Abstract: A device for locating an object. The device includes a housing including a first hole. The device also includes a sensor carried by the housing and comprising two or more electrodes that are positioned next to each other to form a substantially circular configuration. The sensor includes a second hole formed in the center of the circular configuration, and the second hole is axially aligned with the first hole.

Abstract: The present invention relates to a method of rapidly detecting genetic variation in individuals by PCR amplification of the locus of interest using allele-specific-oligonucleotides (ASOs), and visualizing the results. In particular, the present invention relates to the detection of genetic polymorphisms in the transthyretin (TTR) gene.

Abstract: Speech recognition may be improved by generating and using a topic specific language model. A topic specific language model may be created by performing an initial pass on an audio signal using a generic or basis language model. A speech recognition device may then determine topics relating to the audio signal based on the words identified in the initial pass and retrieve a corpus of text relating to those topics. Using the retrieved corpus of text, the speech recognition device may create a topic specific language model. In one example, the speech recognition device may adapt or otherwise modify the generic language model based on the retrieved corpus of text.

Abstract: A device for detecting nucleic acids in a biological sample has a sample port, a lysis station and a sample conduit configured to mix a sample and lysis agent to form a sample-lysis mixture, pass the sample-lysis mixture across a solid-state membrane to capture nucleic acids in the biological sample therein, and receive the remainder of the sample-lysis mixture in a waste chamber. The wash station is configured to introduce the wash solution following the sample-lysis mixture, pass the wash solution across the solid-state membrane to purify nucleic acids captured therein, and receive the wash solution from the solid-state membrane in the waste chamber. The elution station is configured to pass the eluent across the solid-state membrane, elute captured nucleic acids from the solid-state membrane, and pass the captured nucleic acids into one or more reaction chambers for amplifying and detecting the captured nucleic acids.

Abstract: The present invention is a sensor device comprising: a housing; a processing unit assembly disposed within the housing, wherein the processing unit comprising a high frequency oscillator, a first voltage meter, a low frequency oscillator, a second voltage meter; a probe having a predetermined shape and profile attached to the processing unit and extending from the housing a predetermined distance; and a first sensing unit integrated into the probe and in electrical communication with the high frequency oscillator and the first voltage meter; a second sensing unit integrated into the probe relative to the first sensing unit and in electrical communication with the low frequency oscillator and the second voltage meter.

Abstract: An example operation may include one or more of transmitting, via a virtual network, a message to a home network informing the home network that a home network subscriber device is roaming on the virtual network, activating, via the virtual network, a mobile subscription for the home network subscriber device on the virtual network, receiving, via the virtual network, a call for the home network subscriber device that is routed from the home network, routing the call from the virtual network to the home network subscriber device with the activated mobile subscription, wherein the routing further comprises executing, via the virtual network, value added services while routing the call from the virtual network to the home network subscriber device, generating, via the virtual network, a record of the executed value added services, and submitting, via the virtual network, the generated record to the home network.

Abstract: A coolant control valve, including: a housing with a first port and a second port; a primary rotary valve disposed within the housing and including a primary body; and a secondary rotary valve disposed within the housing and including a secondary body. The primary rotary valve and the secondary rotary valve are rotatable around the axis of rotation by at least one actuator to a first configuration. In a first configuration of the primary rotary valve and the secondary rotary valve around the axis of rotation: a first straight line, orthogonal to the axis of rotation, passes through the primary body and the first port; and a second straight line, orthogonal to the axis of rotation and co-planar with the first straight line, passes through the secondary body and the second port.

Abstract: Speech recognition may be improved by generating and using a topic specific language model. A topic specific language model may be created by performing an initial pass on an audio signal using a generic or basis language model. A speech recognition device may then determine topics relating to the audio signal based on the words identified in the initial pass and retrieve a corpus of text relating to those topics. Using the retrieved corpus of text, the speech recognition device may create a topic specific language model. In one example, the speech recognition device may adapt or otherwise modify the generic language model based on the retrieved corpus of text.

