Abstract: The invention provides agonistic anti-human VISTA antibodies and antibody fragments. These agonist antibodies and antibody fragments may be used to potentiate or enhance or mimic VISTA's suppressive effects on T cell immunity and thereby suppress T cell immunity. These agonist antibodies and antibody fragments are especially useful in the treatment of autoimmunity, allergy, inflammatory conditions, GVHD, sepsis and transplant recipients. Screening assays for identifying these agonists are also provided.

Abstract: N-Acylated histidine dipeptides of formula are disclosed. The compounds are useful for treating breast cancer.

Abstract: A system for applying a first coating composition and a second coating composition is provided herein. The system includes an atomizing applicator and a high transfer efficiency applicator defining a nozzle orifice. The system further includes a substrate assembly comprising a metal-containing substrate and a plastic-containing substrate. The metal-containing substrate is coupled to the plastic-containing substrate. The atomizing applicator is configured to apply the first coating composition to the metal-containing substrate. The high transfer efficiency applicator is configured to expel the second coating composition through the second nozzle orifice to the plastic-containing substrate.

Abstract: Methods to compute glycemia tests and applications thereof are described. Additional methods to compute risk of atherosclerotic cardiovascular disease and applications thereof are described. Generally, systems utilize analyte measurements to determine a glycemic status or cardiovascular disease risk, which can be used as a basis to treat individuals.

Abstract: The invention provides antagonistic and agonistic anti-human VISTA antibodies and antibody fragments. These antagonist antibodies and antibody fragments may be used to inhibit or block VISTA's suppressive effects on T cell immunity and thereby promote T cell immunity. These agonist antibodies and antibody fragments may be used to potentiate or enhance or mimic VISTA's suppressive effects on T cell immunity and thereby suppress T cell immunity. These antagonist antibodies and antibody fragments are especially useful in the treatment of cancer and infectious conditions. These agonist antibodies and antibody fragments are especially useful in the treatment of autoimmunity, allergy, inflammatory conditions, GVHD, sepsis and transplant recipients. Screening assays for identifying these agonists are also provided.

Abstract: The description relates to representing acoustic characteristics of real or virtual scenes. One method includes generating directional impulse responses for a scene. The directional impulse responses can correspond to sound departing from multiple sound source locations and arriving at multiple listener locations in the scene. The method can include processing the directional impulse responses to obtain coherent sound signals and incoherent sound signals. The method can also include encoding first perceptual acoustic parameters from the coherent sound signals and second perceptual acoustic parameters from the incoherent sound signals, and outputting the encoded first perceptual acoustic parameters and the encoded second perceptual acoustic parameters.

Abstract: A process for reducing the likelihood of or correcting dysphotopsia from intraocular lens implant surgery. The process includes a step of scanning the eye of a patient in need of the intraocular lens implant surgery using a noninvasive echo-locating instrument for obtaining nasal retina information about the eye. Based at least in part from the nasal retina information, a prophylactic measure can be recommended prior to cataract removal surgery, or a corrective measure can be recommended to address the dysphotopsia after the cataract removal surgery. Use of artificial intelligence as part of the process is also contemplated.

Abstract: A system for examining an animal that includes a kiosk housing having an analysis zone. The system includes a persuasion delivery device in the analysis zone. The system includes a dispensing machine to dispense an animal attractant to the persuasion delivery device. The system includes a set of sensors located in the analysis zone to sense real-time data related to health of an animal. The set of sensors includes at least one sensor to sense within the analysis zone at least one biological parameter of the animal related to the health. A method is provided using the system that autonomously guides the animal to the analysis zone by a predisposition of the animal to hunt for an animal attractant so that biological parameters of the animal related to the health of the animal are sensed in a stress-free or reduced stress environment.

Abstract: This document relates to the compressing and/or decompressing of spatial data. A block of spatial data can be compressed by iteratively performing compression iterations on portions of the block and splitting the portions into further portions until compression is completed. The compressed data can include first encoded values indicating whether matches were obtained for comparisons to test values during the compression iterations. The compressed data can also include second encoded values reflecting results of one or more modifications performed on the test values during the compression iterations.

Abstract: Frozen un-proofed dough pieces are produced by pinching an upper skin of an un-proofed dough body to a lower skin and producing a score through the upper skin prior to freezing. The un-proofed dough pieces are formed by mass production, with an un-proofed dough sheet being cut to form dough strips which are then cut into the un-proofed dough pieces, with the score for each un-proofed dough piece being formed either before, during or after the individual un-proofed dough pieces are actually created, but before freezing.

Abstract: A system that includes at least one processor and a non-transitory, tangible memory device having programming instructions. When the instructions are executed by the at least one processor, the at least one processor receives from a set of sensors at least one biological parameter of an animal in a walk-in analysis zone to create real-time biological. The at least one processor analyzes the real-time biological data from the walk-in analysis zone and recommends animal feed nutrients based on the analyzed real-time biological data. The at least one processor communicates the recommended animal feed nutrients to at least one of: a mobile communication device; and a display device in proximity to the walk-in analysis zone.

