Abstract: A hybrid modular storage fetching system is described. In an example implementation, the system may include a warehouse execution system adapted to generate a picking schedule for picking pick-to-cart and high-density storage items, and an AGV dispatching system adapted to dispatch a cart automated guided vehicle and a modular storage fetching automated guided vehicle based on the picking schedule. The cart automated guided vehicle may be adapted autonomously transport a carton through a pick-to-cart area and to a pick-cell station. The modular storage fetching automated guided vehicle may be adapted to synchronously autonomously transport a modular storage unit containing items to be placed in the cartons from a high-density storage area to the pick-cell station.

Abstract: A fining package for a glass composition may include a sulfate or a sulfide in an amount from about 0.001 to about 1 mol % of the glass composition. The fining package may include a multivalent compound, such as CeO2, SnO2, or Fe2O3, in an amount from about 0.001 to about 1 mol % of the glass composition. The fining package may be sulfide-free. The fining package may be free from a reducing agent for reducing sulfate to sulfide. The fining package may be free of at least one of Cl, F, Sn, Ce, and As. The glass composition may be used to form glass tubing. The glass tubing may be used to form a pharmaceutical packaging.

Abstract: Methods, systems, and computer-readable media that manage cloud computing environments. A pool manager creates a pool of cloud computing environments according to a pool specification specifying a headroom threshold of the pool. The pool manager receives, from a requester computer, a request to claim a cloud computing environment. The pool manager determines that one or more cloud computing environments are available. In response, the pool manager provides to the requesting computer credentials for accessing the cloud computing environment. The pool manager designates the cloud computing environment as claimed and unavailable to other requester computers until receiving a notification indicating that the cloud computing environment is unclaimed. The pool manager ensures that the correct number of environments are available on a pre-determined schedule.

Abstract: Methods, systems, and computer-readable media that manage cloud computing environments. A pool manager creates a pool of cloud computing environments according to a pool specification specifying a headroom threshold of the pool. The pool manager receives, from a requester computer, a request to claim a cloud computing environment. The pool manager determines that one or more cloud computing environments are available. In response, the pool manager provides to the requesting computer credentials for accessing the cloud computing environment. The pool manager designates the cloud computing environment as claimed and unavailable to other requester computers until receiving a notification indicating that the cloud computing environment is unclaimed. The pool manager ensures that the correct number of environments are available on a pre-determined schedule.

Abstract: A fillable base for a portable light stand, the base including: a hollow structure made from moulded plastics material, the hollow structure having an upper portion and a lower portion with a generally circular footprint. The lower portion of the hollow structure has a substantially vertical cylindrical outer side wall, and the upper portion of the hollow structure has a conical outer side wall. The conical outer side wall has an outer edge extending from a top edge of the cylindrical side wall to an apex of the upper portion of the structure. The structure also has a recess that opens at the apex and within which one end of an elongate pole can be received.

Abstract: A fillable base for a portable light stand, the base including: a hollow structure made from moulded plastics material, the hollow structure having an upper portion and a lower portion with a generally circular footprint. The lower portion of the hollow structure has a substantially vertical cylindrical outer side wall, and the upper portion of the hollow structure has a conical outer side wall. The conical outer side wall has an outer edge extending from a top edge of the cylindrical side wall to an apex of the upper portion of the structure. The structure also has a recess that opens at the apex and within which one end of an elongate pole can be received.

Abstract: Particular aspects provide for use of the ?-herpesvirus Cytomegalovirus (CMV: e.g., RhCMV and HCMV) as a uniquely evolved “vector” for safely initiating and indefinitely maintaining high level cellular and humoral immune responses (against, e.g., HIV, SIV, TB, etc.). Particular aspects provide a method for treatment or prevention of, e.g., HIV, SIV or TB, comprising infection of a subject in need thereof with at least one recombinant CMV-based vector (e.g., HCMV or RhCMV) comprising an expressible HIV/SIV/TB antigen or a variant or fusion protein thereof. In particular embodiments of the method, infection is of an to immunocompetent, HCMV or RhCMV seropositive subject. Additional aspects provide for RhCMV- and HCMV-based vaccine vectors, and versions thereof with suicide or safety means. Further aspects provide pharmaceutical compositions comprising the inventive CMV-based vaccine vectors.

Abstract: A method for the regulated removal of heterologous genetic material from disseminating viral vaccine vectors is provided.

Abstract: A fillable base for a portable light stand, the base including: a hollow structure made from moulded plastics material, the hollow structure having an upper portion and a lower portion with a generally circular footprint. The lower portion of the hollow structure has a substantially vertical cylindrical outer side wall, and the upper portion of the hollow structure has a conical outer side wall. The conical outer side wall has an outer edge extending from a top edge of the cylindrical side wall to an apex of the upper portion of the structure. The structure also has a recess that opens at the apex and within which one end of an elongate pole can be received.

Abstract: The present disclosure relates to recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors encoding heterologous antigens, such as pathogen-specific antigens or tumor antigens, which may be used, for example, for the treatment or prevention of infectious disease or cancer. The recombinant RhCMV or HCMV vectors elicit and maintain high level cellular immune responses specific for the heterologous antigen while including deletions in one or more genes essential or augmenting for CMV replication, dissemination or spread.

Abstract: Particular aspects provide for use of the ?-herpesvirus Cytomegalovirus (CMV: e.g., RhCMV and HCMV) as a uniquely evolved “vector” for safely initiating and indefinitely maintaining high level cellular and humoral immune responses (against, e.g., HIV, SIV, TB, etc.). Particular aspects provide a method for treatment or prevention of, e.g., HIV, SIV or TB, comprising infection of a subject in need thereof with at least one recombinant CMV-based vector (e.g., HCMV or RhCMV) comprising an expressible HIV/SIV/TB antigen or a variant or fusion protein thereof. In particular embodiments of the method, infection is of an immunocompetent, HCMV or RhCMV seropositive subject. Additional aspects provide for RhCMV- and HCMV-based vaccine vectors, and versions thereof with suicide or safety means. Further aspects provide pharmaceutical compositions comprising the inventive CMV-based vaccine vectors.

