Patents by Inventor Michael A. Stier

Michael A. Stier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Renin inhibitors III
    Patent number: 4895834
    Abstract: The invention concerns novel renin-inhibitory peptides which are useful for treating renin associated hypertension, hyperaldosternoism, and congestive heart failure. Processes for preparing the peptides, compositions containing them and methods of using them are included. Also included is a diagnostic test using the compounds to determine the presence of renin-associated hypertension or hyperaldosteronism.
    Type: Grant
    Filed: November 2, 1987
    Date of Patent: January 23, 1990
    Assignee: Warner-Lambert Company
    Inventors: James P. Hudspeth, James S. Kaltenbronn, Joseph T. Repine, William H. Roark, Michael A. Stier
  • Renin inhibitors
    Patent number: 4743585
    Abstract: The invention concerns novel renin-inhibitory peptides which are useful for treating renin associated hypertension and for treating hyperaldosteronism. Novel intermediates, processes for preparing both the intermediates and the novel peptides, pharmaceutical compositions, and methods of treatment are included.
    Type: Grant
    Filed: November 21, 1986
    Date of Patent: May 10, 1988
    Assignee: Warner-Lambert Company
    Inventors: James P. Hudspeth, James S. Kaltenbronn, Elizabeth A. Lunney, Joseph T. Repine, W. Howard Roark, Michael A. Stier, Francis J. Tinney, Peter W. K. Woo, Ernest D. Nicolaides
  • Renin inhibitors III
    Patent number: 4735933
    Abstract: The invention concerns novel renin-inhibitory peptides which are useful for treating renin associated hypertension and hyperaldosteronism. Processes for preparing the peptides, compositions containing them and methods of using them are included. Also included is a diagnostic test using the compounds to determine the presence of renin-associated hypertension or hyperaldosteronism.
    Type: Grant
    Filed: December 15, 1986
    Date of Patent: April 5, 1988
    Assignee: Warner-Lambert Company
    Inventors: James P. Hudspeth, James S. Kaltenbronn, Joseph T. Repine, W. Howard Roark, Michael A. Stier
  • Separation of diastereomers
    Patent number: 4681972
    Abstract: The S,S-isomers of Boc-benztine and Boc-cyclotine can be produced via the fractional crystallization of R-(+)-alpha-methylbenzylamine salt(s). The products are useful in the production of renin inhibitors.
    Type: Grant
    Filed: September 16, 1986
    Date of Patent: July 21, 1987
    Assignee: Warner-Lambert Company
    Inventors: James S. Kaltenbronn, Michael A. Stier