Abstract: The disclosed apparatus may include a holding affordance that is configured to hold an optical element, a beam emitter, and a beam sensor, where the holding affordance is positioned, along a first dimension, between the beam emitter and the beam sensor; a first linear stage that supports the beam emitter and that, when actuated, moves the beam emitter along a second dimension; a first rotational stage that supports the beam emitter and that, when actuated, rotates the beam emitter in a staging plane defined by the first dimension and the second dimension; a second linear stage that supports the beam sensor and that, when actuated, moves the beam sensor along the second dimension; and a second rotational stage that supports the beam sensor and that, when actuated, rotates the beam sensor in the staging plane. Various other systems and methods are also disclosed.

Abstract: Methods and systems of storing and managing regulated content items on a non-regulated storage platform are provided. A representation of a regulated content item representing content of the regulated content item is created. The content of the regulated content item is subject to one or more regulations and the regulated content item is stored on the non-regulated storage platform. The representation of the regulated content item is provided to the non-regulated storage platform for storage. The representation of the regulated content item is configured to be accessible on the non-regulated storage platform. A request to access the regulated content item using the representation of the regulated content item is received. The regulated content item is retrieved from the non-regulated storage platform in response to the received request.

Abstract: An EGR cooler includes an elongated, stainless steel cooler housing with a first end having a stainless steel end plate and a second end opposite the first end, and an Inconel diffuser having an inlet end defining a gas inlet and an outlet end welded to the stainless steel end plate. The stainless steel end plate having a first thickness and the outlet end of the Inconel diffuser including a sidewall having a second thickness that is 50% or less of the first thickness.

Abstract: An EGR cooler includes an elongated, stainless steel cooler housing with a first end having a stainless steel end plate and a second end opposite the first end, and an Inconel diffuser having an inlet end defining a gas inlet and an outlet end welded to the stainless steel end plate. The stainless steel end plate having a first thickness and the outlet end of the Inconel diffuser including a sidewall having a second thickness that is 50% or less of the first thickness.

Abstract: Allowing access to regulated content (e.g., FDA regulated) via mobile devices can increase operational efficiency of companies that have this type of content, and allow users to quickly interact with this content even when outside of the company office. Yet, mobile devices present security issues in ensuring that the integrity of the regulated content is maintained. A regulated content management system applies a multi-step validation and authentication process to allow mobile access to regulated content. The system validates a mobile application installed on the device for regulated content access, the mobile device itself, and the credentials of the user trying to access the content before access is granted. This thus provides users with access to regulated content in a mobile environment while maintaining the integrity of the regulated content.

Abstract: A piston for an internal combustion engine includes a compound piston body having a crown piece joined to a skirt piece by a circumferential weld. The skirt piece is formed of a lower temperature-capable steel such as a low alloy steel, and the crown piece is formed of a higher temperature-capable steel having a martensitic microstructure and containing about 10% wt. or greater of chromium. Related methodology for making a piston is also disclosed.

Abstract: Methods and systems of storing and managing regulated content items on a non-regulated storage platform are provided. A representation of a regulated content item representing content of the regulated content item is created. The content of the regulated content item is subject to one or more regulations and the regulated content item is stored on the non-regulated storage platform. The representation of the regulated content item is provided to the non-regulated storage platform for storage. The representation of the regulated content item is configured to be accessible on the non-regulated storage platform. A request to access the regulated content item using the representation of the regulated content item is received. The regulated content item is retrieved from the non-regulated storage platform in response to the received request.

Abstract: A system stores and manages regulated content items on a non-regulated storage platform. The system creates a representation of a regulated content item representing its content that is subject to one or more regulations. The system provides representation of the regulated content item to the non-regulated storage platform for storage. The representation of the regulated content item is configured to be accessible on the non-regulated storage platform. If the system receives a request to access the regulated content item using the representation of the regulated content item, the system retrieves the regulated content item from the non-regulated storage platform to fulfill the request.

Abstract: Allowing access to regulated content (e.g., FDA regulated) via mobile devices can increase operational efficiency of companies that have this type of content, and allow users to quickly interact with this content even when outside of the company office. Yet, mobile devices present security issues in ensuring that the integrity of the regulated content is maintained. A regulated content management system applies a multi-step validation and authentication process to allow mobile access to regulated content. The system validates a mobile application installed on the device for regulated content access, the mobile device itself, and the credentials of the user trying to access the content before access is granted. This thus provides users with access to regulated content in a mobile environment while maintaining the integrity of the regulated content.

Abstract: A piston for an internal combustion engine includes a compound piston body having a crown piece joined to a skirt piece by a circumferential weld. The skirt piece is formed of a lower temperature-capable steel such as a low alloy steel, and the crown piece is formed of a higher temperature-capable steel having a martensitic microstructure and containing about 10% wt. or greater of chromium. Related methodology for making a piston is also disclosed.

Abstract: Methods and systems of storing and managing regulated content items on a non-regulated storage platform are provided. A representation of a regulated content item representing content of the regulated content item is created. The content of the regulated content item is subject to one or more regulations and the regulated content item is stored on the non-regulated storage platform. The representation of the regulated content item is provided to the non-regulated storage platform for storage. The representation of the regulated content item is configured to be accessible on the non-regulated storage platform. A request to access the regulated content item using the representation of the regulated content item is received. The regulated content item is retrieved from the non-regulated storage platform in response to the received request.

