Abstract: A system includes a signal generator, configured to pass a generated signal, which has two different generated frequencies, through a circuit including an intrabody electrode. The system further includes a processor, configured to identify, while the generated signal is passed through the circuit, a derived frequency, which is derived from the generated frequencies, on the circuit, and to generate, in response to identifying the derived frequency, an output indicating a flaw in the electrode. Other embodiments are also described.

Abstract: A data resolution system provides users with the ability to access and create associations between data items tagged in documents as part of an initial process of identifying data items to be tagged in the documents. Thus, the user that is adding tags to the documents is able to identify related data items from other data sources and create links with those data sources. This ability to identify links at the time of tagging reduces the need for later searching of data sources for related data items. Additionally, the system automatically stores information regarding each link so that information regarding the linked data items may be viewed alongside the original document and/or further information regarding the linked data item is easily accessible. Data items that are tagged in a document may be associated with data items representing the same object, but with different identifiers, names, etc. in external data sources.

Abstract: Methods and system for operating a thermal storage device of a vehicle system are provided. In one example, a method comprises estimating a temperature of a thermal battery after the battery and coolant included therein have reached thermal equilibrium, and determining a state of charge of the battery based on the estimated temperature and one or more chemical properties of two phase change materials included within the battery. Specifically, the thermal battery may include two phase change materials with different melting points for providing thermal energy to warm coolant in a vehicle coolant system.

Abstract: A method of forming a security device includes: a holographic image layer, diffusion element, and barrier layer. A region of the barrier layer includes a heat-transformable material. The method further includes selectively applying heat at a plurality of positions within the region of the barrier layer, in accordance with a predetermined pattern, so as to modify the heat-transformable material such that the region of the barrier layer is selectively rendered passable to the diffusible substance at each of the plurality of positions, thereby permitting diffusion of the diffusible substance between the regions of the diffusion element and the holographic image layer such that, at a plurality of positions within the region of the holographic image layer and corresponding to the predetermined pattern, the volume hologram is dimensionally modified so as to become viewable in a second observable colour, different from the first observable colour.

Abstract: A data resolution system provides users with the ability to access and create associations between data items tagged in documents as part of an initial process of identifying data items to be tagged in the documents. Thus, the user that is adding tags to the documents is able to identify related data items from other data sources and create links with those data sources. This ability to identify links at the time of tagging reduces the need for later searching of data sources for related data items. Additionally, the system automatically stores information regarding each link so that information regarding the linked data items may be viewed alongside the original document and/or further information regarding the linked data item is easily accessible. Data items that are tagged in a document may be associated with data items representing the same object, but with different identifiers, names, etc. in external data sources.

Abstract: Disclosed are methods for exploiting memory properties of biological systems such as gene regulatory networks (GNRs). The disclosed methods may be utilized in order to treat diseases and disorders and in order to promote health.

Abstract: Disclosed are engineered multicellular organisms. The disclosed organisms comprise an aggregate of ciliated cells, and the organisms move when the ciliated cells are actuated. The engineered multicellular organisms also are capable of kinematic self-replication. The engineered multicellular organisms are capable of moving a plurality of dissociated ciliated cells into piles of ciliated cells which form a multicellular organism comprising an aggregate of ciliated cells which moves when the ciliated cells are actuated. Also disclosed are systems and methods for designing, preparing, and utilizing the engineered multicellular organisms.

Abstract: Aspects of the present application relate to systems and methods for automated web-based filter tuning. The method can include receiving information characterizing a plurality of attributes of a web server and normalizing the received information. The method can include identifying a set of relevant tags to the web server via comparison of the normalized received information to data contained in a tag database, and forming a set of signatures relevant to the web server based at least in part on the set of relevant tags. The method can include receiving an administrator selection of at least some of the set of signatures, enabling the selected at least some of the set of signatures for filtering of received web requests.

Abstract: An assistive device for a metered dose inhaler decreases the force required to operate the inhaler. The assistive device has a body with a passage for receiving a replaceable conventional metered dose inhaler assembly that has a canister and a transverse mouthpiece with an axis of the canister aligning approximately with that of the passage. At least two symmetrically arranged levers extend in a direction away from the body and parallel to an axis thereof. A proximal end of each lever is attached to the body such that the free opposite ends of the levers may be moved towards and away from each other. An inwardly directed cam surface on each of the lever exerts a force on an end of the canister in use to move the canister longitudinally to cause a dose of medicament to be dispensed from the canister. An optional dose counter may form part of the device.