Abstract: An orientation indicator device that includes a band having an interior side, an exterior side, and a length to wrap around a neck of an animal. The orientation indicator device includes at least one fiducial marker attached to the band that is visible from the exterior side of the band to denote an orientation of the animal. The orientation indicator device includes a tag coupled to the band to hang by gravity from under the neck. The band is in the form of a collar with fasteners to fasten the collar around the neck. A system is also disclosed that includes a walk-in analysis zone. The orientation indicator device and a computer vision system, in the walk-in analysis zone, identify an orientation of an animal in the zone by capturing the orientation indicator device and dimensions of a body of the animal.

Abstract: A system that includes a persuasion delivery device to deliver a persuasion to an animal to persuade the animal into a walk-in analysis zone for conducting an examination session. The system includes a set of sensors to sense in real-time at least one biological parameter to create real-time biological data. Each sensor has a sample collector in the walk-in analysis zone to capture a respective biological parameter. The system includes at least one processor to analyze the real-time biological data and at least one of: recommending animal feed nutrients based on the analyzed real-time biological data; identifying the at least one biological parameter on a user interface; and causing a feed making machine to make animal feed based on the recommended animal feed nutrients.

Abstract: The disclosed embodiments provide systems and methods for providing real-time warnings to merchants for data breaches. For example, the system may include one or more memory devices storing instructions and one or more processors configured to perform operations consistent with this disclosure. The operations may include collecting and storing transaction authorization requests from one or more merchants. The transaction authorization requests may include a virtual account number associated with an account, the virtual account number being previously bound to a merchant and reusable only for the bound merchant. The operations may further include detecting an event at the bound merchant based on, for example, a transaction authorization request having a mismatch between a transacting merchant and the bound merchant. The operations my further include communicating notification of the event through a communication interface with the bound merchant.

Abstract: A dividable dough sheet piece gives consumers enhanced flexibility in creating food items from pre-made sheeted dough. The dividable dough sheet piece is cut from a dough sheet, with the dividable dough sheet piece having a perimeter and including a plurality of interconnected, sub-pieces defined within the perimeter. Each sub-piece is defined by one or more lines of structural weakness that provide predetermined breaking points. The dividable dough sheet piece can be used as a whole or can be divided into the sub-pieces for alternative use.

Abstract: An elastic nonwoven material includes a first non-woven fabric including a plurality of rows. Each row has a plurality of adjacent bonds formed therein. The elastic nonwoven material also includes a first elastic strand entrapped between a first pair of adjacent bonds within a first row of the plurality of rows, and a second elastic strand entrapped between a second pair of adjacent bonds within the first row. A third pair of adjacent bonds within the first row is free of elastic material therebetween and is located between the first pair of adjacent bonds and the second pair of adjacent bonds.

Abstract: The description relates to representing acoustic characteristics of real or virtual scenes. One method includes generating directional impulse responses for a scene. The directional impulse responses can correspond to sound departing from multiple sound source locations and arriving at multiple listener locations in the scene. The method can include processing the directional impulse responses to obtain coherent sound signals and incoherent sound signals. The method can also include encoding first perceptual acoustic parameters from the coherent sound signals and second perceptual acoustic parameters from the incoherent sound signals, and outputting the encoded first perceptual acoustic parameters and the encoded second perceptual acoustic parameters.

Abstract: The disclosed embodiments provide systems and methods for providing real-time warnings to merchants for data breaches. For example, the system may include one or more memory devices storing instructions and one or more processors configured to perform operations consistent with this disclosure. The operations may include collecting and storing transaction authorization requests from one or more merchants. The transaction authorization requests may include a virtual account number associated with an account, the virtual account number being previously bound to a merchant and reusable only for the bound merchant. The operations may further include detecting an event at the bound merchant based on, for example, a transaction authorization request having a mismatch between a transacting merchant and the bound merchant. The operations my further include communicating notification of the event through a communication interface with the bound merchant.

Abstract: An automated storage and retrieval system that coordinates two or more vertical lift modules, each having an elevator system, into a single vertical lift assembly. A first vertical lift module is positioned next to, and offset vertically from, an independent second vertical lift module. A content transfer section is disposed between the two vertical lift modules that is accessible by the elevator system of each vertical lift module. Alternatively, trays can be transferred directly from one elevator system to another elevator system.

Abstract: Disclosed herein are automated processes and systems for determining an underlying cause of anemia. Also disclosed herein are processes and systems for determining an underlying cause of microcytic anemia, normocytic anemia, and macrocytic anemia. Additionally disclosed herein are methods of treating the underlying cause of anemia in an individual in need thereof.