Abstract: The present invention relates to a recombinant signal sequence derived from E. coli. The invention also relates to a fusion protein comprising the signal sequence, a recombinant protein and methods of producing the recombinant protein. The recombinant signal sequence can be used to provide a method for controlling the viscosity of the fermentation, and/or controlling basal (pre-induction) expression of the recombinant protein.

Abstract: Systems and methods are provided for adjusting point of sale (POS) interfaces. In some embodiments, a POS device includes a display. The display is configured to present a user interface, the user interface having a first interface and a second interface. The first interface has a first set of functionalities that is prevented from being accessible in the second interface.

Abstract: A method of forming a polycrystalline diamond body includes mixing a sintering agent with diamond powder to form a premixed layer, the sintering agent including at least one alkaline eat mewl carbonate; forming an infiltration layer adjacent to the premixed layer, the infiltration layer including an infiltrant material including at least one alkaline earth metal carbonate; and subjecting the premixed layer and the infiltration layer to high pressure high temperature conditions.

Abstract: An interaction assistant conducts multiple turn interaction dialogs with a user in which context is maintained between turns, and the system manages the dialog to achieve an inferred goal for the user. The system includes a linguistic interface to a user and a parser for processing linguistic events from the user. A dialog manager of the system is configured to receive alternative outputs from the parser, and selecting an action and causing the action to be performed based on the received alternative outputs. The system further includes a dialog state for an interaction with the user, and the alternative outputs represent alternative transitions from a current dialog state to a next dialog state. The system further includes a storage for a plurality of templates, and wherein each dialog state is defined in terms of an interrelationship of one or more instances of the templates.

Abstract: Suture clip deployment devices for applying suture clips to sutures are described. Some embodiments can include a generally tubular main body and a vacuum port located at the distal end, a hollow inner body longitudinally slidable within the main body and extending from the main body at its distal end, and a suture recess located in the generally tubular main body. At least one suture clip configured to frictionally fit on an outer surface of the inner body is deployed during use. Clip deployment can occur after a vacuum source is applied to the device so as to draw the suture into the device. The suture lines can be retrieved through the suture recess, and the device can be actuated so as to deliver the suture clip off the delivery device and onto the suture, locking the suture in place.

Abstract: A heat exchanger from a stack of plate pairs having fins which are disposed between the plate pairs, and having ducts which vertically extend through the stack, for conveying in and/or conveying out a medium which flows through the plate pairs and which exchanges heat with another medium which flows through the fins, wherein the ducts are formed from openings in the plates and have moldings which extend around opening peripheries, and having a plate, having corresponding openings, which finishes off the stack, wherein a thermally decoupling element, which is inserted either in an integrated or a separate manner and which is incorporated into the vertical duct formation, is disposed between the finishing-off plate and the stack. Such a heat exchanger displays improved resilience to alternating temperature loadings.

Abstract: Deposition of carbene monolayers that excluded starting anions, such as iodide ions, has been achieved. Anions such as iodide are a typical contaminant in carbene hydrogen carbonate salts when synthesized using the state-of-the-art method. A method is described for eliminating substantially all starting anion (e.g., iodide) contamination from the monolayer. Air stable, purified carbenes precursors were used to deposit an intact monolayer on the surface of some industrially relevant metals. The monolayer's ability to protect these metals against, for example, oxidation has been demonstrated.

Abstract: A cannula assembly is provided, the cannula assembly comprising a cannula, in particular a graft, for forming a flow channel for bodily fluids, in particular for blood, and a protective element for the cannula, wherein the protective element defines a channel for the cannula, wherein the cannula runs through the channel of the protective element at least in sections, wherein the protective element comprises a plurality of segments, wherein the segments are arranged next to one another in a sequence and wherein each segment defines a sub-section of the channel of the protective element. A blood pump assembly and a method for using the cannula assembly and the blood pump assembly are also provided.

Abstract: In one embodiment, the present invention includes a method of alignment for resection of tissue including obtaining a surgical device comprising an alignment guide, a first guide structure and a second guide structure; securing the alignment guide to a bone, the alignment guide including a positioning block; placing the first guide structure onto the positioning block of the alignment guide; viewing a target location of a first resection plane on the bone using the first guide structure; adjusting the target location of the first resection plane by adjusting a position of the first guide structure; attaching the second guide structure to the first guide structure; viewing a target location of a second resection plane on the bone using the second guide structure; and adjusting the target location of the second resection plane by adjusting a position of the second guide structure.

Abstract: Customer churn risk scores are based on a multi-variable churn risk model relating customer and customer account characteristics to a risk of customer churn. A computer-implemented method of generating and presenting churn risk scores of customers of a telecommunication provider involves analyzing, on an in-memory database platform, customer call data records and customer records to calculate a churn likelihood value, an influence factor value, and an average spend value for each customer. The method assigns a churn risk score to each customer according to the model using the calculated churn likelihood value, the calculated influence factor value, and the calculated average spend value as input to the model. The churn risk scores for one or more customers are displayed visually on an interactive computer-user interface (UI).

