Abstract: Processes of catalytically pyrolyzing solid hydrocarbonaceous materials in a downflow fluid bed reactor and regenerating the catalyst in an upflow fluidized bed reactor are described. Systems and compositions useful in the catalytic pyrolysis of plastics are also described.

Abstract: Pyridazine compounds for inhibiting NaV1.8 and methods for treating a condition, disease, or disorder associated with an increased NaV1.8 activity or expression are disclosed.

Abstract: The invention relates to a nanostructured delivery system comprising at least one polymer and/or at least one lipid and at least one polymethine dye, for use in treating a subject suffering from an adenocarcinoma comprising adenocarcinoma cells with a gene expression alteration in one or more SLCO genes. Therein, the at least one polymethine dye mediates targeted transport of the nanostructured delivery system into said adenocarcinoma cells. The invention relates further to a pharmaceutical composition comprising the nanostructured delivery system. The invention also relates to a method for targeted transport into neoplastic tissue using the nanostructured delivery system and to a use of the nanostructured delivery system or of the pharmaceutical composition of the invention for detection by fluorescence based on the accumulation of said system or composition in neoplastic tissues or cells.

Abstract: In some examples, a pressure reducing valve includes a valve body defining a defining a flow path and a restricting element within the flow path. A sensing element is configured to modify a position of the restricting element in the flow path. A pressure chamber is configured to transmit a force to the sensing element based on the pressure of a fluid within the pressure chamber. An energy accumulator is in fluid communication with the pressure chamber. The pressure reducing valve includes control circuitry configured to enable a fluid to flow into or discharge from the pressure chamber to alter the pressure in the pressure chamber.

Abstract: Creating an effective system and/or method for providing right-sized in-home care requires solving a unique logistics problem: how to optimize a fleet of disparate mobile care resources to geographically distributed and disparate patients, each with an individualized healthcare need. The integrated mobile care unit dispatching tool disclosed herein may schedule and proactively re-schedule in-home care using mobile care units. The mobile care unit dispatching tool accounts for an array of disparate mobile care resources (e.g., different specializations, or a lack of any specialization) and disparate patient needs, any or all of which may change over time, to create and maximize the value of patient schedules for treatment.

Abstract: Composition and methods to prevent, inhibit or treat one or more symptoms of cystic fibrosis are provided.

Abstract: Methods for assessing the result of a surface treatment carried out on a workpiece by particle blasting are disclosed. It is generally common to known automatic methods that they directly determine the covered portion of the surface. Proceeding from the usual definition of the usual 98% degree of coverage as “completely blasted” results in an error in the determination of the corresponding area of 1% to a distortion of the measurement result by 0.98%. In the disclosed method measuring points are identified as not hit by a particle of the particle beam when both a detected surface level is above a level located about a predetermined height threshold value lower than a target level, and a detected gradient falls below a predetermined gradient threshold value.

Abstract: The invention relates to a method for controlling a prosthetic foot (10) which has an upper part (11) with a fastening element (13) for a proximal prosthetic component (20) and a foot part (12) mounted thereon so as to be pivotable about a pivot axis (15), comprising a resistance device (40) used to counteract a pivoting movement of the foot part (12) relative to the upper part (11) by way of an adjustable resistance (Am), and comprising a control device (70) which is coupled to the resistance device (40) and to at least one sensor (60) and by means of which the resistance to pivoting is set on the basis of sensor data, wherein ground contact of the foot part (12) with the ground is determined by way of at least one sensor (60), wherein the relative spatial position of the foot part (12) and/or of the upper part (11) is determined using an inertial measurement unit (30) and wherein the resistance (Am) to pivoting is altered on the basis of the presence or lack of ground contact and the determined relative spa

Abstract: A method for configuring quality-of-service quantities in a network including a first network segment has a first gateway as a network subscriber and each of multiple second network segments has a second gateway as a network subscriber. The first gateway and the second gateways are logically set up in a tree structure having multiple stages. Each gateway in a stage is connected in a data-conducting manner to precisely one gateway in a stage situated below. The first gateway forms the lowest stage. Each gateway makes a quality-of-service quantity available for the forwarding of data. The method includes: an addressed gateway receiving a quality-of-service request from a requesting network subscriber; checking whether the addressed gateway has a sufficient free quality-of-service quantity; if not, rejecting the quality-of-service request by a negative reply; if so, forwarding the quality-of-service request to the gateway in the stage situated below.

Abstract: A radar target emulator with a superimposition apparatus, having a first input provided to receive a first signal, a second input provided to receive a second signal, a first attenuation device that is connected to the first input in signal-carrying fashion and configured to attenuate the first signal, in particular to a predetermined extent, and to provide a first attenuated signal, a second attenuation device that is connected to the second input in signal-carrying fashion and configured to attenuate the second signal, in particular to a predetermined extent, and to provide a second attenuated signal, an addition device that is configured to add the first attenuated signal and the second attenuated signal and to output a corresponding output signal.

