Patents by Inventor Michael A. Kapin

Michael A. Kapin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of disorders of the outer retina
    Patent number: 6509355
    Abstract: This invention is directed to the use of glutamate antagonists to treat the disorders of outer retina.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: January 21, 2003
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert J. Collier, Jr., Mark R. Hellberg, Michael A. Kapin, George E. Barnes, Michael L. Chandler
  • Use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina
    Publication number: 20020193373
    Abstract: The invention is directed to the use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina.
    Type: Application
    Filed: May 15, 2002
    Publication date: December 19, 2002
    Inventors: Robert J. Collier, Jr., Louis Desantis, Jr., Michael A. Kapin
  • Use of certain isoquinolinesulfonyl compounds for the treatment of glaucoma and ocular ischemia
    Patent number: 6403590
    Abstract: Isoquinolinesulfonyl compounds are used in ophthalmic compositions to treat glaucoma or other ischemic-borne ocular disorders such as retinopathies or optic neuropathies. These compounds vasodilate ocular blood vessels, lower IOP and prevent or reduce the progression of visual field loss.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: June 11, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, Michael A. Kapin, Louis M. Desantis, Jr.
  • Method of treating neurodegenerative disorders of the retina and optic nerve head
    Publication number: 20020049255
    Abstract: The use of 3-benzolphenylacetic acids and derivatives, including nepafenac, to treat neurodegenerative retinal disorders is disclosed.
    Type: Application
    Filed: August 13, 2001
    Publication date: April 25, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Daniel A. Gamache, Gustav Graff, John M. Yanni, Michael A. Kapin
  • Method of treating angiogenesis-related disorders
    Publication number: 20020037929
    Abstract: The use of 3-benzolphenylacetic acids and derivatives, including nepafenac, to treat angiogenesis-related disorders, including ophthalmic angiogenesis-related disorders such as diabetic retinopathy and exudative macular degeneration, is disclosed.
    Type: Application
    Filed: August 13, 2001
    Publication date: March 28, 2002
    Applicant: Alcon Universal Ltd.
    Inventors: Michael A. Kapin, David P. Bingaman, Daniel A. Gamache, Gustav Graff, John M. Yanni
  • Use of calpain inhibitors to treat ocular neural pathology
    Patent number: 6303579
    Abstract: The invention provides pharmaceutical compositions containing calpain inhibitors and methods of using these calpain inhibitors to prevent or ameliorate ocular neural tissue disease or damage.
    Type: Grant
    Filed: April 5, 1999
    Date of Patent: October 16, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Iok-Hou Pang, Michael A. Kapin, Louis DeSantis, Jr.
  • Use of certain isoquinolinesulfonyl compounds for the treatment of glaucoma and ocular ischemia
    Patent number: 6271224
    Abstract: The present invention relates to the field of ophthalmology. In particular the invention relates to the field of ocular disorders including visual field loss and glaucoma using an isoquinolinesulfonyl compound, which lowers intraocular pressure (IOP) and produces dilation of ocular blood vessels.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: August 7, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Michael A. Kapin, Louis M. Desantis, Jr.
  • Treatment of ischemic disorders of the retina and optic nerve head
    Patent number: 6020352
    Abstract: The use of polyamine site antagonists in treating ischemic disorders of the retina and optic nerve head are disclosed. Especially preferred are certain 1-phenyl-2-piperidinoalkanol derivatives, such as eliprodil and ifenprodil.
    Type: Grant
    Filed: November 18, 1997
    Date of Patent: February 1, 2000
    Assignee: Synthelabo
    Inventors: Michael A. Kapin, Louis Desantis, Jr., Bernard Scatton, Salomon Langer
  • Use of .omega.-conotoxin analogs for treating retinal and optic nerve head damage
    Patent number: 5965534
    Abstract: The invention is directed to the use of .omega.-conotoxins for the prevention and treatment of retinal or optic nerve head damage in humans. Compositions and methods are disclosed.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: October 12, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Iok-Hou Pang, Michael Kapin, Mark Hellberg
  • Treatment of retinal edema with brinzolamide
    Patent number: 5948801
    Abstract: Methods for preventing and treating retinal edema with brinzolamide are disclosed.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: September 7, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Rupa Doshi, Michael A. Kapin
  • Use of polyamine antagonists for the treatment of glaucoma
    Patent number: 5710165
    Abstract: Polyamine antagonists are found to be effective in preventing or reducing visual field loss associated with glaucoma. Especially preferred are certain 1-phenyl-2-piperidinoalkanol derivatives, such as eliprodil and ifenprodil.
    Type: Grant
    Filed: July 6, 1994
    Date of Patent: January 20, 1998
    Assignee: Synthelabo
    Inventors: Michael A. Kapin, Louis Desantis, Jr., Salomon Langer
  • Use of aliphatic carboxylic acid derivatives in ophthalmic disorders
    Patent number: 5681854
    Abstract: The use of certain aliphatic carboxylic acid derivatives to treat persons suffering from retinal or optic nerve head damage is disclosed.
    Type: Grant
    Filed: November 22, 1995
    Date of Patent: October 28, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Iok-Hou Pang, Michael A. Kapin
  • Intraocular irrigating solution containing a polyamine antagonist
    Patent number: 5604244
    Abstract: Pharmaceutical compositions useful in ophthalmic surgery are described. The compositions include one or more polyamine antagonists, and are useful for preventing or treating excitotoxicity associated with ophthalmic surgery. Methods of using the compositions in connection with ophthalmic surgical procedures are also described.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Michael A. Kapin