Abstract: The present disclosure provides antibodies to V-domain Ig-containing Suppressor of T cell Activation (VISTA) and compositions comprising such antibodies. Also provided are methods of using antibodies that specifically binds to VISTA to treat diseases, e.g., to treat cancer.

Abstract: A method of applying a paint film to a substrate may include wetting a surface of the substrate or an adhesive layer of a paint film to form a fluid layer thereon. The paint film may further comprise a polymer film layer. The method may further include applying the paint film to the substrate such that the fluid layer is positioned between the adhesive layer and the surface. The applied paint film may be heated with infrared heat to facilitate the removal of the fluid layer and adhere the adhesive layer to the surface. Systems and devices for applying a paint film to a substrate are also disclosed.

Abstract: In some aspects, the techniques described herein relate to a motor vehicle assembly, including: a roof including a recess; a rail, wherein the rail is moveable between a retracted position and a deployed position, wherein the rail is at least partially within a recess of the roof in the retracted position, wherein the rail is able to connect to an accessory arranged above the roof in the deployed position; and a joint assembly, wherein the joint assembly is configured to guide movement of the rail between the retracted position and the deployed position, wherein the joint assembly includes a first foot, a second foot, and a slotted track, and wherein the first foot and the second foot are arranged at least partially within the slotted track.

Abstract: Methods of operating a refrigerator appliance are provided. The refrigerator appliance includes a cabinet defining a food storage chamber with a drawer slidably mounted within the food storage chamber. The refrigerator appliance also includes a sensor operable to detect an atmospheric condition within the food storage chamber of the drawer and a camera assembly positioned and configured for monitoring the drawer. The methods generally include obtaining an image using the camera assembly and analyzing the image to identify a first food item and a second food item in the food storage chamber of the drawer.

Abstract: Embodiments relate to a system and method for managing energy consumption of one or more processor cores in a multicore processing device. The method includes establishing a temporal interval that includes a plurality of temporal periods and an interval energy target for one or more processor cores. The method also includes determining for each temporal period a period energy target for the processor cores and determining a processor core throttling state for the processor cores. The method further includes adjusting the respective period energy target and the respective processor core throttling state at the beginning of each successive temporal period. The method also includes converging, subject to the adjusting, as each respective temporal period of the plurality of temporal periods is concluded, a total period energy consumption of the processor cores with the interval energy target.

Abstract: A processing system receives a user-generated media recording, and metadata associated with the user-generated feedback, from a first device. The user-generated media recording is a recording of the public end-user captured during a live media broadcast using a public-user interface on the first device. The metadata includes information linking the user-generated media recording to the live media broadcast. The system stores the user-generated media recording and the first metadata in one or more storage devices, and transmits a version of the user-generated media recording and at least a portion of the first metadata to a private-user interface on a second device. The private-user interface is configured to receive input from a private end-user selecting the version of the user-generated media recording for broadcast during the same live media broadcast during which the user-generated media recording was created.

Abstract: Provided is a nucleic acid comprising a recombinant bacterial or archaeal geranyl pyrophosphate synthase (GPPS) gene, codon optimized for production in yeast. Also provided is a yeast cell comprising an expression cassette comprising the above nucleic acid. Additionally provided is a method of producing a terpene or cannabinoid in a yeast, the method comprising incubating the above yeast cell in a manner sufficient to produce the terpene or cannabinoid.

Abstract: Hybrid nanomaterials, methods of making the nanomaterials, and methods of using the nanomaterials to detect hydrogen gas.

Abstract: A monitoring system is configured to monitor an environment within an enclosure of a heating, ventilation, air conditioning, and/or refrigeration (HVAC&R) system. The monitoring system includes a sensor configured to acquire data indicative of an environmental parameter value within the enclosure. The monitoring system also includes a controller configured to receive the data from the sensor, to determine occurrence of a thermal event within the enclosure based on the data, and to instruct a circuit breaker of the HVAC&R system to transition to a fault configuration in response to determining the occurrence of the thermal event.

Abstract: A fluid end assembly comprising a housing having multiple conduits formed therein. A tubular sleeve is installed within one of the conduits and is configured to house a plurality of packing seals. A seal is installed within a groove formed in the walls of the housing surrounding the tubular sleeve such that the seal engages an outer surface of the tubular sleeve.

