, starting from prochiral ketone compounds various types of optically active alcohols can be produced, being important intermediates in the pharmaceutical industry, in the agrochemical industry and for fine chemicals generally.
    Type: Grant
    Filed: May 2, 2005
    Date of Patent: December 29, 2009
    Assignee: Universita' Degli Studi Di Udine
    Inventors: Walter Baratta, Katia Siega, Micaela Toniutti, Pierluigi Rigo
  • Complexes of Ruthenium with 2-(Aminomethyl)Pyridines and Phosphines, their Preparation and Use as Catalysts
    Publication number: 20080249308
    Abstract: The invention relates to a new class of ruthenium (II) complexes containing as ligands 2-(aminomethyl)pyridines and phosphines, proven to be extremely active catalysts in the reduction of ketones to alcohols via hydrogen transfer. By using 2-propanol as the hydrogen source with the ruthenium complexes, high yields of the corresponding alcohol can be rapidly obtained starting from linear and cyclic alkyl aryl, dialkyl and diaryl ketones. The conversion of ketones to alcohols can reach 100% if operating in a gaseous hydrogen atmosphere (2-3 atm). Where the phosphines used are optically active, starting from prochiral ketone compounds various types of optically active alcohols can be produced, being important intermediates in the pharmaceutical industry, in the agrochemical industry and for fine chemicals generally.
    Type: Application
    Filed: May 2, 2005
    Publication date: October 9, 2008
    Inventors: Walter Baratta, Katia Siega, Micaela Toniutti, Pierluigi Rigo