Abstract: This disclosure describes methods and compositions for protein and peptide sequencing.

Abstract: Provided herein are reaction mixtures, compositions, systems, methods, and kits for assessing enzymatic activity. Aspects of the disclosure include use of a reactant barcoded oligonucleotide (RBO) construct comprising a first oligonucleotide comprising a reaction barcode sequence and a first linker that connects the first oligonucleotide to a first reactant, an amplification construct comprising a second oligonucleotide that is complementary to at least a portion of the first oligonucleotide and a second linker that connects the second oligonucleotide to a second reactant, and a blocking construct, comprising a third oligonucleotide that is complementary to at least a portion of the first oligonucleotide. A rate of reaction product generation may be measured to determine an enzymatic activity of a given enzyme.

Abstract: This disclosure describes methods and compositions for protein and peptide sequencing.

Abstract: Devices, kits, and their methods of use for lysing and/or purifying biological particles, e.g., nuclei are provided. One or more thixotropic layers can be employed in a vessel to purify biological particles. A device with sharp features may be employed to lyse biological particles or the contents thereof.

Abstract: A multi-function communications network includes a front-end communications network in signal communication with a plurality of communication nodes. Each communication node includes a plurality of discrete network elements. One or more network element adapters are in signal communication with a respective network element among the plurality of discrete network elements. A network management system is in signal communication with the network element adapters. The network management system is configured to generate reconfiguration parameters in response to an operating disruption of at least one affected node among the plurality of communication nodes. At least one of the network elements included in the affected node is reconfigured based at least in part on the reconfiguration parameters.

Abstract: A system that allows direct manipulation of numerical parameters while playing games. Vertical columns of physical units are formed into deques that each represent between one and three parameters of the game state at a given time. The game's mechanics are defined as a set of state transitions, each of which map a configuration of units/deques, along with a nonnegative integer input, to a new configuration of units/deques. This new configuration directly represents the resultant game state and parameters thereof, and is naturally subject to further systematic manipulation.

Abstract: This disclosure describes methods and compositions for protein and peptide sequencing.

Abstract: This disclosure describes methods and compositions for protein and peptide sequencing.

Abstract: A multi-function communications network includes a front-end communications network in signal communication with a plurality of communication nodes. Each communication node includes a plurality of discrete network elements. One or more network element adapters are in signal communication with a respective network element among the plurality of discrete network elements. A network management system is in signal communication with the network element adapters. The network management system is configured to generate reconfiguration parameters in response to an operating disruption of at least one affected node among the plurality of communication nodes. At least one of the network elements included in the affected node is reconfigured based at least in part on the reconfiguration parameters.

Abstract: Methods and systems to improve the utilization of rented and owned equipment by accurately and automatically monitoring equipment utilization rates and making recommendations for desired utilization rates and optimal inventory levels based on statistical analysis of actual utilization rates. By making usage recommendations, embodiments of the present invention allow users of the inventive system to purchase and maintain appropriate quantities of movable assets, proactively manage equipment rental costs, and reduce equipment costs and inventory liability. In a medical environment, these benefits also include improved availability and access to items needed for patient care.

Abstract: Devices and methods for removal of fasteners by Electro-discharge Machining (EDM) such that portions of the fastener, such as a flange head, may be separated from other portions of the fastener, such as a shank.

Abstract: The hand-held electro-discharge device to remove boluses of material from a workpiece. In some implementations a conductive electrode and its supporting ground pin are immersed in a dielectric fluid contained in a hood or cavity near or at the electrode's distal tip an removably sealed to a conductive workpiece. A flushing inlet and outlet in fluid communication with said hood provide a flushing fluid, which may also be a dielectric fluid to remove FOD and cool.

Abstract: A control module for an EDM device, comprises: controls for managing power supplied to the EDM device, taking voltage measurements, calculating responses, and controlling advancement of an electrode of the EDM device. The EDM device may include a piezoelectric crystal that electrically in parallel with the voltage applied to a spark gap between the electrode and a workpiece.

Abstract: The hand-held electro-discharge machining fastener removal device of this invention brings an EDM electrode and its supporting ground pin and dielectric fluid structure to a fastener in a workpiece, such as an aircraft fuselage. The hand-held device brings the dielectric fluid, power supply, and control system structure to the fastener in a compact tool to permit EDM machining to be brought to large structures.

Abstract: The hand-held electro-discharge device to remove boluses of material from a workpiece. In some implementations a conductive electrode and its supporting ground pin are immersed in a dielectric fluid contained in a hood or cavity near or at the electrode's distal tip an removably sealed to a conductive workpiece. A flushing inlet and outlet in fluid communication with said hood provide a flushing fluid, which may also be a dielectric fluid to remove FOD and cool.

Abstract: The hand-held electro-discharge machining fastener removal device of this invention brings an EDM electrode and its supporting ground pin and dielectric fluid structure to a fastener in a workpiece, such as an aircraft fuselage. The hand-held device brings the dielectric fluid, power supply, and control system structure to the fastener in a compact tool to permit EDM machining to be brought to large structures.

Abstract: An integrated relay system includes an automotive relay and a terminal interface. The automotive relay includes switching contacts and a casing. The casing at least partially surrounds the switching contacts and includes an aperture. The terminal interface is electrically connected with at least one of the switching contacts and is configured to receive a portion of a fuse. The terminal interface also passes through aperture and extends away from the casing.

Abstract: A system for varying the output of an exterior light of a vehicle having a source of power further includes an exterior vehicle light operatively connected to the source power and a controller for controlling the exterior vehicle light. The controller is coupled between the exterior vehicle light and the source of power and generates a plurality of power output signals to the exterior vehicle light, wherein each of the plurality of power output signals defines a light effect.

Abstract: A projection system having a controller and a plurality of reflective SLMs operatively coupled to the controller to receive image data from the controller. The reflective SLMs arc aligned in series to receive light form a light source and to reflect imaging light correlated to the image data.

Abstract: Apparatus and techniques for enhancing characteristics of electronic projection systems are detailed. Included among the techniques are both superimposition of sub-images and tiling of superimposed images, the combination of which can be advantageous in improving resolution of projected images. Pre-modulators and polarizing beam splitters also may be used as parts of the innovative systems.