Abstract: Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.

Abstract: Methods and apparatus for providing protected content to subscribers of a managed (e.g., MSO) network via a content source accessible via an internetwork such as the Internet. In one embodiment, a user accesses a service provider portal (e.g., website), and requests content. The service provider determines whether the requesting user is permitted to access the content, and what rights or restrictions are associated with the user. This includes authenticating the user as a subscriber of the MSO, and determining the subscriber's subscription level. In another embodiment, a user's account with the MSO and service provider may be federated, thus a given user will have MSO-specific information regarding its identity (such as login information, GUID, etc.) and is able to perform a single sign on to request and receive content.

Abstract: Embodiments described herein relate to apparatus for temperature modulation of samples. Generally, aspects of the disclosure provide for a portable cooling and heating apparatus which enables a user to visualize a sample during cooling or heating. In one embodiment, the apparatus include a sample block, a plurality of thermoelectric modules coupled to the sample block, and a cooling block coupled to the plurality of thermoelectric modules. In another embodiment, the cooling block is in fluid communication with a fluid reservoir. Other embodiments utilize various insulating materials to influence thermal conductivity between the sample block and the cooling block to provide for enhanced temperature control and modulation.

Abstract: A computing system receives a request to generate one or more narrative frameworks for a worksheet. The worksheet is hosted by a third party server. The computing system interfaces with the third party server to retrieve data associated with the worksheet. The computing system infers attributes of the worksheet from the retrieved data. The attributes correspond to a type of data represented in the worksheet. The computing system generates a narrative template for the one or more narrative frameworks. The computing system generates one or more data variables for the one or more narrative frameworks based on the generated narrative template. The computing system constructs the one or more narrative frameworks by selectively retrieving data from the worksheet for each data variable of the one or more data variables in the narrative framework.

Abstract: Over-the-air radio broadcast signals are commonly used to deliver a variety of programming content (e.g., audio, etc.) to radio receiver systems. Supplemental data (e.g., metadata) may be provided to radio broadcast receiver systems, where such supplemental data is associated with the programming content delivered via the over-the-air radio broadcast signals. In exemplary embodiments described herein, a radio receiver system receives both (i) primary programming content via over-the-air radio broadcast transmission, and (ii) metadata related to the programming content via wireless Internet. This use of metadata provides a user with an enhanced experience regardless of the type of terrestrial broadcast signal that is received at the user's radio receiver system. Users receiving radio broadcast signals at a receiver system may view images, videos, multimedia displays, text, etc., that is related to the programming content received via the over-the-air radio broadcast signals.

Abstract: Methods and apparatus for providing protected content to subscribers of a managed (e.g., MSO) network via a content source accessible via an internetwork such as the Internet. In one embodiment, a user accesses a service provider portal (e.g., website), and requests content. The service provider determines whether the requesting user is permitted to access the content, and what rights or restrictions are associated with the user. This includes authenticating the user as a subscriber of the MSO, and determining the subscriber's subscription level. In another embodiment, a user's account with the MSO and service provider may be federated, thus a given user will have MSO-specific information regarding its identity (such as login information, GUID, etc.) and is able to perform a single sign on to request and receive content.

Abstract: A system comprises an intermediate communication platform that provides an interface to an Internet network; and a first server including: a port operatively coupled to the intermediate communication platform, processing circuitry, and a service application for execution by the processor. The service application is configured to: receive audio content recognition information from a first radio receiver of multiple radio receivers via the intermediate communication platform, wherein the audio content recognition information identifies audio content received by the first receiver in a radio broadcast; determine audio metadata associated with the received audio content recognition information; and send the audio metadata to the multiple radio receivers via the intermediate communication platform.

Abstract: Methods and apparatus for providing protected content to subscribers of a managed (e.g., MSO) network via a content source accessible via an internetwork such as the Internet. In one embodiment, a user accesses a programmer website, and requests content. The programmer determines whether the requesting user is permitted to access the content, and what rights or restrictions are associated with the user. This includes authenticating the user as a subscriber of the MSO, and determining the subscriber's subscription level. In another embodiment, a user's account with the MSO and programmer may be federated, thus a given user will have MSO-specific information regarding its identity (such as login information, GUID, etc.) and/or information regarding subscription level and service details, stored at the programmer. Messages received from the MSO representing permission for the user to access content may also be stored at the programmer site for later reference.

Abstract: A system comprises a first server including a port, a memory, a processor operatively coupled to the port and memory, and a service application for execution by the processor. The service application is configured to: receive identification information related to an over-the-air radio broadcast via the port of the first server, wherein the identification information is transmitted to the first server using a radio broadcast receiver remote from the first server; communicate a request for automatic content recognition (ACR) of an Internet-based streaming version of the over-the-air radio broadcast; and receive metadata associated with the over-the-air radio broadcast in response to the request and initiate transmission of the metadata to the radio broadcast receiver.

Abstract: Methods and apparatus for providing protected content to subscribers of a managed (e.g., MSO) network via a content source accessible via an internetwork such as the Internet. In one embodiment, a user accesses a programmer website website, and requests content. The programmer determines whether the requesting user is permitted to access the content, and what rights or restrictions are associated with the user. This includes authenticating the user as a subscriber of the MSO, and determining the subscriber's subscription level. In another embodiment, a user's account with the MSO and programmer may be federated, thus a given user will have MSO-specific information regarding its identity (such as login information, GUID, etc.) and/or information regarding subscription level and service details, stored at the programmer. Messages received from the MSO representing permission for the user to access content may also be stored at the programmer site for later reference.

