Abstract: Provided herein are methods, compositions and articles of manufacture for use in connection with cell therapy involving the administration of one or more doses of a therapeutic T cell composition. The cells of the T cell composition express recombinant receptors such as chimeric receptors, e.g. chimeric antigen receptors (CARs) or other transgenic receptors such as T cell receptors (TCRs). Features of the provided embodiments, including the numbers of cells or units of cells administered and/or the potency of administered cells, provide various advantages, such as lower risk of toxicity in subjects administered the T cell compositions.

Abstract: A neuromodulation system and method. An implantable electrode array comprises a plurality of electrodes. A stimulus source provides neural stimuli delivered via stimulus electrodes to neural tissue to evoke neural responses. Measurement circuitry captures signal windows sensed from the neural tissue subsequent to each stimulus. A control unit controls the neural stimuli according to a stimulus intensity parameter. A processor introduces a perturbation to the parameter from a baseline stimulus intensity. A time series of intensities of the evoked neural responses is obtained. from which a time series of estimates of at least one physiological characteristic of the neural tissue is obtained. Each physiological characteristic being variable as a result of a posture wave. A baseline value of each physiological characteristic is estimated from the time series of estimates of each physiological characteristic.

Abstract: The present disclosure includes dipole line trap system, a method for tuning a natural frequency of a dipole line trap system, and seismometer. One embodiment of the dipole line trap system may comprise a first axis unit. The first axis unit may comprise a first group of at least three cylindrical diametric magnets mounted in parallel around a first open region, and a first diamagnetic object in the first open region. In some embodiments, the first axis unit may comprise four cylindrical diametric magnets mounted in parallel around the first open region. In some embodiments, the first axis unit may have a natural frequency of less than 1 Hz.

Abstract: Embodiments are directed to compositions and methods for treating viral infections.

Abstract: Misaligned bones on opposite sides of a joint are aligned using a first rigid extension securable to one of the misaligned bones using a particular surgical approach, and a second rigid extension having a contacting surface positionable in contact with the other the two misaligned bones from the same surgical approach. The first and second rigid extensions are moved with respect to each other using a lever, whereby a pulling force is exerted on one of the bones, and a pushing force on the other, thereby aligning the first and second misaligned bones.

Abstract: A single handheld multimeter device includes two or more independent measurement channels that are completely electrically separated and independent from one another. Each measurement channel has its point of reference, typically configured to be coupled to the ground. Measurements by the two or more independent measurement channels can be conducted concurrently, and the measurement results of the two channels can be processed and displayed together.

Abstract: A system and device for use in open or minimally invasive surgical procedures, such as a bone implant fixation procedure. The device is configured to perform various functions during a bone implant fixation procedure, including performing at least one of: penetration of a bone to form a hole or opening for receipt of a screw; neuromonitoring, in cooperation with a neuromonitoring device, of the hole during, or post-, formation of the hole so as to sense any nearby nerves adjacent to the hole that may be in the path of a screw, or otherwise affected, when a screw is placed within the hole; neurostimulation, in cooperation with a neuromonitoring device, of nerves adjacent to the hole during, or post-, formation of the hole; and measuring of a depth of the hole and providing a digital measurement of the depth to assist the surgeon in selecting the appropriate length of screw.

Abstract: Systems and methods are described herein for generating compliance indicators on a user interface corresponding to maturity levels of a continuous integration/continuous deployment system. A server captures compliance data corresponding to development status associated with a software application comprising newly-added source code. The server determines whether a plurality of maturity levels of a continuous integration system are completed for the software application based upon the captured compliance data. The server generates a plurality of compliance indicators, each of the compliance indicators corresponding to one of the maturity levels that is completed. The server generates for display the generated compliance indicators on a user interface of a user device communicatively coupled to the server.

Abstract: Compounds, particles, and cathode active materials that include lithium, cobalt, manganese, nickel, aluminum, and other elements can be used in lithium ion batteries. The cathode active materials include compounds having the general Formula (I): compound represented by Formula (I): Li?CO1-x-y-zMewMnxNiyAlzO?, as well as Formula (II): Li?CO1-s-u-vMesMntNiuAlyO?.

Abstract: A crossflow filter device for filtering a pressurised feed liquid is provided. The crossflow filter device comprises: a filter membrane; a flow channel for the pressurised feed liquid which extends in a path over a retentate surface of the membrane such that the direction of flow in the channel is tangential to the retentate surface, and a filtrate derived from the feed liquid passes through the membrane leaving retentate liquid in the flow channel; and a collection chamber for the filtrate formed on an opposite, filtrate surface of the membrane. The crossflow filter device further comprises a sealed housing having a retentate side and a filtrate side which enclose therebetween the flow channel, the filter membrane and the collection chamber. The crossflow filter device further comprises, flow channel guide walls provided at an inner surface of the retentate side of the housing.

