Abstract: A medical fluid pump has a housing, a front lid pivotably hinged to the housing, and a carrying handle. The carrying handle, which may have a bow-shaped design, is pivotably hinged to two opposing side faces of the housing. The carrying handle is hinged to the housing such that a handle portion of the carrying handle lies, in a swiveled-out state, in a direction of gravity substantially over a center of gravity of the fluid pump.

Abstract: A process is described for purifying insulin and insulin analogs that comprises high-pressure liquid chromatography with an acidic cation exchange medium performed in the presence of a water miscible organic modifier and at an elevated temperature followed by reverse phase chromatography performed in the presence of a water miscible organic modifier and at an elevated temperature.

Abstract: The use of two tandem microfiltration (MF) steps in a process for making recombinant insulin is described. The two MF steps in a single downstream purification unit operation reduce both soluble and insoluble impurities and exchange the insulin product into a suitable buffer for downstream purification.

Abstract: A process is described for purifying insulin and insulin analogs that comprises high-pressure liquid chromatography with an acidic cation exchange medium performed in the presence of a water miscible organic modifier and at an elevated temperature followed by reverse phase chromatography performed in the presence of a water miscible organic modifier and at an elevated temperature.

Abstract: A process is described for purifying insulin and insulin analogs that comprises high-pressure liquid chromatography with an acidic cation exchange medium performed in the presence of a water miscible organic modifier and at an elevated temperature followed by reverse phase chromatography performed in the presence of a water miscible organic modifier and at an elevated temperature.

Abstract: A process is described for purifying insulin and insulin analogs that comprises use of two or more orthogonal chromatographic purification steps in tandem following enzymatic digestion of the propeptide-insulin precursor to remove specific product impurities, improve process consistency, and increase process redundancy in the purification of the insulin or insulin analog, e.g., insulin lispro.

Abstract: The use of two tandem microfiltration (MF) steps in a process for making recombinant insulin is described. The two MF steps in a single downstream purification unit operation reduce both soluble and insoluble impurities and exchange the insulin product into a suitable buffer for downstream purification.

Abstract: A process is described for purifying insulin and insulin analogs that comprises use of two or more orthogonal chromatographic purification steps in tandem following enzymatic digestion of the propeptide-insulin precursor to remove specific product impurities, improve process consistency, and increase process redundancy in the purification of the insulin or insulin analog, e.g., insulin lispro.

Abstract: A process is described for purifying insulin and insulin analogs that comprises high-pressure liquid chromatography with an acidic cation exchange medium performed in the presence of a water miscible organic modifier and at an elevated temperature followed by reverse phase chromatography performed in the presence of a water miscible organic modifier and at an elevated temperature.

Abstract: A method for producing a bent extruded profile that includes extruding a first profile bar having a first lateral formation, extruding a second profile bar having a second lateral formation corresponding in a form-fitting manner to the first lateral formation, and inserting the first lateral formation into the second lateral formation so as to connect the first and second profile bars and to create a form-fitting connection restricting relative movement between the first and second profile bars in all directions except a longitudinal direction of the profile bars. The method also includes bending the connected first and second profile bars using a bending process, wherein after bending, the form-fitting connection restricts relative movement between the first and second profile bars in all directions. In addition, an extruded profile including a first profile bar having a first formation on a first longitudinal side and a second profile bar having a second formation on a second longitudinal side.

Abstract: A method for producing a bent extruded profile that includes extruding a first profile bar having a first lateral formation, extruding a second profile bar having a second lateral formation corresponding in a form-fitting manner to the first lateral formation, and inserting the first lateral formation into the second lateral formation so as to connect the first and second profile bars and to create a form-fitting connection restricting relative movement between the first and second profile bars in all directions except a longitudinal direction of the profile bars. The method also includes bending the connected first and second profile bars using a bending process, wherein after bending, the form-fitting connection restricts relative movement between the first and second profile bars in all directions. In addition, an extruded profile including a first profile bar having a first formation on a first longitudinal side and a second profile bar having a second formation on a second longitudinal side.

Abstract: A fastening device for a folding-top covering of a folding top of an open motor vehicle, having a plug-in profile. The plug-in profile is fastened to the folding-top covering of the folding top. The fastening device also has a folding-top frame part and a receiving channel which is formed on the folding-top frame part. It is possible for the plug-in profile to be plugged into the receiving channel on the folding-top frame part in such a manner that a permanent fixing of the folding-top covering relative to the folding-top frame part can be produced.

Abstract: The invention relates to an unlocking device for a vehicle convertible top, comprising a handle for actuating the unlocking device, and at least one locking hook which locks the vehicle convertible top and is operatively connected to the handle by means of an actuating arrangement, a signal generator being provided which detects the position of the handle and which generates a signal when the handle is shifted by a predetermined extent, and the signal causing a catch to be released, preventing further shifting of the handle beyond the predetermined extent.

Abstract: The invention relates to a fastening device for a folding-top covering of a folding top of an open motor vehicle, comprising a plug-in profile, said plug-in profile being fastened to said folding-top covering of the folding top, a folding-top frame part and a receiving channel which is formed on said folding-top frame part, it being possible for said plug-in profile to be plugged into the receiving channel on said folding-top frame part in such a manner that a permanent fixing of said folding-top covering relative to said folding-top frame part can be produced.

Abstract: The invention relates to an unlocking device for a vehicle convertible top, comprising a handle for actuating the unlocking device, and at least one locking hook which locks the vehicle convertible top and is operatively connected to the handle by means of an actuating arrangement, a signal generator being provided which detects the position of the handle and which generates a signal when the handle is shifted by a predetermined extent, and the signal causing a catch to be released, preventing further shifting of the handle beyond the predetermined extent.