Patents by Inventor Michael A. Cummins
Michael A. Cummins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220364275Abstract: The present invention relates to a polyolefin fiber comprising polymeric structures, wherein the polymeric structures individually comprise a polycondensate and a functionalized polymer, and the polyolefin fiber is a gel-spun high-performance polyethylene fiber that has a tenacity of at least 1 N/tex. The polymeric structures are immiscible with and dispersed in the polyethylene fiber. The gel-spun high-performance polyethylene fiber is a gel-spun ultrahigh molecular weight polyethylene fiber.Type: ApplicationFiled: November 3, 2020Publication date: November 17, 2022Inventors: Luigi BALZANO, Franciscus Wilhelmus, Maria GELISSEN, Francois Antoine, Marie OP DEN BUIJSCH, David Michael CUMMINS
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Publication number: 20220187324Abstract: Disclosed are methods and systems for determining concentrations of a target molecule and a variant thereof in a sample. The sample can comprise or be suspected to comprise a target molecule and at least one variant thereof and is exposed to one or more recognition elements that bind to the target molecule and/or the at least one variant. A signal is detected that is associated with the binding of the target molecule and/or a signal is detected that is associated with the binding of the at least one variant to the one or more recognition elements. The concentration of the target molecule and/or the at least one variant thereof is determined based on the signals. The system can comprise a receiver adapted to receive a sample comprising or suspected to comprise a target molecule and the at least one variant thereof, the receiver comprising one or more recognition elements that bind to one or more epitopes in the target molecule and/or the at least one variant thereof.Type: ApplicationFiled: March 1, 2022Publication date: June 16, 2022Inventors: Brian Michael Cummins, Frances Smith Ligler, Glenn Walker
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Patent number: 11293932Abstract: Disclosed are methods and systems for determining concentrations of a target molecule and a variant thereof in a sample. The sample can comprise or be suspected to comprise a target molecule and at least one variant thereof and is exposed to one or more recognition elements that bind to the target molecule and/or the at least one variant. A signal is detected that is associated with the binding of the target molecule and/or a signal is detected that is associated with the binding of the at least one variant to the one or more recognition elements. The concentration of the target molecule and/or the at least one variant thereof is determined based on the signals. The system can comprise a receiver adapted to receive a sample comprising or suspected to comprise a target molecule and the at least one variant thereof, the receiver comprising one or more recognition elements that bind to one or more epitopes in the target molecule and/or the at least one variant thereof.Type: GrantFiled: December 20, 2019Date of Patent: April 5, 2022Assignee: North Carolina State UniversityInventors: Brian Michael Cummins, Frances Smith Ligler, Glenn Walker
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Patent number: 11280589Abstract: Composite panel comprising at least one layer containing at least one tape comprising a thermoplastic polymer selected from the group consisting of polyolefins, polyesters, polyvinyl alcohols, polyacrylonitriles, polyamides or polyketone, wherein the tape has a tensile strength of at least 1.2 GPa and an areal density of between 5 and 150 g/m2, and an adhesive in contact with said layer, whereby the amount of the adhesive in contact with one side of the at least one layer is between 0.2 and 15 g/m2, wherein the adhesive is a plastomer wherein said plastomer is a random copolymer of ethylene or propylene and one or more C2 to C12 a-olefin co-monomers and wherein said plastomer has a density as measured according to 1801183 of between 860 and 930 kg/m3. In a preferred embodiment the tape comprises an ultra high molecular weight polyethylene. The composite panel is used in a ballistic resistant article.Type: GrantFiled: March 7, 2013Date of Patent: March 22, 2022Assignee: DSM IP ASSETS B.V.Inventors: David Michael Cummins, Dietrich Wienke, Roelof Marissen, Koen Van Putten, Joke Hendrix
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Publication number: 20210068886Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.Type: ApplicationFiled: November 16, 2020Publication date: March 11, 2021Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Mark Gelfand, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Mark S. Leung, Gwenda Francis, Barry Mullins, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Michael Turovskiy
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Patent number: 10842547Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.Type: GrantFiled: December 14, 2018Date of Patent: November 24, 2020Assignee: MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Mark Gelfand, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Mark S. Leung, Gwenda Francis, Barry Mullins, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Michael Turovskiy
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Publication number: 20200200772Abstract: Disclosed are methods and systems for determining concentrations of a target molecule and a variant thereof in a sample. The sample can comprise or be suspected to comprise a target molecule and at least one variant thereof and is exposed to one or more recognition elements that bind to the target molecule and/or the at least one variant. A signal is detected that is associated with the binding of the target molecule and/or a signal is detected that is associated with the binding of the at least one variant to the one or more recognition elements. The concentration of the target molecule and/or the at least one variant thereof is determined based on the signals. The system can comprise a receiver adapted to receive a sample comprising or suspected to comprise a target molecule and the at least one variant thereof, the receiver comprising one or more recognition elements that bind to one or more epitopes in the target molecule and/or the at least one variant thereof.Type: ApplicationFiled: December 20, 2019Publication date: June 25, 2020Inventors: Brian Michael Cummins, Frances Smith Ligler, Glenn Walker
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Patent number: 10545158Abstract: Disclosed are methods and systems for determining concentrations of a target molecule and a variant thereof in a sample. The sample can comprise or be suspected to comprise a target molecule and at least one variant thereof and is exposed to one or more recognition elements that bind to the target molecule and/or the at least one variant. A signal is detected that is associated with the binding of the target molecule and/or a signal is detected that is associated with the binding of the at least one variant to the one or more recognition elements. The concentration of the target molecule and/or the at least one variant thereof is determined based on the signals. The system can comprise a receiver adapted to receive a sample comprising or suspected to comprise a target molecule and the at least one variant thereof, the receiver comprising one or more recognition elements that bind to one or more epitopes in the target molecule and/or the at least one variant thereof.Type: GrantFiled: December 28, 2015Date of Patent: January 28, 2020Assignee: North Carolina State UniversityInventors: Brian Michael Cummins, Frances Smith Ligler, Glenn Walker
