Abstract: Provided herein are therapeutic agents having specificity for human CLPTM1L/CRR9 polypeptide, including therapeutic agents comprising one or more CLPTM1L-targeting agents, compositions comprising such therapeutic agents, and methods of using such compositions for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L/CRR9 protein dysfunction (e.g., pathogenic production, modification, or function). In particular, provided herein are fully human monoclonal antibodies against human CLPTM1L/CRR9 protein and methods of using such antibodies for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L/CRR9 protein dysfunction (e.g., pathogenic production, modification, or function).

Abstract: Provided herein are therapeutic agents having specificity for human CLPTM1L/CRR9 polypeptide, including therapeutic agents comprising one or more CLPTM1L-targeting agents, compositions comprising such therapeutic agents, and methods of using such compositions for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L/CRR9 protein dysfunction (e.g., pathogenic production, modification, or function). In particular, provided herein are fully human monoclonal antibodies against human CLPTM1L/CRR9 protein and methods of using such antibodies for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L/CRR9 protein dysfunction (e.g., pathogenic production, modification, or function).

Abstract: Apparatuses, methods, and computer program products for quilting webs without compressing the webs. A quilting machine includes a needle bar to which needles are attached, needle thread passing through each needle, a looper shaft to which loopers are attached, a looper corresponding to each needle and from which looper thread is provided to form stitches, and a retainer bar to which spreaders are attached to facilitate stitching. A drive pulley powered by a first servo motor rotates cranks to move the needles through a cycle and rotates a belt which rotates an indexer pulley. Rotation of the indexer pulley oscillates the looper shaft and reciprocates the retainer bar. Another drive pulley powered by a second servo motor operates to move an input web through the machine between chain stiches.

Abstract: A method and a system for performing real-time, continuous, measurements of the boron concentration in the water entering a nuclear reactor coolant system. The invention utilizes knowledge of the impact that boron contained in liquid water has on the attenuation of acoustic or ultrasonic waves. This information, coupled with radiation damage resistant and high temperature operability capable transmitter and receiver equipment, provides the means to place the measurement system sensors and signal processing electronics on the reactor coolant system charging flow piping or the hot leg or cold leg of the reactor coolant loop. This will allow the reactor operator to directly monitor both the reactor coolant system boron concentration value and detect changes in the reactor coolant system boron concentration relative to a reference value as they occur.

Abstract: Apparatuses, methods, and computer program products for quilting webs without compressing the webs. A quilting machine includes a needle bar to which needles are attached, needle thread passing through each needle, a looper shaft to which loopers are attached, a looper corresponding to each needle and from which looper thread is provided to form stitches, and a retainer bar to which spreaders are attached to facilitate stitching. A drive pulley powered by a first servo motor rotates cranks to move the needles through a cycle and rotates a belt which rotates an indexer pulley. Rotation of the indexer pulley oscillates the looper shaft and reciprocates the retainer bar. Another drive pulley powered by a second servo motor operates to move an input web through the machine between chain stiches.

Abstract: Provided herein are therapeutic agents having specificity for human CLPTM1L/CRR9 polypeptide, including therapeutic agents comprising one or more CLPTM1L-targeting agents, compositions comprising such therapeutic agents, and methods of using such compositions for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L/CRR9 protein dysfunction (e.g., pathogenic production, modification, or function). In particular, provided herein are fully human monoclonal antibodies against human CLPTM1L/CRR9 protein and methods of using such antibodies for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L/CRR9 protein dysfunction (e.g., pathogenic production, modification, or function).

Abstract: A system that measures the temperature distribution of the reactor coolant flowing through the hot leg or cold leg pipes by measuring the speed of sound time delay. This concept uses radiation hardened and temperature tolerant ultrasonic signal drivers based on vacuum micro-electronic technology. The system employs ultrasonic signals propagated through water, and relies on the characteristic that the speed of sound changes as the density and temperature of the water changes. Thus, a measured difference in the speed of sound in water may be directly correlated to a temperature change of the water.

Abstract: Provided herein are therapeutic agents having specificity for human CLPTM1L polypeptide, including therapeutic agents comprising one or more CLPTM1L-targeting agents, compositions comprising such therapeutic agents, and methods of using such compositions for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L protein dysfunction (e.g., pathogenic production, modification, or function).

Abstract: Apparatuses, methods, and computer program products for quilting webs. A quilting machine includes a cutting edge, a looper from which thread is provided to form stitches, and an adjuster assembly. The adjuster assembly extends an adjuster toward the thread between the looper and the retainer. When the adjuster is moved, a predetermined amount of thread is pulled away from the looper by the adjuster to provide a controlled length of thread between the looper and the cutting edge. The looper assembly may also include an air nozzle that urges the thread away from the adjuster after the thread has been cut. The thread passes through a thread tension monitor that monitors tension in the thread. The tension monitor includes a lift arm that selectively disables the tension monitor so that a loss of tension in the sewing head does not shut down the quilting machine.

Abstract: Apparatus for amplifying low level signals within a nuclear plant's containment building, derived from the ex-core nuclear instrumentation system. The system employs vacuum micro-electronic devices in place of conventional pre-amplifier assemblies to position the pre-amplifier assemblies closer to and within the vicinity of the ex-core detector outputs.

