Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.

Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.

Abstract: Systems, devices, and methods for dispensing a of fluidic sample to each of a plurality of targets are disclosed. An example apparatus for dispensing a fluidic sample includes an inlet port to input a sample material, and a first sample nozzle and a second sample nozzle fluidically coupled to the inlet port to expel the sample material, wherein a tubular junction fluidically couples the inlet port to a first tubular fluid path that terminates in the first sample nozzle and to a second tubular fluid path that terminates in the second sample nozzle, wherein a cross-sectional area of the tubular junction is less than an average cross-sectional area of the first tubular fluid path and the second tubular fluid path, and wherein the cross-sectional area of the tubular junction is selected to draw the sample material from the inlet port into the tubular junction via capillary action.

Abstract: An apparatus for monitoring operation of at least one instrument using a transceiver device that communicates over a wired and/or wireless communication network. The apparatus includes a transceiver device configured to receive instrument data over the communication network. The instrument data are indicative of operation parameters of the at last one instrument. A hardware processor operationally coupled to the transceiver device is configured to process the instrument data in accordance with a customized interface. The hardware processor automatically provides a notification indicative of availability of instrument data results. A visual display is operationally coupled to the hardware processor and configured to display the instrument data results. A method of monitoring operation of at least one instrument via the wired and/or wireless communication network is also disclosed.

Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.

Abstract: A system and method are disclosed for effectuating a payment to a patient relating to the cost of pharmaceutical product between a discount payer, having a computing system including a processor, a memory, and an internet connection, and a patient. The method includes the steps of providing a discount manager, the discount manager having a computing system including a processor, a memory, and an internet connection, the discount manager facilitating the relationship between the discount payer and the patient; the system includes allowing all parties to align on, discuss, and debate who should receive a discount; the discount payer providing a payment, based on stakeholder alignment, to the patient for acquisition of the pharmaceutical product; and the patient receiving the payment, the payment received in the form of cash to the patient or as a credit to the discount manager for future use by the patient.

Abstract: Medical devices include stimulation and/or sensing circuitry that is interconnected to electrical components by a flexible circuit body having exposed portions of circuit traces that are attached to electrical contacts of the electrical components. Each circuit trace may span a separate window formed in an insulative body of the flexible circuit body, or a plurality of circuit traces may span a single window or may be freely extending from the insulative body. The exposed portion of the circuit trace may be plated with a conductive metal and then attached to the electrical contact of the electrical component. The flexible circuit body may be an extension from a flexible electrical circuit board containing the circuit. The circuit may be present on a circuit board that includes electrical contacts and where the flexible circuit body has exposed portions of circuit traces attached to the electrical contacts of the circuit board.

Abstract: A system for customizing management of one or more instruments in a laboratory includes a user device, an interface module and an instrument module. The user device is adapted to receive inputs from a user and has a device processor for processing the received inputs and instrument data from the one or more instruments, as well as a device display for displaying instrument information. The interface module is communicatively coupled with the user device and the one or more instruments and configured to convert instrument data in a first format generated by an instrument processor to a second format for processing by the device processor. The instrument module is configured to cause the device processor to provide customised instrument information on the device display. A method of deploying a platform for integrated management of instruments is also disclosed.

Abstract: Medical devices include stimulation and/or sensing circuitry that is interconnected to electrical components by a flexible circuit body having exposed portions of circuit traces that are attached to electrical contacts of the electrical components. Each circuit trace may span a separate window formed in an insulative body of the flexible circuit body, or a plurality of circuit traces may span a single window or may be freely extending from the insulative body. The exposed portion of the circuit trace may be plated with a conductive metal and then attached to the electrical contact of the electrical component. The flexible circuit body may be an extension from a flexible electrical circuit board containing the circuit. The circuit may be present on a circuit board that includes electrical contacts and where the flexible circuit body has exposed portions of circuit traces attached to the electrical contacts of the circuit board.

Abstract: Medical devices include stimulation and/or sensing circuitry that is interconnected to electrical components by a flexible circuit body having exposed portions of circuit traces that are attached to electrical contacts of the electrical components. Each circuit trace may span a separate window formed in an insulative body of the flexible circuit body, or a plurality of circuit traces may span a single window or may be freely extending from the insulative body. The exposed portion of the circuit trace may be plated with a conductive metal and then attached to the electrical contact of the electrical component. The flexible circuit body may be an extension from a flexible electrical circuit board containing the circuit. The circuit may be present on a circuit board that includes electrical contacts and where the flexible circuit body has exposed portions of circuit traces attached to the electrical contacts of the circuit board.

Abstract: A filtering capacitor feedthrough assembly for an implantable active medical device is disclosed. The filtering capacitor feedthrough assembly includes a capacitor having an aperture defined by an inner capacitor surface. The capacitor is electrically grounded to an electrically conductive feedthrough ferrule or housing of the implantable active medical device. A terminal pin extends into the aperture. An electrically conductive split ring sleeve is disposed within the aperture and between the terminal pin and the capacitor. The split ring sleeve includes a first end, a second end, a sleeve length therebetween. A longitudinal slit through the sleeve extends from the first end to the second end. The electrically conductive split ring sleeve mechanically securing and electrically coupling the terminal pin to the capacitor.

