Patents by Inventor Michael A. Hoffmann

Michael A. Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050176678
    Abstract: The invention concerns oligosaccharides and polysaccharides as well as the use of these oligosaccharides and/or polysaccharides, which contain the sugar unit N-acylglucosamine or N-acylgalactosamine for the production of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with said oligosaccharides and/or polysaccharides, which imitate the common biosynthetic precursor substance of heparin, heparan sulphates and chitosan. The invention further describes methods for producing said oligosaccharides and/or polysaccharides and discloses various possibilities of using hemocompatibly coated surfaces. The invention relates particularly to the use of said oligosaccharides and/or polysaccharides on stents with at least one according to invention deposited hemocompatible coating, which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.
    Type: Application
    Filed: April 15, 2003
    Publication date: August 11, 2005
    Inventors: Roland Horres, Marita Linssen, Michael Hoffmann, Erika Hoffmann, Donato Di Baise, Volker Faust
  • Publication number: 20050150480
    Abstract: In an arrangement for handling the fuel in a common rail fuel injection system of an internal combustion engine, wherein fuel is supplied from a tank via a fuel delivery line including a first fuel filter, a low-pressure pump arranged upstream from the first fuel filter and a high pressure pump arranged downstream of the first fuel filter to a high pressure fuel rail from which the fuel is distributed to the cylinder of the engine, a bypass line extends from the high pressure fuel rail to the fuel delivery line and includes a second fuel filter and a heat exchanger which is operatively connected to a cooling circuit of an air conditioning system or to a cooling circuit of the internal combustion engine.
    Type: Application
    Filed: January 14, 2005
    Publication date: July 14, 2005
    Inventors: Michael Hoffmann, Magnus Korte, Ulrich Rieger
  • Publication number: 20050129731
    Abstract: The invention relates to medical products with at least one biocompatible biostable polysulfone coating with which the elution kinetics of the incorporated and/or deposited at least one antiproliferative, antiinflammatory, antiphlogistic and/or antithrombotic active agent can be controlled via the admixing of at least one hydrophilic polymer in a suitable amount and as well as an local separation of different active agents and active agent combinations respectively can be achieved by means of the layer system of biostable polymers, methods of manufacturing these medical products as well as their use especially in the form of stents for prevention of restenosis.
    Type: Application
    Filed: November 3, 2004
    Publication date: June 16, 2005
    Inventors: Roland Horres, Michael Hoffmann, Volker Faust, Erika Hoffmann, Donato Di Biase
  • Patent number: 6903544
    Abstract: In order to provide a position transducer device for detecting the position of a position transmitter, comprising a housing extending in a longitudinal direction and a measuring sensor arranged in the housing and extending parallel to the longitudinal direction, the position transmitter being coupled to this measuring sensor without contact, which is variable in its use for a user it is suggested that an outer surface of the housing be designed such that it can be enclosed at least partially by a fixing receiving means for fixing it to an application and that the housing can be rotated in the fixing receiving means.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: June 7, 2005
    Assignee: Balluff GmbH
    Inventors: Martin Kurz, Gerd Eckel, Roland Holder, Hansjuergen Eberle, Roland Springer, Michael Hoffmann, Walter Roth
  • Publication number: 20050060028
    Abstract: The invention relates to stents with at least one hemocompatible coating which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.
    Type: Application
    Filed: October 15, 2002
    Publication date: March 17, 2005
    Inventors: Roland Horres, Michael Hoffmann, Erika Hoffman, Donato Di Biase, Volker Faust
  • Publication number: 20050037132
    Abstract: The invention relates to anti-thrombogenic surfaces and a process for making said surfaces. The process is primarily used for the anti-thrombogenic coating of hydrophobic surfaces of medical products coming into direct contact with blood and coagulable blood products.
    Type: Application
    Filed: April 24, 2003
    Publication date: February 17, 2005
    Inventors: Roland Horres, Michael Hoffmann, Sabine Kuesters, Marita Linssen
  • Publication number: 20040235667
    Abstract: Pyrazolyl-substituted thienyloxypyridines of the formula I 1
    Type: Application
    Filed: February 24, 2004
    Publication date: November 25, 2004
    Inventors: Michael Hoffmann, Liliana Parra Rapado, Wolfgang von Deyn, Ernst Baumann, Markus Kordes, Ulf Misslitz, Matthias Witschel, Cyrill Zagar, Andreas Landes
  • Publication number: 20040234575
    Abstract: The invention relates to the use of polysaccharides, that comprise the sugar building unit N-acylglucosamine, for the preparation of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with these polysaccharides, which are classified to be the common biosynthetic precursor substances of heparin and heparansulphates. Described are medical devices coated according to invention, especially stents, which comprise paclitaxel as antiproliferative active agent as well as the use of these stents for the prevention of restenosis.
