Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: Methods, systems and techniques for the accurate measurement breath-borne biomarkers are disclosed. Such methods, systems and techniques may be used for the purposes of detection and/or measurement in breath samples of biomarkers.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 216, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: A portable operating device for controlling a kitchen appliance from different operating positions having a base body, at least one control element, which is displaceable relative to the base body, for the user to input control information, at least one sensor for detecting a relative movement between the at least one control element and the base body, and a communication unit which is connected to the at least one sensor in a signal-transmitting manner in order to wirelessly transmit, to the kitchen appliance, control information which correlates with the relative movement.

Abstract: A process for the production of a fluorinated quartz glass including the steps of generating SiO2 particles in a synthesis burner; depositing the resulting SiO2 particles into a body; and vitrifying the resulting body, wherein a fluorinating agent having a boiling point greater than or equal to ?10° C. is supplied to the synthesis burner.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: Methods are known for producing an anti-resonant hollow-core fiber which has a hollow core extending along a fiber longitudinal axis and an inner jacket region that surrounds the hollow core, said jacket region comprising multiple anti-resonant elements. The known methods have the steps of: providing a cladding tube that has a cladding tube inner bore and a cladding tube longitudinal axis along which a cladding tube wall extends that is delimited by an interior and an exterior; providing a number of tubular anti-resonant element preforms; arranging the anti-resonant element preforms at target positions of the interior of the cladding tube wall, thereby forming a primary preform which has a hollow core region and an inner jacket region; further processing the primary preform in order to form a secondary preform, including an elongation process; and drawing the secondary preform in order to form the hollow-core fiber.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO:1 to SEQ ID NO:113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.

Abstract: Polymer compositions comprising stiff and tough star shaped styrene butadiene block-copolymers A1 and A2 can be used for making shrink films. Block copolymer A2 preferably has the structure with hard blocks Se and Si, hard random copolymer blocks (B/S)Ae, soft random copolymer blocks (B/S)B coupled by a coupling agent X.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for machine translation using neural networks. In some implementations, a text in one language is translated into a second language using a neural network model. The model can include an encoder neural network comprising a plurality of bidirectional recurrent neural network layers. The encoding vectors are processed using a multi-headed attention module configured to generate multiple attention context vectors for each encoding vector. A decoder neural network generates a sequence of decoder output vectors using the attention context vectors. The decoder output vectors can represent distributions over various language elements of the second language, allowing a translation of the text into the second language to be determined based on the sequence of decoder output vectors.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for machine translation using neural networks. In some implementations, a text in one language is translated into a second language using a neural network model. The model can include an encoder neural network comprising a plurality of bidirectional recurrent neural network layers. The encoding vectors are processed using a multi-headed attention module configured to generate multiple attention context vectors for each encoding vector. A decoder neural network generates a sequence of decoder output vectors using the attention context vectors. The decoder output vectors can represent distributions over various language elements of the second language, allowing a translation of the text into the second language to be determined based on the sequence of decoder output vectors.

Abstract: A piece of seating furniture having a seat part, a back part, a chassis, and an at least two-part leg rest pivotably. The parts of the leg rest can be slid relative to each other during the pivoting. A part of the leg rest is formed by a telescoping leg-rest element which is retracted when the leg rest is pivoted in and is extended, in order to increase the length of the leg rest, when the leg rest is pivoted out. A first articulated lever and a second articulated lever are articulated to the seat part, a third articulated lever and a fourth articulated lever are each connected to a fifth articulated lever. A coupling lever and a control lever are articulated to the first articulated lever and/or the second articulated lever and/or to the third articulated lever and/or the fourth articulated lever.

Abstract: A seating furniture item with an adjustable-inclination seat part, a back part, a chassis and an at least two-piece leg support connected pivotably on the seat part and/or on the chassis, wherein the parts of the leg support can be displaced relative to one another during pivoting. A part of the leg support is formed by way of a telescopic leg support element which is retracted when the leg support is pivoted in and is extended in order to increase the length of the leg support when the leg support is pivoted out. By way of a first part stroke, a linear actuator brings about a displacement of the seat part relative to the chassis and a simultaneous inclination adjustment of the seat part, wherein no pivoting out or in of the leg support relative to the seat part takes place during this first part stroke of the linear actuator.