Abstract: Methods and systems of storing and managing regulated content items on a non-regulated storage platform are provided. A request to create a regulated content item of which content is subject to one or more regulations is received. The regulated content item is created. An integrity record associated with the regulated content item based on the content of the regulated content item is created. The regulated content item is provided to the non-regulated storage platform for storage. An integrity of the regulated content item stored on the non-regulated storage platform is verified based at least in part on the integrity record.

Abstract: The present invention relates to novel diacylglycerol acyltransferase genes and proteins, and methods of their use. In particular, the invention describes genes encoding proteins having diacylglycerol acetyltransferase activity, specifically for transferring an acetyl group to a diacylglycerol substrate to form acetyl-Triacylglycerols (ac-TAGS), for example, a 3-acetyl-1,2-diacyl-sn-glycerol. The present invention encompasses both native and recombinant wild-type forms of the transferase, as well as mutants and variant forms. The present invention also relates to methods of using novel diacylglycerol acyltransferase genes and proteins, including their expression in transgenic organisms at commercially viable levels, for increasing production of 3-acetyl-1,2-diacyl-sn-glycerols in plant oils and altering the composition of oils produced by microorganisms, such as yeast, by increasing ac-TAG production.

Abstract: A homogenous, symmetrically dividing population of adherent neural stem cells is obtained from ES cells or foetal or adult brain isolates, using an activator of a signalling pathway downstream of a receptor of the EGF receptor family, optionally in combination with an activator of a signalling pathway downstream of an FGF receptor. The neural stem cell population is highly pure and retains the ability to differentiate into neurons after in excess of 100 passages.

Abstract: A homogenous, symmetrically dividing population of adherent neural stem cells is obtained from ES cells or foetal or adult brain isolates, using an activator of a signalling pathway downstream of a receptor of the EGF receptor family, optionally in combination with an activator of a signalling pathway downstream of an FGF receptor. The neural stem cell population is highly pure and retains the ability to differentiate into neurons after in excess of 100 passages.

Abstract: A homogenous, symmetrically dividing population of adherent neural stem cells is obtained from ES cells or foetal or adult brain isolates, using an activator of a signalling pathway downstream of a receptor of the EGF receptor family, optionally in combination with an activator of a signalling pathway downstream of an FGF receptor. The neural stem cell population is highly pure and retains the ability to differentiate into neurons after in excess of 100 passages.

Abstract: The present invention relates to novel diacylglycerol acyltransferase genes and proteins, and methods of their use. In particular, the invention describes genes encoding proteins having diacylglycerol acetyltransferase activity, specifically for transferring an acetyl group to a diacylglycerol substrate to form acetyl-Triacylglycerols (ac-TAGS), for example, a 3-acetyl-1,2-diacyl-sn-glycerol. The present invention encompasses both native and recombinant wild-type forms of the transferase, as well as mutants and variant forms. The present invention also relates to methods of using novel diacylglycerol acyltransferase genes and proteins, including their expression in transgenic organisms at commercially viable levels, for increasing production of 3-acetyl-1,2-diacyl-sn-glycerols in plant oils and altering the composition of oils produced by microorganisms, such as yeast, by increasing ac-TAG production.

Abstract: An internal combustion engine system includes an engine having an engine housing. The engine system further includes an exhaust system, and a turbine disposed within the exhaust system. A particulate reduction device is disposed in the exhaust system upstream of the turbine. The particulate reduction device includes an exhaust retarder having a flow property which is based at least in part on a residence requirement for combustion of particulates in exhaust gases passing therethrough. The flow property may be a flow restriction property, and the exhaust retarder may include a flow restricting trapping element configured to trap particulates in the exhaust gases. The flow restricting trapping element defines a combustion efficacy to exhaust mass flow and temperature coefficient for the particulate reduction device which is based at least in part on a combustion initiating residence requirement for particulates passing through the particulate reduction device.

Abstract: An internal combustion engine system includes an engine having an engine housing. The engine system further includes an exhaust system, and a turbine disposed within the exhaust system. A particulate reduction device is disposed in the exhaust system upstream of the turbine. The particulate reduction device includes an exhaust retarder having a flow property which is based at least in part on a residence requirement for combustion of particulates in exhaust gases passing therethrough. The flow property may be a flow restriction property, and the exhaust retarder may include a flow restricting trapping element configured to trap particulates in the exhaust gases. The flow restricting trapping element defines a combustion efficacy to exhaust mass flow and temperature coefficient for the particulate reduction device which is based at least in part on a combustion initiating residence requirement for particulates passing through the particulate reduction device.

Abstract: An electrical connection element for providing an electrical connection to a porous material may include a first electrically conductive plate disposed on at least a portion of a first side of the porous material. A second electrically conductive plate may be disposed on at least a portion of a second side of the porous material, opposite to the first side. An electrically conductive material may impregnate the porous material in a region between the first and second electrically conductive plates, and an electrical connector may be attached to at least one of the first and second electrically conductive plates.