Abstract: A method for forming a structure includes providing a glass or glass ceramic tubular structure (110) having an interior (150) and exterior surface (160) and at least a partially closed end region (140); heating the glass or glass ceramic tubular structure (110) to at least its softening point by: providing a laser beam; directing the laser beam (130) down the interior surface of the glass or glass ceramic tubular structure (110), at least some of the laser beam (130) directed at an angle greater than a predetermined incidence angle; and the laser beam (130) impinging on the closed end region (140) where at least some of the laser beam (130) is absorbed by the closed end region (140) of the glass or glass ceramic tubular structure; and moving at least one of: the glass or glass ceramic tubular structure or the end region relative to each other to form at least a two-dimensional shape from the glass or glass ceramic tubular structure.

Abstract: A method of printing a 3D object includes feeding one or more preformed materials from a feed outlet into a build zone in which a hot spot is located and using the hot spot to selectively heat the one or more preformed materials to a viscous state. Object layers are formed by depositing portions of the preformed materials on a build surface, or on another object layer on the build surface, while effecting relative motion between the build surface and the feed outlet.

Abstract: There is provided a non-PCR based method for construction of a DNA recombination fragment with necessary flanking regions homologous to a desired site of genetic manipulation within a target DNA required for recombination-based manipulation of said target DNA, comprising the steps of: A) identifying a desired site of insertion for a genetic element in said target DNA; B) locating an endogenous, native, half-site of a selected restriction endonuclease present upstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 5? extent of an upstream homology region; C) locating an endogenous, native, half-site of the same selected restriction endonuclease present downstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 3? extent of a downstream homology region; D) synthesising a flanking region cassette resulting in juxtapositioning of the upstream and downstream half-sites thereby causing formation of complete restriction site for

Abstract: A tool for removing a runner from an agricultural bin having a lever arm and a plurality of crossbars. The lever arm may be directly, or indirectly, engaged with a rotatable crossbar which may have a plurality of protrusions for engaging corresponding tabs of a runner. To use the tool, a user may align the protrusions of the rotatable crossbar with the corresponding tabs of a runner engaged within a leg of an agricultural bin, then the user may press down on the lever arm, causing the crossbar to rotate and engage the tabs. As the user continues to press down on the lever arm, the tabs eventually disengage from corresponding openings in the leg of the agricultural bin, allowing the user to remove the runner from the bin.

Abstract: The present disclosure relates to recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors encoding heterologous antigens, such as pathogen-specific antigens or tumor antigens, which may be used, for example, for the treatment or prevention of infectious disease or cancer. The recombinant RhCMV or HCMV vectors elicit and maintain high level cellular immune responses specific for the heterologous antigen while including deletions in one or more genes essential or augmenting for CMV replication, dissemination or spread.

Abstract: Systems and methods are provided for enabling or disabling a DMS device during an IDA method. Each cycle of the method includes a survey scan step, producing a precursor ion mass spectrum, and an MS/MS scan step. During the MS/MS scan step, one or more user-defined MS/MS scans are performed that correspond to compounds of interest found in the precursor ion mass spectrum. With each user-defined MS/MS scan, a DMS enable parameter that determines if the DMS device is enabled or disabled and one or more DMS parameters necessary to enable the DMS device for the corresponding compound of interest are received. During the MS/MS scan step, for each user-defined MS/MS scan, the DMS device is enabled or disabled according to the DMS enable parameter and one or more parameters of the DMS device are set according to the one or more DMS parameters.

Abstract: Disclosed herein are methods and apparatuses for adding thermal energy to a glass melt. Apparatuses for generating a thermal plasma disclosed herein comprise an electrode, a grounded electrode, a dielectric plasma confinement vessel extending between the two electrodes, and a magnetic field generator extending around the dielectric plasma confinement vessel. Also disclosed herein are methods for fining molten glass comprising generating a thermal plasma using the apparatuses disclosed herein and contacting the molten glass with the thermal plasma. Glass structures produced according to these methods are also disclosed herein.

Abstract: Systems and methods are provided for enabling or disabling a DMS device during an IDA method. Each cycle of the method includes a survey scan step, producing a precursor ion mass spectrum, and an MS/MS scan step. During the MS/MS scan step, one or more user-defined MS/MS scans are performed that correspond to compounds of interest found in the precursor ion mass spectrum. With each user-defined MS/MS scan, a DMS enable parameter that determines if the DMS device is enabled or disabled and one or more DMS parameters necessary to enable the DMS device for the corresponding compound of interest are received. During the MS/MS scan step, for each user-defined MS/MS scan, the DMS device is enabled or disabled according to the DMS enable parameter and one or more parameters of the DMS device are set according to the one or more DMS parameters.

Abstract: There is provided a non-PCR based method for construction of a DNA recombination fragment with necessary flanking regions homologous to a desired site of genetic manipulation within a target DNA required for recombination-based manipulation of said target DNA, comprising the steps of: A) identifying a desired site of insertion for a genetic element in said target DNA; B) locating an endogenous, native, half-site of a selected restriction endonuclease present upstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 5? extent of an upstream homology region; C) locating an endogenous, native, half-site of the same selected restriction endonuclease present downstream of the site within the DNA to be targeted for genetic manipulation and thereby defining the 3? extent of a downstream homology region; D) synthesising a flanking region cassette resulting in juxtapositioning of the upstream and downstream half-sites thereby causing formation of complete restriction site for