Abstract: An aqueous cleaning composition, which may be suitable for use in cleaning hard surfaces, is described. The aqueous cleaning composition includes an ionic liquid solvent, an amino alcohol, and a substantial amount of water. The cleaning compositions may also include a disinfecting quaternary surfactant, a nonionic surfactant, such as an ethoxylated alcohol and/or alkyl polyglycoside, and/or a chelating agent, such as an aminopolycarboxylate chelating agent.

Abstract: Provided herein are pharmaceutically acceptable compositions containing a selective cyclooxygenase-2 (COX-2) inhibitor (coxib) and optionally buprenorphine. In particular, compositions containing a coxib formulated for oral, topical or subcutaneous administration to treat pain or inflammation are described.

Abstract: UV-cured pressure sensitive adhesive including one or more UV-curable acrylic oligomers, one or more tack control components, and, optionally, an elastomeric material is described herein. The adhesive includes an adhesive component ratio of the various adhesive components effective to provide desired first peel adhesions and subsequent peel adhesions.

Abstract: A computer-implemented technique is described herein for presenting notifications on a user interface presentation of a recipient computing device. The technique is considered tiered because it distinguishes between first-type (people-centric) notifications and second-type notifications, and because it processes and presents first-type notifications in a privileged manner compared to the second-type notifications. For instance, the technique presents content associated with each first-type notification in an allocated window that appears in positional association with a person indicator, where that person indicator identifies the person who sent the first-type notification; the technique presents each second-type notification in a different manner. In some implementations, an application developer who designs a custom first-type notification is given authority to draw within the allocated window that is used to present the custom first-type notification in a manner specified by the application developer.

Abstract: The present invention provides a composition comprising a high load of metal oxides that is phase stable and sprayable. It comprises a branched hydrophobically modified ethoxylated urethane copolymer and a hydrophobically modified alkali swellable emulsion copolymer comprising of one or more acrylate monomers and an ethoxylated associative comonomer.

Abstract: A method, system or apparatus including a server that may receive information from a computer, store the information in a database at the server, determine a reader device to receive the information based on an analysis of a reader device identifier, and transmit viral data to a mobile device where the viral data includes at least a portion of the information.

Abstract: The present invention relates to a process for producing surface-postcrosslinked water-absorbent polymer particles by coating of water-absorbent polymer particles having a content of residual monomers in the range from 0.03 to 15% by weight with at least one surface-postcrosslinker and thermal surface-postcrosslinking at temperatures in the range from 100 to 180° C.

Abstract: The present invention provides improved methods for gene delivery to, or genetic modification of target cells, wherein the gene delivery or other genetic modification of the target cells is performed in the presence of endothelial cells, or after co-culture of the target cells with endothelial cells, or wherein co-culture of the target cells with endothelial cells is employed immediately alter gene delivery in order to “rescue” cells that may have been damaged during the gene delivery process. In some embodiments gene delivery is performed by transfection. In some embodiments gene delivery is performed by transduction, in some embodiments the endothelial cells are organ-specific endothelial cells. In some embodiments the endothelial cells are E40RF1-expressing endothelial cells (E40RF1+ ECs). In some embodiments the target cells are stem cells, such as hematopoietic stem cells.

Abstract: The invention provides improved filtration materials and mediums accommodating to various filter types and designs. Materials/mediums include both “raw” cannabis (cannabinoids) as filter components such as but not limited to fibers, as well as altered materials (compounds) such as but not limited to sponges. These materials/mediums can be fashioned into any form, shape, density or design such as but not limited to inserts for faucet attachments, mechanical oil filters, or home AC filters. A primary feature of cannabis in use as filtration material is the anti-bacterial/-microbial properties. Trace cannabinoids found in all cannabis remain chemically active through material processing, providing a surficial efficacy as high as 99% with regard to sanitizing effects. Specifically as liquids, gases or solids come in contact with these materials/mediums they will be “sanitized” while the materials/mediums also capture particulates, compared to UV or chlorine treatment—neither of which removes particulates.

Abstract: An ultrasonic diagnostic imaging system and method enable the automatic acquisition of standard view planes of the heart in real time, such as the AP4, AP3, and AP2 views. A 3D image of the heart is acquired and the processed in conjunction with a geometrical heart model. The heart model is fitted to the heart in its acquired pose to segment the desired image planes from the 3D image data. During successive image acquisition intervals the image planes are tracked through successive image data as a multi-plane system to update a display of the multiple images. The successive image acquisitions can be volume image acquisitions or multi-plane acquisitions of just the tracked image planes during each acquisition interval.