    Type: Application
    Filed: May 24, 2004
    Publication date: November 25, 2004
    Inventors: Roland Horres, Marita Katarina Linssen, Michael Hoffmann, Erika Hoffmann, Donato Di Biase, Volker Faust
  • Patent number: 6806819
    Abstract: An integrated circuit for generating targeted bitlength manipulation of a transmitter for output of a serial datastream. A control unit (5) provides instructions regarding respective partial bits in a form of a partial bit vector (7) depending on bit statuses to be sent, and determines bitlengths for the serial datastream for output (9) to a wire or a signaling converter. The datastream (9) is generated using two partial bit register chains (14a-d, 15a-d), whose serial outputs (16, 17) are connected using a joining gate.
    Type: Grant
    Filed: February 24, 2003
    Date of Patent: October 19, 2004
    Assignee: Phoenix Contact GmbH & Co. KG
    Inventor: Michael Hoffmann
  • Publication number: 20040202783
    Abstract: An adsorbent for whole blood in the form of essentially spherical non-aggregated particles. The adsorbent comprises a porous carrier material having an average pore size of ≦1.5 &mgr;m, whereby a maximum of 50% of the pore volume may be in pores having a pore size of >1.5 &mgr;m, whereby the outer surfaces of the porous carrier material have at least one surface modification M1 so that the outer surface essentially does not interact with blood cells, and the inner surfaces of the porous carrier material, e.g., the surfaces of the pores of the porous carrier material, have at least one surface modification M2 which interacts with substances present in blood.
    Type: Application
    Filed: September 12, 2003
    Publication date: October 14, 2004
    Inventors: Hanno Baumann, Franz-Josef Gerner, Michael Hoffmann, Roland Horres, Andreas Kokott, Hans-Peter Leinenbach, Gunther Mathar, Wolfgang Metzger, Veit Otto, Walter Ruger, Martin Schimmel
  • Publication number: 20040198609
    Abstract: 4-Alkyl-substituted thienyloxypyridines of the formula I 1
    Type: Application
    Filed: February 24, 2004
    Publication date: October 7, 2004
    Inventors: Michael Hoffmann, Liliana Parra Rapado, Wolfgang von Deyn, Ernst Baumann, Markus Kordes, Ulf Misslitz, Matthias Witschel, Cyrill Zagar, Andreas Landes
  • Patent number: 6764771
    Abstract: The invention relates to a product (1), particularly a gas turbine blade that can be exposed to a hot aggressive gas (7). The product (1) has a metallic basic body (2), which is provided with a thermal barrier coating (4) having a spinel of the composition AB2O4.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: July 20, 2004
    Assignee: Siemens Aktiengesellschaft
    Inventors: Beate Heimberg, Wolfram Beele, Karl Kempter, Ulrich Bast, Thomas Haubold, Michael Hoffmann, Axel Endriss, Peter Greil, Chu-Wan Hong, Fritz Aldinger, Hans J. Seifert
  • Publication number: 20040112042
    Abstract: The invention relates to a method for desulfating a nitrogen oxide storage catalyst that contains stored nitrogen oxides and sulfur oxides and that forms part of an exhaust gas purification system of a lean-burn engine. The method provides that, to initiate desulfation, the temperature of the catalyst is increased to the point where thermal desorption of the nitrogen oxides stored in the catalyst sets in, and the onset of thermal desorption of the nitrogen oxides is used as the signal to enrich the air/fuel mixture to perform the desulfation.
    Type: Application
    Filed: August 8, 2003
    Publication date: June 17, 2004
    Applicant: OMG AG & CO. KG
    Inventors: Michael Hoffmann, Harald Klein, Klaus-Ingo Prieger, Thomas Kreuzer
  • Patent number: 6748917
    Abstract: In internal combustion engines having direct injection, an injector injects fuel into the combustion chamber to form an ignitable fuel/air mixture with combustion air supplied separately, the mixture being ignitable by a spark plug. The fuel is injected in a conical pattern, and the electrodes are protected from wetting by fuel and from coking if they are located outside the lateral surface of the fuel cone produced by the injection nozzle. To introduce an ignitable mixture between the electrodes and to ensure optimum operating performance of the internal combustion engine by improving the combustion process, a combustion chamber is configured so that the fuel cone is injected in a free jet which is substantially completely unaffected by the combustion chamber perimeter, and the electrodes of the spark plug project into a fuel vortex emerging from the lateral surface during injection.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: June 15, 2004
    Assignee: DaimlerChrysler AG
    Inventors: Michael Hoffmann, Uwe Kreckel
  • Publication number: 20040065078
    Abstract: The invention provides a process for reducing the amounts of carbon monoxide, hydrocarbons and soot particles in the lean exhaust gas from an internal combustion engine using a particle filter, wherein the soot particles have a soot ignition temperature TZ and the particle filter is regenerated from time to time by raising the temperature of the particle filter to above the soot ignition temperature and burning the soot particles, wherein the temperature of the filter is increased to the temperature required to initiate soot ignition by burning additional fuel on the catalytic coating when the exhaust gas back pressure reaches a predetermined value. The process is characterised in that the particle filter is provided with a catalytic coating comprising a first group of components for reducing the ignition temperature of soot, said first group of components contains at least one oxygen storage component and at least one platinum group metal selected from the group consisting of platinum, palladium and rhodium.
