Abstract: Described herein are methods of treating, preventing, or reducing dendritic spine density loss in a subject, the method comprising administering a compound selected from: metformin, pentosan polysulfate, amlexanox, leflunomide, prasterone, glutathione disulfide, pazopanib, bosutinib, dabrafenib, baricitinib, or a pharmaceutically acceptable salt, prodrug, or derivative thereof; or any combination thereof; or compositions described herein.

Abstract: An autonomous rover including a frame having a first end and a second end longitudinally spaced from the first end and forming a payload bay, the payload bay being sized to support a pickface, a common active registration surface configured to engage the pickface, and a drive section connected to the common active registration surface, the drive section being configured to variably position the common active registration surface relative to at least one storage shelf of an automated storage and retrieval system to effect placement of the pickface on the storage shelf so that pickfaces are substantially continuously arranged along the at least one storage shelf with a predetermined storage spacing between the pickfaces.

Abstract: A control system for a double-acting air cylinder of an agricultural implement includes a valve assembly configured to control a base end air pressure and a rod end air pressure of the double-acting air cylinder. The control system also includes a controller communicatively coupled to the valve assembly. The controller is configured to determine a target base end air pressure and a target rod end air pressure based on a target force of the double-acting air cylinder and a target damping factor of the double-acting air cylinder. The controller is also configured to control the valve assembly such that a first difference between the base end air pressure and the target base end air pressure is less than a first threshold value and a second difference between the rod end air pressure and the target rod end air pressure is less than a second threshold value.

Abstract: The present disclosure involves systems, software, and computer implemented methods for automatically providing a lending offer for loyalty points based on a customer account analysis. One example method includes initiating an offer analysis for a customer account associated with a particular customer and storing an account balance and a point deficit balance. The offer analysis determines whether to provide an offer for a point loan, and is based on profile information of the customer, a current point balance, and a reward identified from the loyalty account. If an offer is to be provided, an offer for a loan of points equal to the difference between the current point balance of a loyalty account and the point value cost of the reward is transmitted to a client device of the customer. If accepted, the current point balance and the point deficit are both incremented by the amount of the offer.

Abstract: The present invention relates to shaker doors with solid cores and methods for making the same. The shaker doors contain different core materials at the recessed panel than the raise peripheral region to provide dimensional stability and reduced distortion when the doors are exposed to high humidity. The devices and methods also provide for easy assembly of solid core shaker doors, including fire rated doors.

Abstract: In one aspect, a method for inspecting features of an image using an image inspection controller that includes a processor communicatively coupled to a memory is described. The method includes receiving, at the processor, an input image, performing, on the input image, one of a semantic segmentation process and an object classification process to generate an output image, and prompting a user to select between approving the displayed output image, and at least one of i) performing an additional semantic segmentation process on the displayed output image, and ii) performing an additional object classification process on the displayed output image.

Abstract: A directional vibration control apparatus, which includes a tunable vibration absorber (TVA) for a vibratory compactor machine is provided. The TVA includes a frame mounting structure that is configured to mechanically interface with a frame of the vibratory compactor to provide a fixed attachment of the TVA to the frame of the vibratory compactor, a TVA carrier that extends from the frame mounting structure into an interior portion of a drum of the vibratory compactor machine, a resilient element that includes a first portion that is fixedly attached relative to the TVA carrier and a second portion that includes a degree of freedom of movement relative to the TVA carrier, and a mass that is attached to the second portion of the resilient element and that includes the degree of freedom of movement relative to the TVA carrier.

Abstract: The present invention relates to shaker doors with solid cores and methods for making the same. The shaker doors contain different core materials at the recessed panel than the raise peripheral region to provide dimensional stability and reduced distortion when the doors are exposed to high humidity. The devices and methods also provide for easy assembly of solid core shaker doors, including fire rated doors.

Abstract: A vibration assembly for a surface compactor machine includes a support subassembly connected to the compacting surface of the surface compactor machine. A primary eccentric shaft is disposed around a secondary eccentric shaft, with the primary and secondary eccentric shafts both rotatable about a common axis of rotation. One or more of primary bearing subassemblies is disposed between the primary eccentric shaft and the support subassembly for supporting the primary eccentric shaft during rotation of the primary eccentric shaft. One or more secondary bearing subassemblies is disposed between the secondary eccentric shaft and the primary eccentric shaft for supporting the secondary eccentric shaft during rotation of the primary eccentric shaft.

Abstract: The present invention relates to shaker doors with solid cores and methods for making the same. The shaker doors contain different core materials at the recessed panel than the raise peripheral region to provide dimensional stability and reduced distortion when the doors are exposed to high humidity. The devices and methods also provide for easy assembly of solid core shaker doors, including fire rated doors.