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Publication number: 20190183556Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.Type: ApplicationFiled: December 14, 2018Publication date: June 20, 2019Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Mark Gelfand, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Mark S. Leung, Gwenda McMullin, Barry Mullins, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vicenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Michael Turovskiy
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Patent number: 10188445Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.Type: GrantFiled: August 5, 2016Date of Patent: January 29, 2019Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Mark Gelfand, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Mark S. Leung, Gwenda Francis, Barry Mullins, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Michael Turovskiy
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Publication number: 20170056087Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.Type: ApplicationFiled: August 5, 2016Publication date: March 2, 2017Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Mark Gelfand, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Mark S. Leung, Gwenda McMullin, Barry Mullins, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vicenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Michael Turovskiy
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Patent number: 9439708Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.Type: GrantFiled: October 23, 2011Date of Patent: September 13, 2016Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Gwenda McMullin, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Mark Gelfand, Mark S. Leung, Barry Mullins, Michael Turovskiy
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Patent number: 9101473Abstract: Endovascular prostheses are disclosed that are configured to repair a native venous valve having improper or non-existent valve leaflet coaptation caused by vessel weakness and/or distention. The prostheses are configured to be implanted in the venous system immediately downstream of the malfunctioning valve and act as repair devices to restore proper function to the venous valve by reconfiguring and supporting the valve leaflets and thereby improving their coaptation.Type: GrantFiled: March 7, 2013Date of Patent: August 11, 2015Assignee: Medtronic Vascular, Inc.Inventors: Fiachra Sweeney, Michael Cummins, Kent Martin, Stefanie Ahlrichs
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Patent number: 9060754Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment includes an elongated shaft and a cooling assembly at a distal portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site within or otherwise proximate a renal artery. The cryotherapeutic device can further include a supply lumen configured to carry liquid refrigerant toward the cooling assembly. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when in a deployed state.Type: GrantFiled: October 23, 2011Date of Patent: June 23, 2015Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Seamus Ledwith, Gwenda McMullin, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Mark Gelfand, Mark S. Leung, Barry Mullins
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Patent number: 9060755Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.Type: GrantFiled: October 23, 2011Date of Patent: June 23, 2015Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Naomi Buckley, Michael Cummins, Danny Donovan, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Micheal Moriarty, Karun D. Naga, Fiachra Sweeney, Vincenzo Tilotta, Ronan Wood, Lana Woolley, Denise Zarins, Mark S. Leung, Mark Gelfand, Barry Mullins
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Publication number: 20150033936Abstract: Composite panel comprising at least one layer containing at least one tape comprising a thermoplastic polymer selected from the group consisting of polyolefins, polyesters, polyvinyl alcohols, polyacrylonitriles, polyamides or polyketone, wherein the tape has a tensile strength of at least 1.2 GPa and an areal density of between 5 and 150 g/m2, and an adhesive in contact with said layer, whereby the amount of the adhesive in contact with one side of the at least one layer is between 0.2 and 15 g/m2, wherein the adhesive is a plastomer wherein said plastomer is a random copolymer of ethylene or propylene and one or more C2 to C12 a-ol-efin co-monomers and wherein said plastomer has a density as measured according to 1801183 of between 860 and 930 kg/m3. In a preferred embodiment the tape comprises an ultra high molecular weight polyethylene. The composite panel is used in a ballistic resistant article.Type: ApplicationFiled: March 7, 2013Publication date: February 5, 2015Inventors: David Michael Cummins, Dietrich Wienke, Roelof Marissen, Koen Van Putten, Joke Hendrix
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Patent number: 8945107Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.Type: GrantFiled: October 23, 2011Date of Patent: February 3, 2015Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Seamus Ledwith, Gwenda McMullin, Karun D. Naga, Stephen Nash, Francesco Piccagli, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Mark Gelfand, Mark S. Leung, Barry Mullins
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Publication number: 20140257463Abstract: Endovascular prostheses are disclosed that are configured to repair a native venous valve having improper or non-existent valve leaflet coaptation caused by vessel weakness and/or distention. The prostheses are configured to be implanted in the venous system immediately downstream of the malfunctioning valve and act as repair devices to restore proper function to the venous valve by reconfiguring and supporting the valve leaflets and thereby improving their coaptation.Type: ApplicationFiled: March 7, 2013Publication date: September 11, 2014Applicant: MEDTRONIC VASCULAR, INC.Inventors: Fiachra Sweeney, Michael Cummins, Kent Martin, Stefanie Ahlrichs
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Publication number: 20130291712Abstract: The invention relates to a multi-ballistic-impact resistant article comprising a plurality of stacked monolayers (103), at least part of the monolayers (103) containing at least one polyolefin tape, characterized in that said plurality of stacked monolayers (103) has a total areal density of less than 200 Kg/m2 and wherein said article is able to withstand at least three ballistic impacts from 20 mm FSP without complete penetration.Type: ApplicationFiled: September 7, 2011Publication date: November 7, 2013Applicant: DSM IP ASSETS B.V.Inventors: Martin Antonius Van Es, Ronny Jacob Jensz, David Michael Cummins
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Patent number: D929747Type: GrantFiled: November 22, 2017Date of Patent: September 7, 2021Assignee: DSM IP ASSETS B.V.Inventors: David Michael Cummins, Dietrich Wienke, Roelof Marissen, Koen Van Putten, Joke Hendrix