Patents by Inventor Michael A. Pratta

Michael A. Pratta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers for graft-versus-host disease
    Patent number: 12360120
    Abstract: Biomarkers are provided that are predictive of a subject's responsiveness to a JAK inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing Graft-Versus-Host Disease.
    Type: Grant
    Filed: October 8, 2020
    Date of Patent: July 15, 2025
    Assignee: Incyte Corporation
    Inventors: Michael D. Howell, Sherry Owens, Michael A. Pratta
  • Biomarkers for graft-versus-host disease
    Patent number: 12203942
    Abstract: Biomarkers are provided that are predictive of a subject's responsiveness to a JAK inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing Graft-Versus-Host Disease.
    Type: Grant
    Filed: October 8, 2020
    Date of Patent: January 21, 2025
    Assignee: Incyte Corporation
    Inventors: Michael D. Howell, Sherry Owens, Michael A. Pratta
  • Biomarkers for graft-versus-host disease
    Patent number: 12099068
    Abstract: Biomarkers are provided that are predictive of a subject's responsiveness to a therapy comprising a JAK inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing Graft-Versus-Host Disease.
    Type: Grant
    Filed: May 20, 2022
    Date of Patent: September 24, 2024
    Assignee: Incyte Corporation
    Inventors: Michael D. Howell, Hao Liu, Michael A. Pratta
  • BIOMARKERS FOR GRAFT-VERSUS-HOST DISEASE
    Publication number: 20230027606
    Abstract: Biomarkers are provided that are predictive of a subject's responsiveness to a therapy comprising a JAK inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing Graft-Versus-Host Disease.
    Type: Application
    Filed: May 20, 2022
    Publication date: January 26, 2023
    Inventors: Michael D. Howell, Hao Liu, Michael A. Pratta
  • Biomarkers for graft-versus-host disease
    Patent number: 11372003
    Abstract: Biomarkers are provided that are predictive of a subject's responsiveness to a therapy comprising a JAK inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing Graft-Versus-Host Disease.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: June 28, 2022
    Assignee: Incyte Corporation
    Inventors: Michael D. Howell, Hao Liu, Michael A. Pratta
  • BIOMARKERS FOR GRAFT-VERSUS-HOST DISEASE
    Publication number: 20210123930
    Abstract: Biomarkers are provided that are predictive of a subject's responsiveness to a JAK inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing Graft-Versus-Host Disease.
    Type: Application
    Filed: October 8, 2020
    Publication date: April 29, 2021
    Inventors: Michael D. Howell, Sherry Owens, Michael A. Pratta
  • BIOMARKERS FOR GRAFT-VERSUS-HOST DISEASE
    Publication number: 20210123931
    Abstract: Biomarkers are provided that are predictive of a subject's responsiveness to a JAK inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing Graft-Versus-Host Disease.
    Type: Application
    Filed: October 8, 2020
    Publication date: April 29, 2021
    Inventors: Michael D. Howell, Sherry Owens, Michael A. Pratta
  • BIOMARKERS FOR GRAFT-VERSUS-HOST DISEASE
    Publication number: 20190331697
    Abstract: Biomarkers are provided that are predictive of a subject's responsiveness to a therapy comprising a JAK inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing Graft-Versus-Host Disease.
    Type: Application
    Filed: April 11, 2019
    Publication date: October 31, 2019
    Inventors: Michael D. Howell, Hao Liu, Michael A. Pratta
  • Assays and peptide substrate for determining aggrecan degrading metallo protease activity
    Patent number: 7223834
    Abstract: This invention is directed to assays to determine the presence or absence of proteins that exhibit aggrecanase or ADMP activity. This invention also relates to peptides that acts as a substrates for ADMPs, their use in various assays to determine the presence or absence of ADMP activity, and their use as inhibitors of ADMP activity.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: May 29, 2007
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Jeffrey A. Miller, Elizabeth C. Arner, Robert A. Copeland, Gary L. Davis, Ruiqin Liu, Michael A. Pratta, Micky D. Tortorella