Abstract: A system comprises a first server including a port, a memory, a processor operatively coupled to the port and memory, and a service application for execution by the processor. The service application is configured to: receive identification information related to an over-the-air radio broadcast via the port of the first server, wherein the identification information is transmitted to the first server using a radio broadcast receiver remote from the first server, communicate a request for automatic content recognition (ACR) of an Internet-based streaming version of the over-the-air radio broadcast; and receive metadata associated with the over-the-air radio broadcast in response to the request and initiate transmission of the metadata to the radio broadcast receiver.

Abstract: A system comprises an intermediate communication platform that provides an interface to an Internet network; and a first server including: a port operatively coupled to the intermediate communication platform, processing circuitry, and a service application for execution by the processor. The service application is configured to: receive audio content recognition information from a first radio receiver of multiple radio receivers via the intermediate communication platform, wherein the audio content recognition information identifies audio content received by the first receiver in a radio broadcast; determine audio metadata associated with the received audio content recognition information; and send the audio metadata to the multiple radio receivers via the intermediate communication platform.

Abstract: A system and method for managing the delivery of targeted content. When a user desires to opt-out of receiving targeted content, the user registers with a do-not-target (DNT) registry and is issued a DNT cookie. The DNT cookie is a domain cookie that is stored on a user network access device. A provider of targeted content may look for the DNT cookie stored on the user's network access device. When the DNT cookie is not found, then the provider may deliver targeted content to the user. When the DNT cookie is found, then the provider may not deliver targeted content to the user. A Web site may offer the user an “override” cookie that allows that Web site to provide targeted content, or selected targeted content, even when the user has a DNT cookie. Alternatively, a DNT header can be added to a Web page request that indicates that the user does not want to receive targeted content. The DNT header may be overridden by an override cookie.

Abstract: Methods and apparatus for providing protected content to subscribers of a managed (e.g., MSO) network via a content source accessible via an internetwork such as the Internet. In one embodiment, a user accesses a programmer website website, and requests content. The programmer determines whether the requesting user is permitted to access the content, and what rights or restrictions are associated with the user. This includes authenticating the user as a subscriber of the MSO, and determining the subscriber's subscription level. In another embodiment, a user's account with the MSO and programmer may be federated, thus a given user will have MSO-specific information regarding its identity (such as login information, GUID, etc.) and/or information regarding subscription level and service details, stored at the programmer. Messages received from the MSO representing permission for the user to access content may also be stored at the programmer site for later reference.

Abstract: A system comprises a first server including a port, a memory, a processor operatively coupled to the port and memory, and a service application for execution by the processor. The service application is configured to: receive identification information related to an over-the-air radio broadcast via the port of the first server, wherein the identification information is transmitted to the first server using a radio broadcast receiver remote from the first server, communicate a request for automatic content recognition (ACR) of an Internet-based streaming version of the over-the-air radio broadcast; and receive metadata associated with the over-the-air radio broadcast in response to the request and initiate transmission of the metadata to the radio broadcast receiver.

Abstract: Methods and apparatus for providing protected content to subscribers of a managed (e.g., MSO) network via a content source accessible via an internetwork such as the Internet. In one embodiment, a user accesses a programmer website, and requests content. The programmer determines whether the requesting user is permitted to access the content, and what rights or restrictions are associated with the user. This includes authenticating the user as a subscriber of the MSO, and determining the subscriber's subscription level. In another embodiment, a user's account with the MSO and programmer may be federated, thus a given user will have MSO-specific information regarding its identity (such as login information, GUID, etc.) and/or information regarding subscription level and service details, stored at the programmer. Messages received from the MSO representing permission for the user to access content may also be stored at the programmer site for later reference.

Abstract: Methods and apparatus for providing protected content to subscribers of a managed (e.g., MSO) network via a content source accessible via an internetwork such as the Internet. In one embodiment, a user accesses a service provider portal (e.g., website), and requests content. The service provider determines whether the requesting user is permitted to access the content, and what rights or restrictions are associated with the user. This includes authenticating the user as a subscriber of the MSO, and determining the subscriber's subscription level. In another embodiment, a user's account with the MSO and service provider may be federated, thus a given user will have MSO-specific information regarding its identity (such as login information, GUID, etc.) and is able to perform a single sign on to request and receive content.

Abstract: A system and method for determining entitlement to content residing on a server. A subscriber account with a multi-channel video program distributor (MVPD) includes subscription information indicative of the services provided by the MVPD to the subscriber. A computing device operated by the subscriber sends a request for access to content controlled by the MVPD. The request is received by the MVPD and forwarded to an entitlements server. The entitlement server sends an access granted message to the MVPD when the subscriber is entitled to receive the requested content. The IP address of the subscriber computing device is used to determine whether the computing device is connected to the network via a network access device authorized by the MVPD. The “on-net” or “off-net” status of the computing device may be used to determine whether the subscriber receives the requested content and/or a quality of service level applied to the content.

Abstract: Embodiments described herein relate to apparatus for temperature modulation of samples. Generally, aspects of the disclosure provide for a portable cooling and heating apparatus which enables a user to visualize a sample during cooling or heating. In one embodiment, the apparatus include a sample block, a plurality of thermoelectric modules coupled to the sample block, and a cooling block coupled to the plurality of thermoelectric modules. In another embodiment, the cooling block is in fluid communication with a fluid reservoir. Other embodiments utilize various insulating materials to influence thermal conductivity between the sample block and the cooling block to provide for enhanced temperature control and modulation.

Abstract: Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.