Abstract: Provided herein are therapeutic agents having specificity for human CLPTM1L polypeptide, including therapeutic agents comprising one or more CLPTM1L-targeting agents, compositions comprising such therapeutic agents, and methods of using such compositions for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L protein dysfunction (e.g., pathogenic production, modification, or function).

Abstract: Provided herein are therapeutic agents having specificity for human CLPTM1 L polypeptide, including therapeutic agents comprising one or more CLPTM1 L-targeting agents, compositions comprising such therapeutic agents, and methods of using such compositions for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1 L protein dysfunction (e.g., pathogenic production, modification, or function).

Abstract: Apparatuses, methods, and computer program products for quilting webs. A quilting machine includes a cutting edge, a looper from which thread is provided to form stitches, and an adjuster assembly that includes a plurality of selectable positions. The adjuster assembly extends an adjuster toward the thread between the looper and the retainer. When the adjuster is moved, a predetermined amount of thread is pulled away from the looper by the adjuster to provide a controlled length of thread between the looper and the cutting edge. The adjuster is configured to be moved to an intermediate selectable position prior to starting a quilting pattern, and from the intermediate position to another selectable position subsequent to starting the quilting pattern.

Abstract: Apparatuses, methods, and computer program products for quilting webs. A quilting machine includes a cutting edge, a looper from which thread is provided to form stitches, and an adjuster assembly that includes a plurality of selectable positions. The adjuster assembly extends an adjuster toward the thread between the looper and the retainer. When the adjuster is moved, a predetermined amount of thread is pulled away from the looper by the adjuster to provide a controlled length of thread between the looper and the cutting edge. The adjuster is configured to be moved to an intermediate selectable position prior to starting a quilting pattern, and from the intermediate position to another selectable position subsequent to starting the quilting pattern.

Abstract: Apparatuses, methods, and computer program products for quilting webs. A quilting machine includes a cutting edge, a looper from which thread is provided to form stitches, and an adjuster assembly. The adjuster assembly extends an adjuster toward the thread between the looper and the retainer. When the adjuster is moved, a predetermined amount of thread is pulled away from the looper by the adjuster to provide a controlled length of thread between the looper and the cutting edge. The looper assembly may also include an air nozzle that urges the thread away from the adjuster after the thread has been cut. The thread passes through a thread tension monitor that monitors tension in the thread. The tension monitor includes a lift arm that selectively disables the tension monitor so that a loss of tension in the sewing head does not shut down the quilting machine.

Abstract: A pulsed sonar-based wireless rod position indication system that utilizes nuclear radiation and high temperature tolerant hardware. The pulsed sonar-based rod position indication system can precisely locate the rod position by measuring the time of flight of a transmitted signal and by using the phase and amplitude information of the same transmitted signal. Primary and secondary antenna probes located in the interior of the control rod drive rod travel housing and full hardware redundancy provide for improved accuracy. The time of flight, phase and amplitude raw signals are inputted to a wireless data transmitter capable of sending the raw signals to a receiver antenna located elsewhere inside a containment for further processing.

Abstract: A method and a system for performing real-time, continuous, measurements of the boron concentration in the water entering a nuclear reactor coolant system. The invention utilizes knowledge of the impact that boron contained in liquid water has on the attenuation of acoustic or ultrasonic waves. This information, coupled with radiation damage resistant and high temperature operability capable transmitter and receiver equipment, provides the means to place the measurement system sensors and signal processing electronics on the reactor coolant system charging flow piping or the hot leg or cold leg of the reactor coolant loop. This will allow the reactor operator to directly monitor both the reactor coolant system boron concentration value and detect changes in the reactor coolant system boron concentration relative to a reference value as they occur.

Abstract: A system that measures the temperature distribution of the reactor coolant flowing through the hot leg or cold leg pipes by measuring the speed of sound time delay. This concept uses radiation hardened and temperature tolerant ultrasonic signal drivers based on vacuum micro-electronic technology. The system employs ultrasonic signals propagated through water, and relies on the characteristic that the speed of sound changes as the density and temperature of the water changes. Thus, a measured difference in the speed of sound in water may be directly correlated to a temperature change of the water.

Abstract: A pulsed sonar-based wireless rod position indication system that utilizes nuclear radiation and high temperature tolerant hardware. The pulsed sonar-based rod position indication system can precisely locate the rod position by measuring the time of flight of a transmitted signal and by using the phase and amplitude information of the same transmitted signal. Primary and secondary antenna probes located in the interior of the control rod drive rod travel housing and full hardware redundancy provide for improved accuracy. The time of flight, phase and amplitude raw signals are inputted to a wireless data transmitter capable of sending the raw signals to a receiver antenna located elsewhere inside a containment for further processing.

Abstract: Apparatus for amplifying low level signals within a nuclear plant's containment building, derived from the ex-core nuclear instrumentation system. The system employs vacuum micro-electronic devices in place of conventional pre-amplifier assemblies to position the pre-amplifier assemblies closer to and within the vicinity of the ex-core detector outputs.