Patents by Inventor Michael A. Pickart

Michael A. Pickart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMORTALIZED HUMAN KERATINOCYTE CELL LINE
    Publication number: 20040265787
    Abstract: A spontaneously immortalized human keratinocyte cell line is disclosed. In a preferred embodiment, this cell line is ATCC 12191. In another embodiment of the invention, a method of assaying the effect of a test tumor cell modulation agent is disclosed. The method comprises the steps of obtaining a human stratified squamous epithelial cell culture, wherein the culture comprises human malignant squamous epithelial cells and spontaneously immortalized human keratinocytes, wherein the culture forms a reconstituted epidermis. One then treats the epidermis with a test tumor cell modulation agent and evaluates the growth of the malignant cells within the epidermis.
    Type: Application
    Filed: November 19, 2002
    Publication date: December 30, 2004
    Inventors: B. Lynn Allen-Hoffmann, Sandra J. Schlosser, Michael A. Pickart
  • Immortalized human keratinocyte cell line
    Publication number: 20030157476
    Abstract: A spontaneously immortalized human keratinocyte cell line is disclosed. In a preferred embodiment, this cell line is ATCC 12191. In another embodiment of the invention, a method of assaying the effect of a test tumor cell modulation agent is disclosed. The method comprises the steps of obtaining a human stratified squamous epithelial cell culture, wherein the culture comprises human malignant squamous epithelial cells and spontaneously immortalized human keratinocytes, wherein the culture forms a reconstituted epidermis. One then treats the epidermis with a test tumor cell modulation agent and evaluates the growth of the malignant cells within the epidermis.
    Type: Application
    Filed: November 19, 2002
    Publication date: August 21, 2003
    Inventors: B. Lynn Allen-Hoffmann, Sandra J. Schlosser, Michael A. Pickart
  • Immortalized human keratinocyte cell line
    Publication number: 20010023061
    Abstract: A spontaneously immortalized human kerazinocyte cell line is disclosed. In a preferred embodiment, this cell line is ATCC 12191. In another embodiment of the invention, a method of assaying the effect of a test tumor cell modulation agent is disclosed. The method comprises the steps of obtaining a human stratified squamous epithelial cell culture, wherein the culture comprises human malignant squamous epithelial cells and spontaneously immortalized human keratinocytes, wherein the culture forms a reconstituted epidermis. One then treats the epidermis with a test tumor cell modulation agent and evaluates the growth of the malignant cells within the epidermis.
    Type: Application
    Filed: January 24, 2001
    Publication date: September 20, 2001
    Inventors: B. Lynn Allen-Hoffmann, Sandra J. Schlosser, Michael A. Pickart
  • Immortalized human keratinocyte cell line
    Patent number: 6214567
    Abstract: A spontaneously immortalized human keratinocyte cell line is disclosed. In a preferred embodiment, this cell line is ATCC 12191. In another embodiment of the invention, a method of assaying the effect of a test tumor cell modulation agent is disclosed. The method comprises the steps of obtaining a human stratified squamous epithelial cell culture, wherein the culture comprises human malignant squamous epithelial cells and spontaneously immortalized human keratinocytes, wherein the culture forms a reconstituted epidermis. One then treats the epidermis with a test tumor cell modulation agent and evaluates the growth of the malignant cells within the epidermis.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: April 10, 2001
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: B. Lynn Allen-Hoffmann, Michael A. Pickart
  • Immortalized human keratinocyte cell line
    Patent number: 5989837
    Abstract: A spontaneously immortalized human keratinocyte cell line is disclosed. In a preferred embodiment, this cell line is ATCC 12191. In another embodiment of the invention, a method of assaying the effect of a test tumor cell modulation agent is disclosed. The method comprises the steps of obtaining a human stratified squamous epithelial cell culture, wherein the culture comprises human malignant squamous epithelial cells and spontaneously immortalized human keratinocytes, wherein the culture forms a reconstituted epidermis. One then treats the epidermis with a test tumor cell modulation agent and evaluates the growth of the malignant cells within the epidermis.
    Type: Grant
    Filed: July 13, 1998
    Date of Patent: November 23, 1999
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: B. Lynn Allen-Hoffmann, Sandra J. Schlosser, Michael A. Pickart