Abstract: A fuel grain for a rocket, the fuel grain having a plurality of layers of fuel grain material, each layer comprising a plurality of concentric circular structures of different diameter fused together to form a central opening therein, wherein the fuel grain material comprises an ignitable substance. The plurality of layers are stacked and joined securely to form a cylindrical fuel grain with the central opening of each one of the plurality of layers aligned to form a combustion unit extending axially through the fuel grain and bounded by a combustion surface, and wherein the fuel grain is configured to permit mixing of heterogenous materials to enhance thrust performance.

Abstract: A method of making a fuel grain for use in a rocket motor, the method comprising blending a first energetic nanoscale metallic compound and a second compound suitable to form a feedstock material for use in an additive manufacturing apparatus, the additive manufacturing apparatus operatively connected to a computing system, that provides additive manufacturing printing instructions to the additive manufacturing apparatus, permitting construction of an autonomously designed and optimized rocket fuel grain section; wherein the stochastic deposition simulation-assisted fuel grain geometries further comprise a plurality of agglutinated layers of solidified fuel grain compound, each layer of the plurality of layers comprising a plurality of blended and radially displaced beads of different radii, said radial displacement optionally optimized via competitive simulation programs, and wherein the system continuously mixes constituent materials in an inline/static mixer, with viscosity controlled via particle size var

Abstract: A method of making a multi-grained fuel grain for a rocket is disclosed, the method comprising the steps of using at least one nozzle to extrude a first propellant in an additive manufacturing process, the first propellant comprising a multi-grained fuel grain, the multi-grained fuel grain forming the at least one void, the at least one void facilitating variation in internal ballistics, forming sensors, said sensors permitting continuous monitoring and continuous modification such that a user controls the ballistics profile of a rocket motor, forming an electrically-controlled second propellant in contact with and operatively coupled to the sensors; and wherein the additive manufacturing process uses at least at least one nozzle to extrude raw materials.

Abstract: A method of making a fuel grain for use in a rocket motor, the method comprising blending a first energetic nanoscale metallic compound and a second compound suitable to form a feedstock material for use in an additive manufacturing apparatus, the additive manufacturing apparatus operatively connected to a computing system, that provides additive manufacturing printing instructions to the additive manufacturing apparatus, permitting construction of an autonomously designed and optimized rocket fuel grain section; wherein the stochastic deposition simulation-assisted fuel grain geometries further comprise a plurality of agglutinated layers of solidified fuel grain compound, each layer of the plurality of layers comprising a plurality of blended and radially displaced beads of different radii, said radial displacement optionally optimized via competitive simulation programs, and wherein the system continuously mixes constituent materials in an inline/static mixer, with viscosity controlled via particle size var

Abstract: A method of making a multi-grained fuel grain for a rocket is disclosed, the method comprising the steps of using at least one nozzle to extrude a first propellant in an additive manufacturing process, the first propellant comprising a multi-grained fuel grain, the multi-grained fuel grain forming the at least one void, the at least one void facilitating variation in internal ballistics, forming sensors, said sensors permitting continuous monitoring and continuous modification such that a user controls the ballistics profile of a rocket motor, forming an electrically-controlled second propellant in contact with and operatively coupled to the sensors; and wherein the additive manufacturing process uses at least at least one nozzle to extrude raw materials.

Abstract: The present invention relates to a combination of an anti-toxin, The present invention relates to a combination of an anti-toxin, an immunomodulator and a component that provides energy to mucosal cells, which may be useful for decreasing effects of Clostridia sp. or coccidia sp based diseases or other enteric diseases or by generally improving gastro intestinal health or function.

Abstract: The present invention relates to scaffold proteins derived from plant cystatins and to nucleic acids encoding them. The scaffolds are highly stable and have the ability to display peptides. The scaffolds are particularly well suited for constructing libraries, e.g., in phage display or related systems. The invention also relates to various uses of the scaffolds, including in therapy, diagnosis, environmental and security monitoring, synthetic biology and research, and to cells and cell cultures expressing the scaffold proteins.

Abstract: Provided herein are glucocorticoid receptor agonist immunoconjugates, glucocorticoid receptor agonists, and methods of using the same.

Abstract: The present invention relates to a combination of an anti-toxin, The present invention relates to a combination of an anti-toxin, an immunomodulator and a component that provides energy to mucosal cells, which may be useful for decreasing effects of Clostridia sp.

Abstract: The present invention relates to a combination of an anti-toxin, The present invention relates to a combination of an anti-toxin, an immunomodulator and a component that provides energy to mucosal cells, which may be useful for decreasing effects of Clostridia sp. or coccidia sp based diseases or other enteric diseases or by generally improving gastro intestinal health or function.

Abstract: Provided herein are glucocorticoid receptor agonist immunoconjugates, glucocorticoid receptor agonists, and methods of using the same.