Abstract: A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions that, when executed on the one or more processors, cause the one or more processors to perform operations: receiving, from electronic devices of users, orders for pickup at a location during a first window of time; determining whether a congestion level at the location exceeds a predetermined level of congestion during the first window of time based on congestion data of the location; and after the congestion level at the location is determined to not exceed the predetermined level of congestion during the first window of time, transmitting a pickup request to cause an electronic device of a pickup driver to display the pickup request, wherein at least one order is fulfilled. Other embodiments are described.

Abstract: In a novel method and composition of heterodissemination technology, small mammals attracted to a food bait in a dissemination station acquire electrostatically charged acaricide laden microspheres that can he polymeric nano-porous microspheres loaded with one or more chemical acaricides, or calcium or sodium alginate microspheres that encapsulate an entomopathogen. Microspheres loaded with either type of acaricide kill ticks on the small mammals that acquire them, and when shed along small mammal pathways and in their dens, they also kill free-living ticks.

Abstract: Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and perform: receiving, from one or more electronic devices of one or more users, one or more orders for pickup at a location during a first window of time; at a first time during the first window of time, determining when a designated pickup area at the location exceeds a predetermined level of congestion using: (1) continuously received mobile check-ins at the location; and (2) congestion data of the designated pickup area at the location; and when the designated pickup area at the location does not exceed the predetermined level of congestion during the first window of time, as determined at the first time, causing a pickup electronic device of a pickup to display a pickup request at the location to fulfill at least one order of the one or more orders during the first window of time. Other embodiments are disclosed herein.

Abstract: A system including one or more processors and one or more non-transitory storage media storing computing instructions that, when executed on the one or more processors, cause the one or more processors to perform operations including: receiving an order list for delivery at a delivery address; determining an estimated order collection time; continuously monitoring, in real-time, a respective location of each delivery driver of one or more delivery drivers of at least one delivery service by receiving the respective location of each delivery driver of the one or more delivery drivers from a respective delivery driver electronic device of each delivery driver; and instructing a first delivery driver of the one or more delivery drivers to pick up one or more items in the order list and deliver the one or more items to the delivery address. Other embodiments are disclosed herein.

Abstract: Systems and methods are presented for generating recommendations using multi-level social network analysis of user behavior. In some embodiments, the system receives a set of user interactions, from a plurality of users, performed on a set of data objects; generates a set of associations between the set of data objects; and identifies a set of data object clusters indicative of the set of associations. The system generates an organization of the set of data objects based on the set of associations and the set of data object clusters and causes presentation of a plurality of data objects of the set of data objects on a user interface of a user device based on the organization.

Abstract: A system comprising one or more processors and one or more non-transitory computer-readable media storing computing instructions that, when executed on the one or more processors, cause the one or more processors to perform operations comprising: initiating a return request for one or more items; display on the first electronic device one or more windows of time for a driver to arrive at an address; receiving a selection of at least one of the one or more windows of time for the driver; assigning the driver to pick up the one or more items from the address; causing a second electronic device of the driver to display the address; and receiving one or more acceptance scans for the one or more items from the second electronic device of the driver. Other embodiments are disclosed.

Abstract: A system comprising one or more processors and one or more non-transitory computer-readable media storing computing instructions that, when executed on the one or more processors, cause the one or more processors to perform operations comprising: determining, using a predictive analysis, an estimated collection time to collect one or more items of an order; receiving a mobile check-in from an electronic device indicating that a pickup is en-route to pick-up the order from the store; tracking a location of the pickup; periodically determining an estimated travel time for the pickup to travel to the store from the location, as tracked; and transmitting instructions for the one or more employees of the store to begin collecting the one or more items of the order on a store interface Other embodiments are disclosed herein.

Abstract: Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and perform: receiving a request from a user; determining, using a regression analysis, an estimated order collection time for a collection of the one or more items of the order list by at least one collector; continuously monitoring a respective location of each respective delivery driver; continuously determining a respective estimated order pickup time for each respective delivery driver; and instructing the first delivery driver of the one or more delivery drivers to pick up the one or more items and deliver the one or more items to the delivery address. Other embodiments are disclosed herein.

Abstract: Systems and methods including one or more processing modules and one or more non-transitory storage modules storing computing instructions configured to run on the one or more processing modules and perform acts of receiving a return request for an item from a customer electronic device of a customer, determining that the return request is available for a pickup return option for (1) pickup, by a driver, of the item at an address associated with the customer and (2) transportation, by the driver, of the item from the address to the store, and, if the customer selects a pickup return option: assigning the driver to pick up the item from the address and transport the item to the store, receiving a return scan for the item from a store electronic device at the store or from a driver electronic device, and initiating a refund to the customer for the item.

Abstract: The present disclosure includes dipole line trap system, a method for tuning a natural frequency of a dipole line trap system, and seismometer. One embodiment of the dipole line trap system may comprise a first axis unit. The first axis unit may comprise a first group of at least three cylindrical diametric magnets mounted in parallel around a first open region, and a first diamagnetic object in the first open region. In some embodiments, the first axis unit may comprise four cylindrical diametric magnets mounted in parallel around the first open region. In some embodiments, the first axis unit may have a natural frequency of less than 1 Hz.