Abstract: A modular tire pressure leak detection system includes a tire that supports a vehicle and a sensor unit mounted on the tire. The sensor unit detects real-time tire parameters inside the tire and transmits the parameters to a processor. A plurality of modules are in electronic communication with the processor. The plurality of modules include a pre-processing module that receives the parameters and applies a set of operations to generate pressure time series data, a leak detection module that receives the pressure time series data and determines a leak rate of the tire, and a post-processing module that receives the leak rate of the tire and analyzes the leak rate of the tire with determinations from a plurality of conditions. A leak alert is issued by the post-processing module based upon the analysis of the leak rate of the tire and the determinations from the plurality of conditions.