Abstract: A method for operating a tandem motor linear rod pumping apparatus that includes first and second linear mechanical actuator systems each having a motor, and also includes a rod for a sucker-rod pump. The method calls for constructing the first and second linear mechanical actuator systems to operate within a single housing, and simultaneously operating each of the two motors in a manner that imparts reciprocating vertical motion to respective-vertically movable members of the first and second linear mechanical actuator systems. Each motor has a reversibly rotatable element that is operatively connected to the vertically-movable member of its respective linear mechanical actuator system, thus establishing a fixed relationship between the rotational position of the rotatable element and the vertical position of its respective vertically-movable member. The simultaneous operation of the two motors imparts a reciprocating vertical motion to the pump rod of the sucker-rod pump.

Abstract: In one aspect, a method for inspecting features of an image using an image inspection controller that includes a processor communicatively coupled to a memory is described. The method includes receiving, at the processor, an input image, performing, on the input image, one of a semantic segmentation process and an object classification process to generate an output image, and prompting a user to select between approving the displayed output image, and at least one of i) performing an additional semantic segmentation process on the displayed output image, and ii) performing an additional object classification process on the displayed output image.

Abstract: A directional vibration control apparatus, which includes a tunable vibration absorber (TVA) for a vibratory compactor machine is provided. The TVA includes a frame mounting structure that is configured to mechanically interface with a frame of the vibratory compactor to provide a fixed attachment of the TVA to the frame of the vibratory compactor, a TVA carrier that extends from the frame mounting structure into an interior portion of a drum of the vibratory compactor machine, a resilient element that includes a first portion that is fixedly attached relative to the TVA carrier and a second portion that includes a degree of freedom of movement relative to the TVA carrier, and a mass that is attached to the second portion of the resilient element and that includes the degree of freedom of movement relative to the TVA carrier.

Abstract: An oil pumping system to carry oil from an oil sump in a pump housing to an internal oil reservoir in another portion of the pump housing. A top plate is attached to a pump rod and moves in accordance with a reciprocating motion of the pump rod. A bottom plate is below the top plate. A pump mechanism, disposed between the top plate and bottom plate, includes a valve seat that contacts the bottom plate, and an upper portion that contacts the top plate. A first biasing element is configured to urge the valve seat upward away from the bottom plate. A second biasing element is configured to urge the plunger upward away from the valve seat. Upward movement of the pump rod allows oil to flow into the pump mechanism. Downward movement of the pump rod causes the bottom of the valve seat to seal against the bottom plate.

Abstract: The present invention relates to shaker doors with solid cores and methods for making the same. The shaker doors contain different core materials at the recessed panel than the raise peripheral region to provide dimensional stability and reduced distortion when the doors are exposed to high humidity. The devices and methods also provide for easy assembly of solid core shaker doors, including fire rated doors.

Abstract: A vibration assembly for a surface compactor machine includes a support subassembly connected to the compacting surface of the surface compactor machine. A primary eccentric shaft is disposed around a secondary eccentric shaft, with the primary and secondary eccentric shafts both rotatable about a common axis of rotation. One or more of primary bearing subassemblies is disposed between the primary eccentric shaft and the support subassembly for supporting the primary eccentric shaft during rotation of the primary eccentric shaft. One or more secondary bearing subassemblies is disposed between the secondary eccentric shaft and the primary eccentric shaft for supporting the secondary eccentric shaft during rotation of the primary eccentric shaft.

Abstract: The present invention relates to shaker doors with solid cores and methods for making the same. The shaker doors contain different core materials at the recessed panel than the raise peripheral region to provide dimensional stability and reduced distortion when the doors are exposed to high humidity. The devices and methods also provide for easy assembly of solid core shaker doors, including fire rated doors.

Abstract: The present invention relates to shaker doors with solid cores and methods for making the same. The shaker doors contain different core materials at the recessed panel than the raise peripheral region to provide dimensional stability and reduced distortion when the doors are exposed to high humidity. The devices and methods also provide for easy assembly of solid core shaker doors, including fire rated doors.

Abstract: A door pressing system for pressing interior passage doors, exterior entry doors, bi-fold doors, and/or closet doors features a multi-door pressing station including first and second presses, a loading device, and a discharging device. The pressing station is configured to alternatively move the first and second presses into operative alignment with the loading and discharging devices. The press in operative alignment delivers a pressed assembled door to the discharging device and receives an assembled door layup to be pressed from the loading device. The other press that is out of operatively alignment presses an assembled door received therein. Additional methods and systems are also provided.

Abstract: The present invention relates to shaker doors with solid cores and methods for making the same. The shaker doors contain different core materials at the recessed panel than the raise peripheral region to provide dimensional stability and reduced distortion when the doors are exposed to high humidity. The devices and methods also provide for easy assembly of solid core shaker doors, including fire rated doors.