    Type: Application
    Filed: November 14, 2003
    Publication date: April 8, 2004
    Inventors: Adolf Schafer-Sindlinger, Marcus Pfeifer, Ulrich Hackbarth, Wilfried Muller, Egbert Lox, Thomas Kreuzer, Roger Staab, Michael Hoffmann, Jurgen Gieshoff
  • Publication number: 20040009591
    Abstract: The present invention relates to in vitro cultured skin tissue, and in particular to cultured skin tissue comprising exogenous genes encoding angiogenic growth factors. In some embodiments, the keratinocytes express exogenous angiopoietin-1 or a member of the VEGF family, preferably VEGF-A. In particularly preferred embodiments, the keratinocytes are incorporated into cultured skin tissue.
    Type: Application
    Filed: April 29, 2003
    Publication date: January 15, 2004
    Applicant: Stratatech Corporation
    Inventors: Allen Comer, Michael Hoffmann, Lynn-Allen Hoffmann
  • Publication number: 20030232207
    Abstract: Two-layered or three-layered polymer tubing for use as a pressurized fluid conduit in automobiles can be either walled or have walls continuously or partially corrugated. The tubing has an outer layer of a hard polymer molding material and an inner layer of a soft rubber-like polymer or a polymer mixture. The inner layer can be provided on the innerside with a layer of a thermoplastic adhesion-modified elastomer composition. The a materials are selected for the layers to provide a so-called “hard-soft-combination”. The rubber-like polymer composition has a hardness in the range of 30 Shore A to 60 Shore D, especially of about 30 Shore A to 90 Shore A, the compositions being selected so that they are processable by coextrusion or the so-called conex method and adhere directly to each other non-positively or positively fitted, i. e. without additional bonding agent, without delaminating.
    Type: Application
    Filed: May 7, 2003
    Publication date: December 18, 2003
    Applicant: EMS-CHEMIE AG
    Inventors: Helmut Thullen, Georg Stoeppelmann, Ralph Kettl, Michael Hoffmann
  • Patent number: 6655046
    Abstract: A device and a process for drying thin layers or films which are manufactured by applying a coating mass, which is produced on an aqueous basis, to a support, the said layer or film being transported through a drying device having at least one drying zone, is characterized in that in at least one drying zone, designated as moisture-compensation zone, air is supplied which has a moisture content corresponding to the constant moisture content of the film to be prepared or the layer to be prepared.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: December 2, 2003
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Wolfgang Schäfer, Peter Schwarz, Rudi Brathuhn, Michael Hoffmann
  • Publication number: 20030190444
    Abstract: The invention relates to a hydraulic line for motor vehicles based on thermoplastic polymers comprising at least one layer comprising a molding compound based on polyamide, wherein the polyamide molding compound contains nano-scale fillers in a quantity of 0.5 to 50% by weight, in particular in a quantity of 1 to 30% by weight per 100 parts by weight of the polymer matrix.
    Type: Application
    Filed: February 3, 2003
    Publication date: October 9, 2003
    Inventors: Georg Stoppelmann, Michael Hoffmann
  • Publication number: 20030172199
    Abstract: An integrated circuit for generating targeted bitlength manipulation of a transmitter for output of a serial datastream is disclosed, wherein a control unit (5) provides instructions regarding the respective partial bits in the form of a partial bit vector (7) depending on bit statuses to be sent, and determines the bitlengths for the serial datastream for output (9) to the wire or a signaling converter. A datastream (9) is generated using two partial bit register chains (14a-d, 15a-d), whose serial outputs (16, 17) are connected using a joining gate.
    Type: Application
    Filed: February 24, 2003
    Publication date: September 11, 2003
    Inventor: Michael Hoffmann