Abstract: Medical devices include stimulation and/or sensing circuitry that is interconnected to electrical components by a flexible circuit body having exposed portions of circuit traces that are attached to electrical contacts of the electrical components. Each circuit trace may span a separate window formed in an insulative body of the flexible circuit body, or a plurality of circuit traces may span a single window or may be freely extending from the insulative body. The exposed portion of the circuit trace may be plated with a conductive metal and then attached to the electrical contact of the electrical component. The flexible circuit body may be an extension from a flexible electrical circuit board containing the circuit. The circuit may be present on a circuit board that includes electrical contacts and where the flexible circuit body has exposed portions of circuit traces attached to the electrical contacts of the circuit board.

Abstract: A filtering capacitor feedthrough assembly for an implantable active medical device is disclosed. The filtering capacitor feedthrough assembly includes a capacitor having an aperture defined by an inner capacitor surface. The capacitor is electrically grounded to an electrically conductive feedthrough ferrule or housing of the implantable active medical device. A terminal pin extends into the aperture. An electrically conductive split ring sleeve is disposed within the aperture and between the terminal pin and the capacitor. The split ring sleeve includes a first end, a second end, a sleeve length therebetween. A longitudinal slit through the sleeve extends from the first end to the second end. The electrically conductive split ring sleeve mechanically securing and electrically coupling the terminal pin to the capacitor.

Abstract: A method of forming a filtering capacitor feedthrough assembly for an implantable active medical device includes inserting a terminal pin into an aperture of a capacitor, the capacitor configured to be electrically grounded to an electrically conductive feedthrough ferrule or housing of the implantable active medical device, then disposing an electrically conductive continuous coil within the aperture between the terminal pin and the capacitor and then fixing the continuous coil to the terminal pin or the capacitor. The continuous coil includes an inner diameter defined by a plurality of coils, the terminal pin extending through the inner diameter of the continuous coil so that the plurality of coils circumferentially surround the terminal pin. The electrically conductive continuous coil mechanically secures and electrically couples the terminal pin to the capacitor.

Abstract: A filtering capacitor feedthrough assembly for an implantable active medical device is disclosed. The filtering capacitor feedthrough assembly includes a capacitor having an aperture defined by an inner capacitor surface. The capacitor is electrically grounded to an electrically conductive feedthrough ferrule or housing of the implantable active medical device. A terminal pin extends into the aperture. An electrically conductive split ring sleeve is disposed within the aperture and between the terminal pin and the capacitor. The split ring sleeve includes a first end, a second end, a sleeve length therebetween. A longitudinal slit through the sleeve extends from the first end to the second end. The electrically conductive split ring sleeve mechanically securing and electrically coupling the terminal pin to the capacitor.

Abstract: Systems and techniques for determining in vivo mechanical load exerted on an implanted medical device (IMD) are described. A transfer function for determining a normal force exerted by a muscle based on an in-line force and muscle parameters is also described.

Abstract: Systems and techniques for determining in vivo mechanical load exerted on an implanted medical device (IMD) are described. The IMD or a device that has a substantially similar form factor as the IMD includes at least one mechanical stress sensor mechanically coupled to a housing or a component within the housing. In some examples, a patient parameter is determined based on a signal indicative of the in vivo mechanical load exerted on the IMD. In addition, in some examples, a processor determines whether a transient or cumulative mechanical load exerted on an IMD exceeded a predetermined threshold. A processor may additionally or alternatively determine whether a pattern in the mechanical loading of the IMD indicates a diversion from a manufacturing, shipping, storage or other handling process.

Abstract: A method of forming a filtering capacitor feedthrough assembly for an implantable active medical device includes inserting a terminal pin into an aperture of a capacitor, the capacitor configured to be electrically grounded to an electrically conductive feedthrough ferrule or housing of the implantable active medical device, then disposing an electrically conductive continuous coil within the aperture between the terminal pin and the capacitor and then fixing the continuous coil to the terminal pin or the capacitor. The continuous coil includes an inner diameter defined by a plurality of coils, the terminal pin extending through the inner diameter of the continuous coil so that the plurality of coils circumferentially surround the terminal pin. The electrically conductive continuous coil mechanically secures and electrically couples the terminal pin to the capacitor.

Abstract: A filtering capacitor feedthrough assembly for an implantable active medical device is disclosed. The filtering capacitor feedthrough assembly includes a capacitor having an aperture, the capacitor is electrically grounded to an electrically conductive feedthrough ferrule or housing of the implantable active medical device. A terminal pin extends into the aperture and an electrically conductive continuous coil is disposed within the aperture and between the terminal pin and the capacitor. The electrically conductive continuous coil mechanically secures and electrically couples the terminal pin to the capacitor.