Abstract: Systems and methods are provided for storing a first data object comprising a first set of immutable components, the first data object being associated with a corresponding second data object stored by a remote replication system. A difference is determined between the first set of immutable components of the first data object and a second set of immutable components of the corresponding second data object. A subset of immutable components is identified from the first set of immutable components based on the difference. The subset of immutable components from the first set of immutable components is provided to the remote replication system over a communication network.

Abstract: A method of identifying a subject having a bacterial infection, which includes discriminating said subject from a subject having a viral infection or an inflammatory disease. Also provided is a gene signature employed in the method and to a bespoke gene chip for use in the method. Further provided are probes and/or primers specific to genes in a signature of the present disclosure.

Abstract: A catheter includes a shaft for insertion into an organ of a patient, an extendable distal-end assembly, and two or more strengthening elements. The extendable distal-end assembly is coupled to the shaft and includes multiple splines, at least one spline includes a flexible circuit board having one or more electrodes disposed thereon, the circuit board is configured, when the distal-end assembly is extended in the organ, to conform to a surface of the organ so as to make contact between the electrodes and the surface. The strengthening elements are distributed along the circuit board of the spline and are configured to mechanically strengthen the spline.

Abstract: Described herein are microfluidic devices and systems for high density cell culture and/or high throughput cell assays. Methods of using the same are also provided herein. In some embodiments, the microfluidic devices and systems described herein provide rapid and automated trapping of single embryos in ordered arrays.

Abstract: An assistive device for a metered dose inhaler decreases the force required to operate the inhaler. The assistive device has a body with a passage for receiving a replaceable conventional metered dose inhaler assembly that has a canister and a transverse mouthpiece with an axis of the canister aligning approximately with that of the passage. At least two symmetrically arranged levers extend in a direction away from the body and parallel to an axis thereof. A proximal end of each lever is attached to the body such that the free opposite ends of the levers may be moved towards and away from each other. An inwardly directed cam surface on each of the levers engages a closed end of a canister in use to move the canister longitudinally to cause a dose of medicament to be dispensed from the canister. An optional dose counter may form part of the device.

Abstract: A plurality of control-signal generators are configured to generate respective control signals having respective control-signal amplitudes and different respective control-signal frequencies, and a plurality of signal adders are configured to produce respective composite signals for application to a subject, by adding the control signals to respective ablation signals having respective ablation-signal amplitudes. The control-signal generators are configured to generate the control signals such that respective ratios between the control-signal amplitudes and the ablation-signal amplitudes are constant during the application of the composite signals to the subject.

Abstract: A system includes a signal generator, configured to pass a generated signal, which has two different generated frequencies, through a circuit including a bidirectional semiconductor device. The system further includes a processor, configured to identify, while the generated signal is passed through the circuit, a derived frequency, which derives from the generated frequencies, on the circuit, and to generate, in response to identifying the derived frequency, an output indicating that a property of the bidirectional semiconductor device is asymmetric. Other embodiments are also described.

Abstract: A system includes a signal generator, configured to pass a generated signal, which has two different generated frequencies, through a circuit including an intrabody electrode. The system further includes a processor, configured to identify, while the generated signal is passed through the circuit, a derived frequency, which is derived from the generated frequencies, on the circuit, and to generate, in response to identifying the derived frequency, an output indicating a flaw in the electrode. Other embodiments are also described.

Abstract: Systems and methods are provided for storing a first data object comprising a first set of immutable components, the first data object being associated with a corresponding second data object stored by a remote replication system. A difference is determined between the first set of immutable components of the first data object and a second set of immutable components of the corresponding second data object. A subset of immutable components is identified from the first set of immutable components based on the difference. The subset of immutable components from the first set of immutable components is provided to the remote replication system over a communication network.

Abstract: A signal return-path symmetry measurement apparatus includes a transformer and monitoring circuitry. The transformer is coupled to first and second return-path electrodes that are attached to a body of a patient and serve as a return path for an electrical signal applied to the patient. The transformer is configured to generate a return-path-difference electrical signal responsive to a difference between electrical signals returning from the first and second return-path electrodes. The monitoring circuitry is configured to generate an electrode symmetry measure responsive to the return-path-difference electrical signal.

Abstract: A data resolution system provides users with the ability to access and create associations between data items tagged in documents as part of an initial process of identifying data items to be tagged in the documents. Thus, the user that is adding tags to the documents is able to identify related data items from other data sources and create links with those data sources. This ability to identify links at the time of tagging reduces the need for later searching of data sources for related data items. Additionally, the system automatically stores information regarding each link so that information regarding the linked data items may be viewed alongside the original document and/or further information regarding the linked data item is easily accessible. Data items that are tagged in a document may be associated with data items representing the same object, but with different identifiers, names, etc. in external data sources.