Abstract: A method of delivering a nebulized fluid for inhalation, including providing an aerosol generator, providing a container containing a fluid to be nebulized, providing a reservoir in fluid communication with the container and with the aerosol generator, providing a moveable member positioned to act upon the container in a manner to elect fluid therefrom, providing a linkage mechanism operable through a range of operating positions that is coupled to the moveable member to selectively control a distance of movement of the moveable member, selecting the distance of movement of the moveable member, moving the moveable member to eject fluid from the container into the reservoir, and operating the aerosol generator to elect fluid from the reservoir as a nebulized fluid for inhalation.

Abstract: A nebulizer comprising an aerosol generator and a titration mechanism comprising a dosing mechanism, a screw assembly, a plunger and an actuator, wherein the dosing mechanism is rotatably mounted in the nebulizer and the plunger is mounted in the nebulizer to travel along a longitudinal axis substantially perpendicular to the plane of rotation of the dosing mechanism. The actuator is mounted to the nebulizer to travel in the direction of the longitudinal axis. The screw mechanism allows the rotation of the dosing mechanism to fix a variable distance of travel of the plunger based on the selected dose, without moving the plunger longitudinally. This allows the user to verify and if necessary correct the selected dose prior to any drug being released from the vial. Operation of the actuator causes longitudinal movement, through the screw mechanism, to the plunger.

Abstract: A nebulizer comprising an aerosol generator and a titration mechanism comprising a dosing mechanism, a screw assembly, a plunger and an actuator, wherein the dosing mechanism is rotatably mounted in the nebulizer and the plunger is mounted in the nebulizer to travel along a longitudinal axis substantially perpendicular to the plane of rotation of the dosing mechanism. The actuator is mounted to the nebulizer to travel in the direction of the longitudinal axis. The screw mechanism allows the rotation of the dosing mechanism to fix a variable distance of travel of the plunger based on the selected dose, without moving the plunger longitudinally. This allows the user to verify and if necessary correct the selected dose prior to any drug being released from the vial. Operation of the actuator causes longitudinal movement, through the screw mechanism, to the plunger.

Abstract: An aerosolization device comprises a housing having a mouthpiece, an aerosol generator, a flow sensor and a controller. The controller is configured to begin operation of the aerosol generator upon receipt of a signal from the flow sensor indicating that a threshold flow rate has been achieved by a user when inhaling a tidal breath through the mouthpiece, and to stop operation after the passage of an operation time period that is selected such that continuation of the tidal breath delivers substantially all of the aerosol to the lungs.

Abstract: A nebulizer comprising an aerosol generator and a titration mechanism comprising a dosing mechanism, a screw assembly, a plunger and an actuator, wherein the dosing mechanism is rotatably mounted in the nebulizer and the plunger is mounted in the nebulizer to travel along a longitudinal axis substantially perpendicular to the plane of rotation of the dosing mechanism. The actuator is mounted to the nebulizer to travel in the direction of the longitudinal axis. The screw mechanism allows the rotation of the dosing mechanism to fix a variable distance of travel of the plunger based on the selected dose, without moving the plunger longitudinally. This allows the user to verify and if necessary correct the selected dose prior to any drug being released from the vial. Operation of the actuator causes longitudinal movement, through the screw mechanism, to the plunger.

Abstract: An aerosolization device comprises a housing having a mouthpiece, an aerosol generator, a flow sensor and a controller. The controller is configured to begin operation of the aerosol generator upon receipt of a signal from the flow sensor indicating that a threshold flow rate has been achieved by a user when inhaling a tidal breath through the mouthpiece, and to stop operation after the passage of an operation time period that is selected such that continuation of the tidal breath delivers substantially all of the aerosol to the lungs.

Abstract: A method for producing an aerosol generator utilizes a vibratable member having a plurality of apertures for producing liquid droplets upon vibration of the vibratable member. A support member is injection molded about the vibratable member, and a vibratable element is placed in vibrational communication with the vibratable member.

Abstract: A method for producing an aerosol generator utilizes a vibratable member having a plurality of apertures for producing liquid droplets upon vibration of the vibratable member. A support member is injection molded about the vibratable member, and a vibratable element is placed in vibrational communication with the vibratable member.

Abstract: A three-way valve assembly having a reciprocable valve plunger movably controlled by a solenoid. The valve housing has an elastomeric orifice member seated thereon, which orifice member controls flow of pressure fluid from a source. The valve plunger has an enlarged nondeformable valve surface thereon which engages a projecting end portion of the orifice member for sealingly closing off the orifice.

Abstract: A control system is disclosed for a hydrostatic transmission of the type including a prime mover driven variable displacement pump, the displacement of which is controlled by a pair of strokers (28, 30). Flow of pressurized control fluid from the charge pump to one of the strokers, and from the other stroker to tank, is controlled by a main control valve (34). The control system includes an auxiliary control valve (44) defining passages (98, 100, 102) communicating between the lines connecting the main control valve and the strokers. The auxiliary control valve includes an on-off, electro-hydraulic valve (46) which prevents flow through the auxiliary valve in response to an electrical signal in one condition, and permits flow in response to an electrical signal in another condition.

Abstract: A control valve assembly (10) is provided for controlling a hydrostatic transmission including a fluid pump having a variable swashplate, a source of control fluid under pressure, and a servo system responsive to the control fluid for varying the swashplate of the fluid pump. The control valve includes a valve body (12), first (26) and second (28) fluid chambers disposed in the valve body, a first fluid passageway (30) disposed in the valve body for directing pressurized control fluid to the first and second fluid chambers and a valve member (16) located in the valve body for controlling the flow of control fluid to the servo system. The pressurized fluid in the first fluid chamber acts on the valve member to bias the valve member in a first direction and the pressurized fluid in the second chamber acts on the valve member to bias the valve member in the second direction opposite the first direction.