Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: A circuit connector for a humidification system, the system comprising a base unit configured to be engaged by a humidification chamber. The circuit connector comprises an inlet to fluidly connect to an outlet of the humidification chamber to receive humidified gases therefrom, an outlet to sealably connect to or integral with a conduit for directing the humidified gases to a user, and an electrical terminal for electrically coupling the circuit connector to an electrical terminal associated with the base unit. The circuit connector may be releasably and lockably connectable to the outlet of the humidification chamber and/or orientation features may control orientation of component parts of the system as they are assembled.

Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-3 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.

Abstract: A binocular scanning laser ophthalmoscope (SLO) is used to track the fixational eye movement of each of the eyes of a subject. The binocular SLO may include right eye optics for imaging a portion of the retina of the right eye and left eye optics for imaging a portion of the retina of the left eye. Shifts in the imaged portion of the retina with respect to a reference image of the retina may be used to measure and track eye movement. The right eye optics and left eye optics may be separate imaging paths, each with its own bi-directional MEMS scanning mirror and Keplerian telescope. The use of the MEMS scanning mirrors minimizes the size and weight of the binocular SLO.

Abstract: A method of improving the performance of a powder dusting tip delivering powdered diatomaceous earth powder minimizing clogging in powder bulb duster tips through the use of tips with a more free flowing configuration and different spray patterns than the standard tip assembly and a flexible one piece powder dusting tube, which is attached to the tips which connects to reservoir of powder type insect repellents such as diatomaceous earth pesticides, boric acid pesticides, sevin based insecticides, deltamethrin based insecticides, and permethrin based insecticides as well as other powdered insecticides through threaded connections, made from flexible rubber tubing supported by memory wire that allows the powder duster tip to be positioned for hard to reach areas.

Abstract: The present disclosure is a toy that has hexagonal rings with letters on each hexagonal side that can be rotated to spell words that are present on cards that the users views, the hexagonal rings are removable and replaceable on a lift bar that fits into opening the vertical supports, to facilitate the rotating of the letters the inner hexagonal ring is offset from the letters on the outer ring so the letters fall into place, the variety of words that can be spelled are increased with sets of three hexagonal rings, each with their individual colors for their letters, and three sets of cards with words to spell, each with a color corresponding to the color of one of the set of hexagonal rings.

Abstract: The present disclosure is a toy that has hexagonal rings with letters on each hexagonal side that can be rotated to spell words that are present on cards that the users views, the hexagonal rings are removable and replaceable on a lift bar that fits into opening the vertical supports, to facilitate the rotating of the letters the inner hexagonal ring is offset from the letters on the outer ring so the letters fall into place, the variety of words that can be spelled are increased with sets of three hexagonal rings, each with their individual colors for their letters, and three sets of cards with words to spell, each with a color corresponding to the color of one of the set of hexagonal rings.

Abstract: In an embodiment, an electronic data security system improves the security and usability of encrypted electronic data using a symmetric key approach implemented by security engines embedded on operably coupled integrated circuits. Engines paired to integrated circuits in combinations of hardware and software engines implementing security tasks can also be utilized. A first security engine is configured to interface to a second security engine and, using the components of the respective security engines, securely exchange electronic data using symmetric key encryption. The key change instruction configures the second security engine private key for a subsequent transmission.

Abstract: The disclosed invention provides a biofluid collection device configured with an open microfluidic network, which facilitates nanoliter-scale biofluid collection and transport for biosensing applications. In one embodiment, a biofluid sensing device placed on the skin for measuring a characteristic of an analyte in sweat includes one or more biofluid sensors and a hexagonal open microfluidic network biofluid collector. The disclosed collector provides a volume-reduced pathway for sweat biofluid between the one or more sensors and sweat glands when the device is positioned on the skin. In another embodiment, a biofluid collector includes a network of microchannels comprising three or more repeatedly intersecting channels that provide redundant pathways for biofluid transport. Embodiments of the disclosed invention are also directed to highly stable peptide-based self-assembled monolayers (SAM) and methods of making the SAMs.

Abstract: In an embodiment, an electronic data security system improves the security and usability of encrypted electronic data using a symmetric key approach implemented by security engines embedded on operably coupled integrated circuits. Engines paired to integrated circuits in combinations of hardware and software engines implementing security tasks can also be utilized. A first security engine is configured to interface to a second security engine and, using the components of the respective security engines, securely exchange electronic data using symmetric key encryption. The key change instruction configures the second security engine private key for a subsequent transmission.

Abstract: The present invention provides nanostructures that are particularly well suited for delivery of bioactive agents to organs, tissues, and cells of interest in vivo, and for diagnostic purposes. In exemplary embodiments, the nanostructures are complexes of DNA strands having fully defined nucleotide sequences that hybridize to each other in such a way as to provide a pre-designed three dimensional structure with binding sites for targeting molecules and bioactive agents. The nanostructures are of a pre-designed finite length and have a pre-defined three dimensional structure.

