Patents by Inventor MICHA SAM BRICKMAN RAREDON

MICHA SAM BRICKMAN RAREDON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human and large-mammal lung bioreactor
    Patent number: 9986734
    Abstract: The present invention provides a bioreactor for large-mammal lung tissue. The bioreactor is capable of hydraulic driven negative-pressure and positive-pressure perfusion and ventilation. Perfusion and ventilation is delivered at physiological rates and is easily controllable. In one embodiment, the bioreactor comprises a support scaffold to support the size of a large-mammal lung tissue. In another embodiment, the bioreactor comprises a pleural sack that provides a small isolated fluid chamber which surrounds an engineered lung, thereby minimizing the amount of culture media needed. The present invention also provides an in vitro model for examining the function of a test agent and compositions and methods for alleviating a lung defect in a large-mammal.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: June 5, 2018
    Assignees: Yale University, Raredon Resources, Inc.
    Inventors: Micha Sam Brickman Raredon, Tom Raredon, Laura Niklason
  • HUMAN AND LARGE-MAMMAL LUNG BIOREACTOR
    Publication number: 20150289501
    Abstract: The present invention provides a bioreactor for large-mammal lung tissue. The bioreactor is capable of hydraulic driven negative-pressure and positive-pressure perfusion and ventilation. Perfusion and ventilation is delivered at physiological rates and is easily controllable. In one embodiment, the bioreactor comprises a support scaffold to support the size of a large-mammal lung tissue. In another embodiment, the bioreactor comprises a pleural sack that provides a small isolated fluid chamber which surrounds an engineered lung, thereby minimizing the amount of culture media needed. The present invention also provides an in vitro model for examining the function of a test agent and compositions and methods for alleviating a lung defect in a large-mammal.
    Type: Application
    Filed: June 25, 2015
    Publication date: October 15, 2015
    Inventors: MICHA SAM BRICKMAN RAREDON, TOM RAREDON, LAURA NIKLASON