Abstract: Aspects of the present disclosure are directed to a collaborative workspace for an artificial reality (XR) environment. Some implementations can take advantage of the capabilities of XR systems when working on collaborative large documents, such as design sheets and spreadsheets. For example, when a user launches a link to a large design sheet in XR, the workspace can show both a large view of the entire collaborative design space, as well as a personal viewport into the area of the design space that the user is working on. The workspace can include a number of collaboration controls, such as being able to follow someone else's viewport, filtering of the large view to include only the area of the sheet where a user's team is working, replaying a user's edits or view while moving around the design sheet, etc.

Abstract: In some embodiments, the present disclosure pertains to an injectable shear-thinning composition that comprises (a) one or more types of polymers, (b) one or more types of microparticles and (c) water. In some embodiments, the present disclosure pertains to a kit that comprises (a) one or more containers that contain an injectable shear-thinning composition that comprises one or more types of polymers, one or more types of microparticles and water and (b) a delivery device. In some embodiments, the present disclosure pertains to a medical procedure comprising administering to a subject an injectable shear-thinning composition that comprises one or more types of polymers, one or more types of microparticles and water.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt and/or hydrate and/or prodrug of the compound) that modulate (e.g., agonize) the apelin receptor (also referred to herein as the APJ receptor; gene symbol “APLNR”). This disclosure also features compositions containing the same as well as other methods of using and making the same. The chemical entities are useful, e.g., for treating a subject (e.g., a human) having a disease, disorder, or condition in which a decrease in APJ receptor activity (e.g., repressed or impaired APJ receptor signaling; e.g., repressed or impaired apelin-APJ receptor signaling) or downregulation of endogenous apelin contributes to the pathology and/or symptoms and/or progression of the disease, disorder, or condition.

Abstract: A disclosed server system for dynamically generating and serving content for presentation across different channels can perform the following operations: receive a request from a client device for a subset of content elements, the request designating a desired channel for presenting content in a page, identify the subset having at least one content attribute that satisfies one or more subset creation criteria indicating a category identifier for a slot in a page template used for generating the page, dynamically generate the subset by: for each content element in the subset, dynamically adjusting presentation of the singular instance of the content element based on presentation requirements of the desired channel, the singular instance being commonly used across all device interface types, and serve the subset of the content elements to the client device, which includes the singular instances of the content elements dynamically adjusted for presentation in the desired channel.

Abstract: Aqueous liquid embolic compositions as well as method for making and using aqueous liquid embolic compositions are disclosed. An example aqueous liquid embolic composition may include a di-block or tri-block copolymer including a hydrophobic monomer block and a charged (polycationic or polyanionic) block. The charged (polycationic or polyanionic) block may include one or more anions. The aqueous liquid embolic composition may also include templating agent.

Abstract: Aqueous liquid embolic compositions, for example formed from amino acids, as well as method for making and using aqueous liquid embolic compositions are disclosed. An example aqueous liquid embolic composition may include a di-block or tri-block copolymer including a charged block and a hydrophobic block. The aqueous liquid embolic composition may also include templating agent.

Abstract: A controller for an injection molding system is in communication with a melt flow control unit, a gas assist control unit, and a gas counter pressure control unit. The controller can effect real-time adjustments to gas assist pressure and/or gas counter pressure as a function of melt pressure or flow front position.

Abstract: Medical systems are described, including a medical system that includes a sheath and a catheter. The sheath is configured to be positioned within a urethra of a patient. A proximal portion of the sheath includes a port configured to receive one or more fluids. The catheter is insertable into the sheath and configured to be movably positioned within the sheath in the urethra. A distal portion of the catheter includes one or more ultrasound transducers configured to perform ultrasound imaging of at least a portion of a prostate of the patient.

Abstract: A product includes a three-dimensional scaffold structure having an open cell geometry with interconnected channels for allowing continuous communication throughout a volume of the scaffold structure. The scaffold structure is configured to enhance mechanical strength of an energetic material. A fuel material is present in the scaffold structure and/or a second material is coupled to the scaffold structure. The fuel material is configured to increase an output of energy release relative to an output of energy release from the scaffold structure having the fuel material not present.

Abstract: A method for operating an agricultural vehicle, the method including: generating an overdrive torque at a drive wheel motor of at least one ground drive system; transmitting the overdrive torque to the engine via a hydraulic ground drive circuit and a ground drive pump, to thereby bias the engine to operate at an increased rotation speed; measuring an engine rotation speed; comparing the engine rotation speed to a threshold value; and upon determining that the engine rotation speed satisfies the threshold value, operating the auxiliary hydraulic component of an auxiliary hydraulic system to generate a braking torque at a respective auxiliary pump, and transmitting each the braking torque to the engine to bias the engine to operate at a decreased rotation speed. An agricultural vehicle having a control system to perform the method is also provided.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt and/or hydrate and/or prodrug of the compound) that modulate (e.g., agonize) the apelin receptor (also referred to herein as the APJ receptor; gene symbol APLNR). This disclosure also features compositions containing the same as well as other methods of using and making the same. The chemical entities are useful, e.g., for treating a subject (e.g., a human) having a disease, disorder, or condition in which a decrease in APJ receptor activity (e.g., repressed or impaired APJ receptor signaling; e.g., repressed or impaired apelin-APJ receptor signaling) or downregulation of endogenous apelin contributes to the pathology and/or symptoms and/or progression of the disease, disorder, or condition.