Abstract: In some embodiments, a construction project administration system and method are disclosed that queries an administrator as to ownership, construction specifications, bidding parameters etc. for a proposed construction project using active first, second and third level questions and accepts and stores replies to the active questions. The stored replies can be compared to predetermined answers, and questions that become irrelevant based on the answers can be deactivated and taken off a list of questions to be asked. After a sufficient amount of questions are answered, the system can auto-configure a process for online construction management. For example a website can be set up that can be used by all parties to the project to automate communications, the exchange of data, status updates etc. including the submission of bids, acceptance of bids, and the award of contracts and many more paperless construction management features.

Abstract: In some embodiments, a construction project administration system and method are disclosed that queries an administrator as to ownership, construction specifications, bidding parameters etc. for a proposed construction project using active first, second and third level questions and accepts and stores replies to the active questions. The stored replies can be compared to predetermined answers, and questions that become irrelevant based on the answers can be deactivated and taken off a list of questions to be asked. After a sufficient amount of questions are answered, the system can auto-configure a process for online construction management. For example a website can be set up that can be used by all parties to the project to automate communications, the exchange of data, status updates etc. including the submission of bids, acceptance of bids, and the award of contracts and many more paperless construction management features.

Abstract: In some embodiments, a construction project administration system and method are disclosed that queries an administrator as to ownership, construction specifications, bidding parameters etc. for a proposed construction project using active first, second and third level questions and accepts and stores replies to the active questions. The stored replies can be compared to predetermined answers, and questions that become irrelevant based on the answers can be deactivated and taken off a list of questions to be asked. After a sufficient amount of questions are answered, the system can auto-configure a process for online construction management. For example a website can be set up that can be used by all parties to the project to automate communications, the exchange of data, status updates etc. including the submission of bids, acceptance of bids, and the award of contracts and many more paperless construction management features.

Abstract: A method and apparatus for collecting greywater from greywater sources such as bathtubs and showers before the greywater can enter the existing plumbing through a drain, without altering the plumbing, and communicating the greywater to a storage reservoir for use with irrigation landscaping, the apparatus including a drain cover and water inlet, and a pump providing a vacuum force for communicating the greywater through a communication conduit to the storage reservoir.

Abstract: A trailer of the type adapted to be folded from an expanded state to a compact state. The trailer includes a central chassis portion with pivot means at longitudinal ends thereof, as well as a front and rear chassis portion pivotably connected to the central chassis portion through respective front and rear pivot means. When the trailer is in the expanded state, the front chassis portion, rear chassis portion and central chassis portion extend in a substantially horizontal plane, and when the trailer is in the compact state, the front chassis portion and rear chassis portion extend substantially perpendicularly to the central chassis portion. In this state, at least one of the front or rear chassis portions extends at least partially below the central chassis portion to thereby assist in stabilizing the trailer in the compact state.

Abstract: A light-emitting ceramic based panel, hereafter termed “electroceramescent” panel, is herein claimed. The electroceramescent panel is formed on a substrate providing mechanical support as well as serving as the base electrode for the device. One or more semiconductive ceramic layers directly overlay the substrate, and electrical conductivity and ionic diffusion are controlled. Light emitting regions overlay the semiconductive ceramic layers, and said regions consist sequentially of a layer of a ceramic insulation layer and an electroluminescent layer, comprised of doped phosphors or the equivalent. One or more conductive top electrode layers having optically transmissive areas overlay the light emitting regions, and a multi-layered top barrier cover comprising one or more optically transmissive non-combustible insulation layers overlay said top electrode regions.

Abstract: The invention relates to a trailer of the type adapted to be folded from an expanded state to a compact state. The trail includes a central chassis portion (16) with pivot means (42) at longitudinal ends thereof, as well as a front (20) and rear (18) chassis portion pivotally connected to the central chassis portion (16) through respective front and rear pivot means. When the trailer is in the expanded state, the front chassis portion, rear chassis portion and central chassis portion extend in a substantially horizontal plane and when the trailer is in the compact state, the front chassis portion and rear chassis portion extend substantially perpendicularly to the central chassis portion. In this state at least one of the front or rear chassis portions extend at least partially below the central chassis portion to thereby assist in stabilising the trailer in the compact state.

Abstract: Methods for implementing an Internet Operating System are described at the core as a Unified-Dynamic Domain Name Server (UD-DNS) system and may be referred to as a web integrity service (WIS). A list of root http addresses resides in a database. The top level domain (TLD) is parsed from the list. New TLD extensions representing human-based networks of integrity-founded information are bound to the previously parsed second-level domain names and assigned a Registry Identifier Number (RIN). The list is transferred to an authentication registry server. For each new http address/RIN, a dataset component template is imported and encrypted into a global encryption key. A bindery service connects the end-user of the Internet to a validation service through which a dataset component template may be populated and, per each new TLD's entity domain and qualification servers, displayed.