Abstract: The present invention relates to scaffold proteins derived from plant cystatins and to nucleic acids encoding them. The scaffolds are highly stable and have the ability to display peptides. The scaffolds are particularly well suited for constructing libraries, e.g., in phage display or related systems. The invention also relates to various uses of the scaffolds, including in therapy, diagnosis, environmental and security monitoring, synthetic biology and research, and to cells and cell cultures expressing the scaffold proteins.

Abstract: The present invention relates to scaffold proteins derived from plant cystatins and to nucleic acids encoding them. The scaffolds are highly stable and have the ability to display peptides. The scaffolds are particularly well suited for constructing libraries, e.g., in phage display or related systems. The invention also relates to various uses of the scaffolds, including in therapy, diagnosis, environmental and security monitoring, synthetic biology and research, and to cells and cell cultures expressing the scaffold proteins.

Abstract: A gas turbine engine fuel delivery system includes a mechanically-driven fuel pump, an electrically-driven fuel pump, and an engine control. The mechanically-driven fuel pump is adapted to receive a drive torque from a gas turbine engine draw fuel into its fuel inlet and discharge the fuel from its fuel outlet. The electrically-driven fuel pump has a first fuel inlet/outlet that is in fluid communication with the mechanically-driven fuel pump fuel inlet, and also has a second fuel inlet/outlet. The engine control is responsive to an engine start signal to cause the electrically-driven fuel pump to be temporarily energized to pump fuel from the first fuel inlet/outlet to the second fuel inlet/outlet, and is responsive to an engine shutdown signal to cause the electrically-driven pump to be temporarily energized to pump fuel from the second fuel inlet/outlet to the first fuel inlet/outlet.

Abstract: A gas turbine engine fuel delivery system includes a mechanically-driven fuel pump, an electrically-driven fuel pump, and an engine control. The mechanically-driven fuel pump is adapted to receive a drive torque from a gas turbine engine draw fuel into its fuel inlet and discharge the fuel from its fuel outlet. The electrically-driven fuel pump has a first fuel inlet/outlet that is in fluid communication with the mechanically-driven fuel pump fuel inlet, and also has a second fuel inlet/outlet. The engine control is responsive to an engine start signal to cause the electrically-driven fuel pump to be temporarily energized to pump fuel from the first fuel inlet/outlet to the second fuel inlet/outlet, and is responsive to an engine shutdown signal to cause the electrically-driven pump to be temporarily energized to pump fuel from the second fuel inlet/outlet to the first fuel inlet/outlet.

Abstract: The present invention relates to scaffold proteins derived from plant cystatins and to nucleic acids encoding them. The scaffolds are highly stable and have the ability to display peptides. The scaffolds are particularly well suited for constructing libraries, e.g., in phage display or related systems. The invention also relates to various uses of the scaffolds, including in therapy, diagnosis, environmental and security monitoring, synthetic biology and research, and to cells and cell cultures expressing the scaffold proteins.

Abstract: The present invention relates to a combination of an anti-toxin, The present invention relates to a combination of an anti-toxin, an immunomodulator and a component that provides energy to mucosal cells, which may be useful for decreasing effects of Clostridia sp.

Abstract: Disclosed is a combustion system for a gas turbine engine, which includes a combustor and a plurality of fuel injector nozzles within the combustor. The plurality of fuel injector nozzles include at least one start nozzle and at least of run nozzle, wherein each of the plurality of fuel injector nozzles is a single-circuit fuel injector nozzle. The combustion system further includes a fuel flow directing system to selectively deliver fuel flow to each of the at least one start nozzle and at least one run nozzle, wherein the fuel flow directing system is configured to deliver preferential flow of fuel to the at least one start nozzle during an engine start-up procedure and is further configured to deliver an equalized flow both of the at least one start nozzle and the at least one run nozzle as a total engine fuel flow is near or above an idle setting.

Abstract: This invention seeks to provide means by which transgenic plants harbour within their genome a chimaeric gene which when expressed produces a protein having a cytotoxic effect. Cytotoxicity is achieved by way of a protein or part thereof capable of blocking cellular protein synthesis, such as a maize ribosome inactivating protein or part thereof. The chimaeric gene may comprise a promoter operably linked to a sequence encoding a protein capable of blocking cellular protein synthesis such that the promoter is inducible at and/or adjacent to a target site.

Abstract: A firearm cartridge has a case configured with a relatively straight-walled portion and a shoulder portion for housing a quantity of propellant. The case further includes a neck for retaining a bullet. The straight-walled portion defines a base cavity having an interior base diameter. The interior base diameter is approximately twice or more the neck diameter. The diameter ratios of the base and neck optimize combustion efficiency to reduce heat and acceleration losses. The cartridge body cavity is sized and configured to contain a sufficient quantity of propellant such that igniting the propellant causes formation of a propellant plug having a diameter that is approximately the diameter of the bullet, and wherein the propellant plug shears free from unburned propellant that is disposed adjacent the relatively straight-walled body portion.