Patents by Inventor MICHAEL A. GALLUPPI

MICHAEL A. GALLUPPI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALTERNATIVE CANNULA CONFIGURATIONS TO CONTROL FLUID DISTRIBUTION IN TISSUE
    Publication number: 20230114337
    Abstract: A cannula for subcutaneous dispensing of medicaments, wherein the cannula has a cannula wall, a distal end and a proximal end and wherein the cannula comprises a single orifice in the cannula wall, proximal to the distal end of the cannula or two or more orifices in the cannula wall, proximal to the distal end of the cannula.
    Type: Application
    Filed: February 9, 2021
    Publication date: April 13, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Scott BROWN, John B. CLINE, Michael GALLUPPI, Jeffrey C. GIVAND, Guangli HU, Steven Carl PERSAK, Wail RASHEED
  • DRY POWDER INHALER WITH DOSE DEPLETION EVALUATION
    Publication number: 20170095625
    Abstract: A dry powder inhaler is provided herein which includes a dose chamber having a staging area configured to accommodate an inhalable dose of active pharmaceutical agent. A nozzle is provided having a discharge aperture with an inhalation channel communicating the staging area with the discharge aperture. The inhalation channel is configured such that sufficient negative pressure applied to the discharge aperture draws a dose from the staging area towards the discharge aperture. An arrangement is provided for evaluating the level of depletion of a dose from the staging area. Advantageously, the subject invention allows for evaluating physical depletion of a staged dose so as to recognize the level of delivery thereof.
    Type: Application
    Filed: May 29, 2015
    Publication date: April 6, 2017
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: PETER A. BASILE, MICHAEL GALLUPPI, MIKHAIL GOTLIBOYM, CHRISTOPHER GRANELLI, SCOTT BROWN
  • Drug products, dry powder inhalers and polyflux collider arrangements
    Patent number: 9174012
    Abstract: This disclosure relates to dry powder inhalers and drug products and, more particularly to polyflux colliders useful for de-agglomerating dry powder in dry powder dispensers. Various embodiments provide drug products, dry powder inhalers and polyflux collider arrangement. With various embodiments of the present invention, a polyflux collider is provided which utilizes colliding streams of dry powder to provide desirable de-agglomerating capability for dry powder dispensers.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: November 3, 2015
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: Michael Galluppi, Scott Brown, Peter A. Basile
  • DRY POWDER INHALER FOR DELIVERING MULTIPE AGGLOMERATE FORMULATIONS
    Publication number: 20150020806
    Abstract: Various embodiments provide drug products and dry powder inhalers. With various embodiments of the present invention, a de-agglomeration chamber and by-pass channel are provided which allow for various de-agglomerating capabilities for dry powder dispensers.
    Type: Application
    Filed: July 16, 2014
    Publication date: January 22, 2015
    Inventors: MICHAEL A. GALLUPPI, ALEKSANDR ZUYEV, ANNANIY BERENSHTEYN, SCOTT C. BROWN
  • DRUG PRODUCTS, DRY POWDER INHALERS AND POLYFLUX COLLIDER ARRANGEMENTS
    Publication number: 20130000639
    Abstract: This invention relates to dry powder inhalers and drug products and, more particularly to polyflux colliders useful for de-agglomerating dry powder in dry powder dispensers. Various embodiments provide drug products, dry powder inhalers and polyflux collider arrangement. With various embodiments of the present invention, a polyflux collider is provided which utilizes colliding streams of dry powder to provide desirable de-agglomerating capability for dry powder dispensers.
    Type: Application
    Filed: November 9, 2010
    Publication date: January 3, 2013
    Inventors: Michael Galluppi, Scott Brown, Peter A. Basile