Abstract: Embodiments herein relate to fenestrations exhibiting coastal impact performance. In an embodiment, a fenestration unit includes a frame assembly forming a first lower corner and a second lower corner. A first sill corner bracket can fit on a top of a sill and extend from the first lower corner partway along the top of the sill and partway along one side jamb of the frame assembly. A second sill corner bracket can be configured to fit on the top of the sill and extend from the second lower corner partway along the top of the sill and partway along the other side jamb. A bottom sash can include a bottom rail defining a channel to receive at least a portion of the first corner bracket and the second corner bracket therein when the bottom sash is in the closed position. Other embodiments are also included herein.

Abstract: This disclosure relates to LPA antagonists of Formula (I): including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt and/or hydrate and/or prodrug of the compound) that modulate (e.g., agonize) the apelin receptor (also referred to herein as the APJ receptor; gene symbol “APLNR”). This disclosure also features compositions containing the same as well as other methods of using and making the same. The chemical entities are useful, e.g., for treating a subject (e.g., a human) having a disease, disorder, or condition in which a decrease in APJ receptor activity (e.g., repressed or impaired APJ receptor signaling; e.g., repressed or impaired apelin-APJ receptor signaling) or downregulation of endogenous apelin contributes to the pathology and/or symptoms and/or progression of the disease, disorder, or condition.

Abstract: Examples described herein relate to a securing sub-system. The securing sub-system includes a lever and a cam assembly engaged with the lever. The cam assembly is movable due to a pivotal movement of the lever and includes a cam body, a cantilevered arm, and a load support member. The cantilevered arm extends from the cam body and is deformable when the cantilevered arm contacts a restrictive structure. The load support member disposed on the insertion cam. A portion of the load support member is offset from an open end of the cantilevered arm to limit deformation of the cantilevered arm. Further, some examples described herein relate to a securing system including a plurality of securing sub-systems coupled via a synchronous movement link is also presented. Moreover, certain examples described herein relate to a computing system including at least one such securing sub-system.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt and/or hydrate and/or prodrug of the compound) that modulate (e.g., agonize) the apelin receptor (also referred to herein as the APJ receptor; gene symbol APLNR). This disclosure also features compositions containing the same as well as other methods of using and making the same. The chemical entities are useful, e.g., for treating a subject (e.g., a human) having a disease, disorder, or condition in which a decrease in APJ receptor activity (e.g., repressed or impaired APJ receptor signaling; e.g., repressed or impaired apelin-APJ receptor signaling) or downregulation of endogenous apelin contributes to the pathology and/or symptoms and/or progression of the disease, disorder, or condition.

Abstract: Embodiments herein relate to fenestrations exhibiting coastal impact performance. In an embodiment, a fenestration unit includes a frame assembly forming a first lower corner and a second lower corner. A first sill corner bracket can fit on a top of a sill and extend from the first lower corner partway along the top of the sill and partway along one side jamb of the frame assembly. A second sill corner bracket can be configured to fit on the top of the sill and extend from the second lower corner partway along the top of the sill and partway along the other side jamb. A bottom sash can include a bottom rail defining a channel to receive at least a portion of the first corner bracket and the second corner bracket therein when the bottom sash is in the closed position. Other embodiments are also included herein.

Abstract: Embodiments herein relate to fenestrations, such as windows and doors, exhibiting coastal impact performance. In a first aspect, an impact-resistant fenestration unit can be included having a frame and a bottom sash. The bottom sash can have a bottom rail, a check rail, and opposed stiles and can be configured to pivot inward away from the frame assembly such that the check rail moves away from the frame assembly. A first side bracket can define a cavity to receive a portion of a bolt from a sash tilt bolt assembly. The first side bracket can be mounted on one of the two opposed side jambs at a height corresponding to a position of the check rail when the bottom sash can be in a closed position. The bolt can include a metal inner support member and a polymeric overmold portion. Other embodiments are also included herein.

Abstract: Embodiments herein relate to fenestrations, such as windows and doors, exhibiting coastal impact performance. In a first aspect, an impact-resistant fenestration unit can be included having a frame assembly including a sill, a head jamb, and two opposed side jambs. A bottom sash can be included having a bottom rail, a check rail, and two opposed stiles. A first corner key can be configured to engage the bottom sash at a first lower corner. The first corner key can include a support arm extending in a first direction onto or into a first stile of the two opposed stiles. A first reinforcement member disposed on or within the first stile. The first reinforcement member can include a first end and a second end. The first end can overlap a portion of the support arm of the first corner key. Other embodiments are also included herein.