Patents by Inventor Michael A. Brennan

Michael A. Brennan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11934796
    Abstract: The systems and methods described herein can generate a voice-based interface to increase the accuracy of translations. The voice-based interface can result in fewer input audio signals being transmitted between devices of a network. A method includes: receiving a first input audio signal; generating, based on the first input audio signal, a first translation string in a second language and a second translation string in a first language; determining a first translation score based on a likelihood that the first input audio signal includes an utterance in the first language and a second translation score based on a likelihood that the first input audio signal includes an utterance in the second language; selecting the first translation string based on the first translation score and the second translation score; generating an output signal from the first translation string; and transmitting the output signal to the client device.
    Type: Grant
    Filed: June 13, 2022
    Date of Patent: March 19, 2024
    Assignee: GOOGLE LLC
    Inventors: Michael Greenberg, Bertrand Damiba, Olivia Grace, Fei Wu, Shane Brennan
  • Patent number: 11913902
    Abstract: A food wash reference fluid delivery apparatus includes a portable reference fluid reservoir comprising an inlet and an outlet and configured to store a reference fluid that includes a predetermined concentration of an analyte, a pump fluidly coupled to the outlet of the portable reference fluid reservoir and configured to pump the reference fluid from the outlet of the portable reference fluid reservoir, a sensor connector configured to fluidly couple with a sensor positioned along a fluid flow path of the food wash system, a sensor fluid line configured to provide the reference fluid from the pump to the sensor connector, an inlet fluid line configured to provide the reference fluid from the pump to the inlet of the portable reference fluid reservoir, and a valve configured to adjustably control a fluid flow rate of the reference fluid through the sensor fluid line and the inlet fluid line.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: February 27, 2024
    Assignee: SMARTWASH SOLUTIONS, LLC
    Inventors: James M. Brennan, Eric Child Wilhelmsen, Danny Elmer Lindstrom, Christopher Michael McGinnis
  • Patent number: 11890275
    Abstract: The present embodiments relate to substituted heterocyclic derivative therapeutic compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of diseases mediated by aberrant cell signalling, such as inflammatory disorders, cancer and neoplastic disease. Particular compounds described herein exhibit selective inhibitory activity against CBP compared with BRD4.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: February 6, 2024
    Inventors: Lynnie Trzoss, Juan Manuel Betancort, Toufike Kanouni, Michael Brennan Wallace, Amogh Boloor
  • Patent number: 11884648
    Abstract: The present embodiments provide for substituted triazolylpyridine derivative compounds, and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for modulating the activity of histone demethylase enzymes. Additionally, the subject compounds and compositions are useful for the treatment of cancer or other neoplastic diseases, or maladies associated with abnormal histone demethylase activity. Accordingly, the substituted triazolylpyridine derivative compounds described herein are useful in methods and medicaments for treating cancer.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: January 30, 2024
    Assignee: Celgene Quanticel Research, Inc.
    Inventors: Zhe Nie, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
  • Publication number: 20230286917
    Abstract: The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted amidopyridine or amidopyridazine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
    Type: Application
    Filed: March 24, 2023
    Publication date: September 14, 2023
    Applicant: CELGENE QUANTICEL RESEARCH, INC.
    Inventors: Young K. Chen, Toufike Kanouni, Zhe Nie, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
  • Publication number: 20230264970
    Abstract: Compositions comprise a perovskite and a non-perovskite. Perovskites comprise AxA?yA?(1?x?y)BX3, and non-perovskites may comprise A?, B and X, where A is a first cation, A? is a second cation, A? is a third cation, B is a fourth cation, X is an anion. In some instances, A, A?, and A? are each independently (NH2)2CH+, CH3NH3+, Cs+, Rb+, or (NH2)2(C?NH2)+, with the proviso that A, A?, and A? are each different. The perovskite may have a first crystal structure in which the anion is corner-sharing, the non-perovskite may have a second crystal structure comprising at least one of an orthorhombic structure, a hexagonal structure, or a perovskite-like structure, and 1?x?y may be greater than about 0.15.
    Type: Application
    Filed: July 2, 2021
    Publication date: August 24, 2023
    Inventors: Masaru KUNO, Michael BRENNAN, Anthony RUTH, Ilia PAVLOVETC, Jeffrey A. CHRISTIANS, Taylor Hennessey MOOT, Joseph Matthew LUTHER
  • Patent number: 11731954
    Abstract: The present disclosure relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyridine derivative compounds, and compositions (including pharmaceutical compositions) that include these compounds. The subject compounds and compositions are useful for inhibition of at least one histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer or neoplastic disease, such as prostate cancer, breast cancer, bladder cancer, lung cancer, melanoma, retinoblastoma, or multiple endocrine neoplasia type 1.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: August 22, 2023
    Inventors: Young K. Chen, Michael Brennan Wallace
  • Patent number: 11639333
    Abstract: The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted amidopyridine or amidopyridazine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: May 2, 2023
    Assignee: CELGENE QUANTICEL RESEARCH, INC
    Inventors: Young K. Chen, Toufike Kanouni, Zhe Nie, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
  • Publication number: 20230117519
    Abstract: The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyrido[3,4-d]pyrimidin-4-one derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
    Type: Application
    Filed: November 3, 2022
    Publication date: April 20, 2023
    Applicant: CELGENE QUANTICEL RESEARCH, INC.
    Inventors: Amogh Boloor, Toufike Kanouni, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
  • Patent number: 11535616
    Abstract: The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyrido[3,4-d]pyrimidin-4-one derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
    Type: Grant
    Filed: September 21, 2020
    Date of Patent: December 27, 2022
    Assignee: CELGENE QUANTICEL RESEARCH, INC
    Inventors: Amogh Boloor, Toufike Kanouni, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
  • Publication number: 20220298073
    Abstract: Described herein are cementitious compositions comprising biochar and methods of making such compositions. The compositions find use in a variety of applications, including use in a variety of building materials and building applications.
