Abstract: The invention relates to a method of operating a mechanical seal assembly (1) having a mechanical seal (2) with a rotating sliding ring (3) and a stationary sliding ring (4), defining a sealing gap (5) between the sliding surfaces thereof, comprising the steps of: collecting operating data and/or environmental data of the mechanical seal (2), transmitting the collected operating data and/or environmental data to a digital twin (31) of the mechanical seal (2), simulating and monitoring the operation of the mechanical seal (2) using the digital twin (31) based on the transmitted operating data and/or environmental data of the mechanical seal (2), and retransmitting a simulation result and/or data of the digital twin.

Abstract: Described is an oral thin film comprising at least one matrix layer, wherein the at least one matrix layer comprises at least one pharmaceutically active agent, at least one polyvinyl alcohol and at least one polyvinyl alcohol-polyethylene glycol graft copolymer, a method for producing same, and use thereof as a medicament.

Abstract: The present invention relates to an oral thin film, comprising at least one layer which contains at least one polyvinyl alcohol and tris(hydroxymethyl)aminomethane, and to the use of such an oral thin film as a medicament.

Abstract: An apparatus for generating a virtual image including a display element for generating an image, an optical waveguide for expanding an exit pupil, and an antiglare element, which is arranged after the optical waveguide in the beam path and is configured as a shutter comprising slats, wherein the slats are braced in pre-tensioning equipment outside of a visible region of the apparatus, and rest against a contacting element under pretension.