Abstract: A display device comprises a waveguide configured to guide light in a lateral direction parallel to an output surface of the waveguide. The waveguide is further configured to outcouple the guided light through the output surface. The display device additionally comprises a broadband adaptive lens assembly configured to incouple and to diffract therethrough the outcoupled light from the waveguide. The broadband adaptive lens assembly comprises a first waveplate lens comprising a liquid crystal (LC) layer arranged such that the waveplate lens has birefringence (?n) that varies in a radially outward direction from a central region of the first waveplate lens and configured to diffract the outcoupled light at a diffraction efficiency greater than 90% within a wavelength range including at least 450 nm to 630 nm. The broadband adaptive lens assembly is configured to be selectively switched between a plurality of states having different optical powers.

Abstract: Systems, computer program products, and methods are described herein for generating information security management packages through malware tracing, logging, and analysis. A system in accordance with embodiments of the present invention may be configured for receiving one or more trace log files from one or more artifact data collection computing systems; parsing the artifact data and metadata to identify one or more relationships between the target malware and one or more malware artifacts; based on parsing the artifact data and metadata, generating one or more nodes within a malware graph database; and executing a coverage analysis of an information security management package configured to detect a presence of the target malware.

Abstract: The invention provides cellular compositions that contain CD34+ cells derived from bone marrow of a decease donor and CD3+ cells derived from non-bone marrow of the deceased donor. The compositions are useful to promote mixed chimerism in recipients of solid organ transplants. The invention also provides methods of making and using such compositions. In certain embodiments, the invention further provides methods of analyzing and preparing blood and blood components from a deceased donor for use in compositions of the invention to promote mixed chimerism in solid organ transplant recipients.

Abstract: Systems and methods are provided for improving signal propagation using lasers. A laser device is used to clear the air between a first fixed station, such as a base station, and a second fixed station, such as a fixed wireless access device. In the wake of the laser, particles in the air interface are cleared along a path that can then be used to communicate one or more sets of wireless signals. In the wake of the laser, the wireless signals experience less absorption, reflection, and refraction, reducing path loss, and increasing the overall effectiveness of the wireless system—particularly at or near the cell edge or when a meteorological condition exists between the fixed stations.

Abstract: A device may receive network data from base stations associated with a network and may aggregate the network data to generate aggregated network data. The device may remove data that satisfies a threshold from the aggregated network data to generate a reduced set of the aggregated network data. The device may divide the reduced set of the aggregated network data into groups of network factors associated with determining network parameters for the base stations. The device may apply weights to the network factors in the groups of network factors to generate groups of weighted network factors and may generate baselines for the network parameters based on the groups of weighted network factors. The device may compare the network data and the baselines to identify one or more anomalies in the network parameters and may perform one or more actions based on the one or more anomalies.

Abstract: A faceplate of a showerhead has a bottom side that faces a plasma generation region and a top side that faces a plenum into which a process gas is supplied during operation of a substrate processing system. The faceplate includes apertures formed through the bottom side and openings formed through the top side. Each of the apertures is formed to extend through a portion of an overall thickness of the faceplate to intersect with at least one of the openings to form a corresponding flow path for process gas through the faceplate. Each of the apertures has a cross-section that has a hollow cathode discharge suppression dimension in at least one direction. Each of the openings has a cross-section that has a smallest cross-sectional dimension that is greater than the hollow cathode discharge suppression dimension.

Abstract: Mobile management method, system and client. Method includes receiving a DNS query for a host name from an application on client; retrieving reputation data associated with host name from a local cache on client; and determining a policy based on host name and the reputation data. Based on determined policy for the host name, blocking attempted network flows to a host corresponding to host name to produce blocked attempted network flows. Method also includes sending attempted network flow metadata related to the blocked attempted network flows to a collector on client; transmitting the attempted network flow metadata from the collector to a VPN server pool via a VPN tunnel; and producing an anomaly report from the transmitted attempted network flow metadata. The anomaly report includes at least one of anomalies, cohorts, trends, location boundaries, detected network security issues, detected compromised clients and/or optimized network usage.

Abstract: The application relates to a compound having Formula X: which modulates the activity of HER2 and/or a mutant thereof, and/or EGFR and/or a mutant thereof, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which HER2 and/or a mutant thereof, and/or EGFR and/or a mutant thereof, plays a role.

Abstract: At a managed control plane service, constituent services and operational requirements of an application are identified. In response to an end-user request directed to the application, contents of an inter-service request are generated at a resource selected by the managed control plane service for a first constituent service, and a response to the message is generated at another resource selected for a second constituent service. Tasks to be performed for the operational requirements are initiated by the managed control plane service.