Patents by Inventor Michael A Horning

Michael A Horning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230226187
    Abstract: The present invention relates to nutritional formulations for increasing sports and other physical performance and that have beneficial effects on health and wellness for various populations. The invention includes molecular compounds as disclosed. A preferred embodiment is a molecule type based on a glycerol backbone, with three glycerol functional groups B1, B2, B3, wherein one or more of the B groups may correspond to one of the functional energy groups A1, A2 or A3, as disclosed. The invention includes nutritional formulations, some based on the inventive molecular compounds. The invention also includes method of using, administering, and implementing the above, including computer implemented and computer assisted methods.
    Type: Application
    Filed: January 13, 2023
    Publication date: July 20, 2023
    Applicant: Today Inc.
    Inventors: George A. Brooks, Michael A. Horning, Iñigo San Millán
  • Patent number: 11202464
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis, which is the % of glucose production that comes from gluconeogenesis (“GNG”), as opposed to glycogenolysis (“GLY”), the other form of glucose production. Nutritional formulations, materials, cocktails and methods for feeding patients by parenteral and other means are disclosed. The amount, type and rate of such nutritional feeding are typically based upon the above estimating. The invention discloses formulations that contain labels, such as deuterium, for medical diagnostics, such as for estimating BES and fractional gluconeogenesis.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: December 21, 2021
    Assignee: Run Them Sweet LLC
    Inventors: Michael A. Horning, George A. Brooks
  • Publication number: 20210335486
    Abstract: A system and method for controlling a computerized device's display to provide a compact and informative graphical user interface providing historical data-based forecasting for clinical trial-related activities. The graphical user interface performs guided prompting for development of clinical trial plans on a per-study basis, historical data-based budgeting on a per-country basis, and budget negotiation on a per-supplier basis, to effectively form clinical trial agreements. Further, the system provides a high degree of flexibility and feedback to the user during these activities, including via graphical user interfaces providing mechanisms for accessing historical payment data and/or fair market value data derived therefrom, to allow for comparison and/or selection of countries/suppliers to be used in clinical trials and/or to negotiate clinical trial budgets based on actual historical payment data.
    Type: Application
    Filed: April 28, 2021
    Publication date: October 28, 2021
    Inventors: Kyle Russell Cunningham, Ryan Patrick Kelly, Todd Michael Horning, Catherine Alyssa Click
  • Publication number: 20210265049
    Abstract: A system and method for controlling a computerized device's display to provide a graphical user interface that renders compact and informative graphical user interface images while also providing for flexible and accurate administration of clinical trial-related activities, namely, flexible allocation of payments in accordance with an applicable clinical trial agreement. Further, the system provides a graphical user interface providing tracking and feedback to the user during the payment allocation process to avoid allocation errors. More particularly, the graphical user interface provides guided prompting for allocation to approved/relevant persons, in accordance with clinical trial agreements, while providing a high degree of flexibility for specifying an allocations, and while displaying various visual elements providing feedback to ensure that allocations are made with internal consistency, to reduce and/or avoid human or other errors.
    Type: Application
    Filed: February 25, 2021
    Publication date: August 26, 2021
    Inventors: Kyle Russell Cunningham, Ryan Patrick Kelly, Todd Michael Horning
  • Publication number: 20210127728
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Application
    Filed: December 21, 2020
    Publication date: May 6, 2021
    Inventors: George A. Brooks, Michael A. Horning
  • Publication number: 20210106039
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Application
    Filed: December 22, 2020
    Publication date: April 15, 2021
    Inventors: George A. Brooks, Michael A. Horning
  • Patent number: 10905148
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Grant
    Filed: December 22, 2018
    Date of Patent: February 2, 2021
    Assignee: Run Them Sweet LLC
    Inventors: George A. Brooks, Michael A. Horning
  • Patent number: 10897924
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Grant
    Filed: August 26, 2018
    Date of Patent: January 26, 2021
    Assignee: Run Them Sweet LLC
    Inventors: George A. Brooks, Michael A. Horning
  • Publication number: 20200158714
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Application
    Filed: January 11, 2020
    Publication date: May 21, 2020
    Inventors: George A. Brooks, Michael A. Horning
  • Patent number: 10571459
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: February 25, 2020
    Assignee: RUN THEM SWEET, LLC
    Inventors: Michael A. Horning, George A. Brooks
  • Publication number: 20190150496
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Application
    Filed: December 22, 2018
    Publication date: May 23, 2019
    Applicant: Run Them Sweet LLC
    Inventors: George A. Brooks, Michael A. Horning
  • Patent number: 10206422
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: February 19, 2019
    Assignee: Run Them Sweet LLC
    Inventors: Michael A. Horning, George A. Brooks
  • Publication number: 20190050781
    Abstract: A computer-implemented evaluation method for evaluating an employee includes providing an evaluation dashboard application to participants capable of generating a collective progress report indicating a proportion of group members who have transmitted external-evaluation information at a time the collective progress report is generated, and further capable of generating a plurality of individual progress reports respectively indicating a completeness of external-evaluation information received from each of the plurality of group members at a time the plurality of individual progress reports are generated. The collective progress report and the plurality of individual progress reports are accessible by each participant executing the evaluation dashboard application on a remote computer without communicating with another participant. A participant in the evaluation process can anonymously check on the progress of other participants in the evaluation process in real time.
    Type: Application
    Filed: August 11, 2017
    Publication date: February 14, 2019
    Inventors: Michael HORNING, JR., James HOYER, David QUINN-JACOBS
  • Publication number: 20180360094
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Application
    Filed: August 26, 2018
    Publication date: December 20, 2018
    Applicant: Run Them Sweet LLC
    Inventors: George A. Brooks, Michael A. Horning
  • Patent number: 10139393
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: November 27, 2018
    Assignee: RUN THEM SWEET LLC
    Inventors: Michael A. Horning, George A. Brooks
  • Patent number: 10088470
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: October 2, 2018
    Assignee: Run Them Sweet, LLC
    Inventors: Michael A. Horning, George A. Brooks
  • Patent number: 10085476
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: October 2, 2018
    Assignee: Run Them Sweet, LLC
    Inventors: Michael A. Horning, George A. Brooks
  • Patent number: 10010104
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: July 3, 2018
    Assignee: Run Them Sweet, LLC
    Inventors: Michael A. Horning, George A. Brooks
  • Patent number: 9980508
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: May 29, 2018
    Assignee: Run Them Sweet, LLC
    Inventors: Michael A. Horning, George A. Brooks
  • Publication number: 20180139999
    Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
    Type: Application
    Filed: November 3, 2017
    Publication date: May 24, 2018
    Applicant: Run Them Sweet LLC
    Inventors: Michael A. Horning, George A. Brooks