Abstract: A surgical clip applier and methods for applying surgical clips to a vessel, duct, shunt, etc., during a surgical procedure are provided. In one exemplary embodiment, a surgical clip applier is provided having a housing with a trigger movably coupled thereto and a shaft extending therefrom with opposed jaws formed on a distal end thereof. The trigger is adapted to advance a clip to position the clip between the jaws, and to move the jaws from an open position to a closed position to crimp the clip positioned therebetween. The surgical clip applier can include a variety of features to facilitate use of the device, including features to prevent misalignment of the jaws and clip therebetween, features to protect the jaws, and features to ensure proper closure of the jaws and clip therebetween.

Abstract: A method of suturing a trocar path incision in a tissue of a patient with an obturator includes inserting the obturator through the tissue such that a shaft of the obturator extends through a tissue opening about the trocar path incision and a distal tip of the obturator is positioned within a cavity of the patient. The method also includes directing the suture via a suturing feature with the obturator inserted through the tissue in order to direct the suture relative to the tissue. Furthermore, the method includes closing the tissue opening about the trocar path incision with the suture.

Abstract: A staple cartridge for use with a stapling device that has an actuator that is selectively actuatable in an axial direction and an anvil portion that is selectively movable between open and closed positions is disclosed. Various embodiments of the present invention include a cartridge body that movably supports first and second staple drivers. The staple drivers each support a staple thereon and serve to drive the staples into forming contact with the anvil upon actuation by the actuator. The various embodiments of the present invention enable the final formed heights of the staples to be varied so as to apply various clamping forces and pressures to soft tissue captured within the staples. In at least one embodiment, the staples can include crowns formed thereon which can be utilized to adjust or control the clamping force and/or pressure applied by the staples.

Abstract: The present disclosure is directed to arthroscopic visualization systems and methods. The visualization system can include a camera with a fluid inflow path, wherein a proximal end of the camera is configured to fluidly connect a fluid reservoir to the fluid inflow path. The system can also include a cannula with a lumen, wherein the lumen is configured to be fluidly connected to the fluid inflow path at a distal end of the camera. In addition, the system can also include a scope, wherein the scope is configured to be connected to the distal end of the camera and a portion of the scope is configured to be inserted into the lumen of the cannula.

Abstract: A surgical clip applier and methods for applying surgical clips to a vessel, duct, shunt, etc., during a surgical procedure are provided. In one exemplary embodiment, a surgical clip applier is provided having a housing with a trigger movably coupled thereto and a shaft extending therefrom with opposed jaws formed on a distal end thereof. The trigger is adapted to advance a clip to position the clip between the jaws, and to move the jaws from an open position to a closed position to crimp the clip positioned therebetween. The surgical clip applier can include a variety of features to facilitate use of the device, including features to prevent misalignment of the jaws and clip therebetween, features to protect the jaws, and features to ensure proper closure of the jaws and clip therebetween.

Abstract: The present invention is a sensor device comprising: a housing; a processing unit assembly disposed within the housing, wherein the processing unit comprising a high frequency oscillator, a first voltage meter, a low frequency oscillator, a second voltage meter; a probe having a predetermined shape and profile attached to the processing unit and extending from the housing a predetermined distance; and a first sensing unit integrated into the probe and in electrical communication with the high frequency oscillator and the first voltage meter; a second sensing unit integrated into the probe relative to the first sensing unit and in electrical communication with the low frequency oscillator and the second voltage meter.

Abstract: A system for predicting ideal environmental conditions to grow plants, the system comprising: establishing a connection with at least one sensor; adjusting at least one setting of the at least one sensor; collecting environmental data from the sensor based on the at least one setting; manipulating the collected environmental data, wherein the data is manipulated from a first format to a second format, wherein the second format is readable by a predictive analyzing engine; performing a predictive model manipulation on the manipulated collected environmental data, wherein a future value of the environmental data is calculated; and manipulating a user interface based on the future value of the environmental data.

Abstract: A device includes a secure execution context that is segregated from an operating system of the device. A security application executing in the operating system interfaces with the secure execution context to obtain verified data. The secure execution context may verify that operating system files are free of malware, obtain sensor readings that may be cryptographically signed, verify functioning of a baseband processor, and verify other aspects of the function and security of the device. The verified data may be used for various purposes such as verifying location of the device, training a machine learning model, and the like.