Abstract: The present invention relates to an apparatus and a method for converting a radar signal for further signal processing in a test bench with a radar target emulator as well as a test bench having such an apparatus. A divider assembly preferably comprises a divider device configured to reduce a frequency and a bandwidth of the radar signal by a first factor for the further signal processing. A multiplier assembly preferably comprises a multiplier device configured to increase a frequency and a bandwidth of the radar signal by the first factor subsequent the further signal processing.

Abstract: An adjusting device is provided for positioning an object. The adjusting device includes a base and a supply line. The base is configured to move an object that is connectable to the base in the connected state along a path of motion in a position-controlled manner. The supply line supplies the energy and/or signal transmission to and/or from the base. The supply line is coupled to the base in a reversibly detachable manner.

Abstract: A method for operating a communications system, in particular a communications system based on software-defined networking, which has at least one network infrastructure component, in particular an SDN switch, and at least one communications device, the network infrastructure component being developed for forwarding data to and/or from the at least one communications device. The method includes the following steps: allocating the communications device to at least one security zone; specifying at least one forwarding rule for forwarding data by the network infrastructure component to and/or from the communications device, the specification of the forwarding rule taking place under consideration of the security zone.

Abstract: The invention relates to a double-leaf vehicle door device comprising at least the following: two door leaves, each of which can be moved between an open position and a closed position in the form of a respective end position and into any intermediate position between the first open position and the first closed position, wherein a first movement of the first door leaf between the first open position and the first closed position is carried out without mechanically coupling the first door leaf to the second door leaf in contrast to a second movement of the second door leaf between the second open position and the second closed position, and a common locking device is provided which locks the first door leaf in the closed position when the first door leaf is located in the closed position and which locks the second door leaf in the closed position when the second door leaf is in the closed position.

Abstract: Disclosed is a method for reducing the electromagnetic interference produced during the switching to the on state of a transistor for switching a quasi-resonant DC-DC voltage converter. The method includes the steps of: the transistor being initially controlled so as to be in the on state on the basis of a first control current, controlling the driving module by way of the control module so that the driving module switches the transistor to the off state at a first instant; and triggering the timer from the first instant, and, if the timer reaches a predefined duration threshold, controlling, by means of the driving module, the transistor so as to be in the on state on the basis of a second control current the intensity of which is lower than the intensity of the first control current.

Abstract: A device and method for operating a communications network in a vehicle, or for operating an industrial communications network; a control entity for the communications network, in particular, a software-defined networking controller, determining a countermeasure after detection of an attack; an infrastructure component being configured as a function of the countermeasure, in particular, by setting at least one filtering, blocking or forwarding rule; and at least one data stream from or to at least one other infrastructure component being isolated by the infrastructure component, in a portion of the communications network; or at least one data stream to or from an end node being isolated by the infrastructure component, in a portion of the communications network.

Abstract: A switching device for a radar target emulator is provided comprising: at least one first switch arrangement and a second switch arrangement, each having a branching device designed to receive a first input signal and diverge it into a branch signal and a first output signal, a switch adapted to transmit the branch signal in a first switching state within the switch arrangement and to not transmit in a second switching state, and adding means designed to emit the signal transmitted in the first switching state of the switch, at least as components of a second output signal. The first switching arrangement and the second switching arrangement are interconnected in such a way that a first input signal of the second switching arrangement comprises a first output signal of the first switching arrangement, or a second input signal of the second switching arrangement comprises a second output of the first switching arrangement.

Abstract: A vehicle sliding door device includes at least one sliding door which can be moved in a movement direction or a pivoting and sliding door which can be pivoted in a pivoting direction and which can be moved in a movement direction relative to a door frame that has a door opening, and a locking device for locking the at least one sliding door at least in the closed position that includes an emergency unlocking device, by which the at least one sliding door which is locked in the closed position can be unlocked in the event of an emergency. An emergency opening device is provided for at least partly opening the at least one sliding door or the pivoting and sliding door in the event of an emergency in an emergency unlocking state.

Abstract: A method and device for operating a network component and a control instance in a software-defined networking communication infrastructure. The software-defined networking communication infrastructure is switched from an operation according to a first strategy for forwarding time-critical data streams in network components of the communication infrastructure to an operation according to a second strategy for forwarding time-critical data streams in network components as a function of at least one trigger signal, the at least one trigger signal being received in an operation according to the first strategy from a control instance in a unicast message or in a broadcast message.

Abstract: Disclosed is a method for reducing the electromagnetic interference produced during the switching to the on state of a transistor for switching a quasi-resonant DC-DC voltage converter. The method includes the steps of: the transistor being initially controlled so as to be in the on state on the basis of a first control current, controlling the driving module by way of the control module so that the driving module switches the transistor to the off state at a first instant; and triggering the timer from the first instant, and, if the timer reaches a predefined duration threshold, controlling, by means of the driving module, the transistor so as to be in the on state on the basis of a second control current the intensity of which is lower than the intensity of the first control current.