    Type: Application
    Filed: March 18, 2022
    Publication date: September 22, 2022
    Inventors: Michael Brennan Pecha, Lori Elizabeth Tunstall, Julia Hylton
  • Publication number: 20220029293
    Abstract: Various embodiments that pertain to a loop antenna are described. The loop antenna can be a single loop antenna that switches between a first phase and a second phase. While operating at different phases, the loop antenna can function at the same frequency. The loop antenna can observe a response to the frequency at the first phase and the frequency at the second phase. This can provide a wider range of information over operation in a single phase.
    Type: Application
    Filed: October 7, 2021
    Publication date: January 27, 2022
    Inventors: Bing Mak, Adam Melber, Daniel Heinz, Michael Brennan
  • Patent number: 11214542
    Abstract: The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted amidopyridine or amidopyridazine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: January 4, 2022
    Assignee: CELGENE QUANTICEL RESEARCH, INC.
    Inventors: Young K. Chen, Toufike Kanouni, Zhe Nie, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
  • Patent number: 11145981
    Abstract: Various embodiments that pertain to a loop antenna are described. The loop antenna can be a single loop antenna that switches between a first phase and a second phase. While operating at different phases, the loop antenna can function at the same frequency. The loop antenna can observe a response to the frequency at the first phase and the frequency at the second phase. This can provide a wider range of information over operation in a single phase.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 12, 2021
    Assignee: The Government of the United States, as represented by the Secretary of the Army
    Inventors: Bing Mak, Adam Melber, Daniel Heinz, Michael Brennan
  • Publication number: 20210238161
    Abstract: The present disclosure relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyridine derivative compounds, and compositions (including pharmaceutical compositions) that include these compounds. The subject compounds and compositions are useful for inhibition of at least one histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer or neoplastic disease, such as prostate cancer, breast cancer, bladder cancer, lung cancer, melanoma, retinoblastoma, or multiple endocrine neoplasia type 1.
    Type: Application
    Filed: April 12, 2021
    Publication date: August 5, 2021
    Applicant: CELGENE QUANTICEL RESEARCH, INC.
    Inventors: Young K. Chen, Michael Brennan Wallace
  • Publication number: 20210205284
    Abstract: The present embodiments relate to substituted heterocyclic derivative therapeutic compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of diseases mediated by aberrant cell signalling, such as inflammatory disorders, cancer and neoplastic disease. Particular compounds described herein exhibit selective inhibitory activity against CBP compared with BRD4.
    Type: Application
    Filed: March 15, 2021
    Publication date: July 8, 2021
    Applicant: CELGENE QUANTICEL RESEARCH, INC.
    Inventors: Lynnie TRZOSS, Juan Manuel BETANCORT, Toufike KANOUNI, Michael Brennan WALLACE, Amogh BOLOOR
  • Patent number: 11020380
    Abstract: The present embodiments relate to substituted heterocyclic derivative therapeutic compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of diseases mediated by aberrant cell signalling, such as inflammatory disorders, cancer and neoplastic disease. Particular compounds described herein exhibit selective inhibitory activity against CBP compared with BRD4.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: June 1, 2021
    Assignee: CELGENE QUANTICEL RESEARCH, INC.
    Inventors: Lynnie Trzoss, Juan Manuel Betancort, Toufike Kanouni, Michael Brennan Wallace, Amogh Boloor
  • Publication number: 20210139460
    Abstract: The present embodiments provide for substituted triazolylpyridine derivative compounds, and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for modulating the activity of histone demethylase enzymes. Additionally, the subject compounds and compositions are useful for the treatment of cancer or other neoplastic diseases, or maladies associated with abnormal histone demethylase activity. Accordingly, the substituted triazolylpyridine derivative compounds described herein are useful in methods and medicaments for treating cancer.
    Type: Application
    Filed: November 13, 2020
    Publication date: May 13, 2021
    Applicant: CELGENE QUANTICEL RESEARCH, INC.
    Inventors: Zhe NIE, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
  • Patent number: 11001568
    Abstract: The present disclosure relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyridine derivative compounds, and compositions (including pharmaceutical compositions) that include these compounds. The subject compounds and compositions are useful for inhibition of at least one histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer or neoplastic disease, such as prostate cancer, breast cancer, bladder cancer, lung cancer, melanoma, retinoblastoma, or multiple endocrine neoplasia type 1.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: May 11, 2021
    Assignee: CELGENE QUANTICEL RESEARCH, INC.
    Inventors: Young K. Chen, Michael Brennan Wallace
  • Publication number: 20210133597
    Abstract: In an approach to mapping marketing triggers across geographies, a computer receives one or more variables associated with one or more rulesets. A computer retrieves data corresponding to the one or more variables. A computer sorts the retrieved data by season. A computer computes a seasonal average for each variable by associated postal code. A computer trains a self-organizing map to arrange the data associated with the source geography postal codes into one or more source clusters. A computer maps the retrieved data and the computed data associated with the target geography to the one or more source clusters, thereby creating target counterpart clusters that correspond with at least one of the one or more source clusters. A computer applies one or more cluster rulesets associated with the one or more source clusters to the corresponding one or more target counterpart clusters. A computer outputs one or more bucket sheets.
    Type: Application
    Filed: November 4, 2019
    Publication date: May 6, 2021
    Inventors: David Arthur Gold, Leonard G. Polhemus, JR., Robert Donald Hamilton, Declan Michael Brennan