Abstract: A cellular wheel sluice for granulate bulk product has a housing in which a cellular wheel is rotatably mounted, wherein the housing has an inlet duct for the bulk product, wherein at least two raised granulate roofs are arranged at the inlet duct, wherein a granulate groove is arranged respectively at the transition between two granulate roofs and/or at the transition between one granulate roof and an inlet edge, wherein two granulate grooves in each case run together at an intersection point in the rotation direction of the cellular wheel.

Abstract: A U-shaped band to attach or snap a conduit or pipe to a slotted structural member. The U-shaped band includes a bottom portion, a first side having a first arm connected to the bottom portion; a second side having a second arm connected to the bottom portion thereby forming a U-shaped structure with the first and second sides. The at least one arm snaps into a slot of the slotted structural member when in an engaged position. The slotted structural member may be a strut or a receiver. The receiver has arms to engage and snap into curled ends or lips on sides of the strut and thus may adapt the band to the strut. Alternatively, the band may snap into suitably sized slots on the slotted structural member.

Abstract: Gene-modified, lymphoid-tissue-homing dendritic cells that comprise a 1-alpha-hydroxylase gene and a retinaldehyde dehydrogenase 2 gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme and the retinaldehyde dehydrogenase 2 gene is expressed to produce functional retinaldehyde dehydrogenase 2 gene enzyme. A method for treating one or more than one inflammation-related condition or disease, the method comprising administering gene-modified, lymphoid-tissue-homing dendritic cells that comprise a 1-alpha-hydroxylase gene and a retinaldehyde dehydrogenase 2 gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme and the retinaldehyde dehydrogenase 2 gene is expressed to produce functional retinaldehyde dehydrogenase 2 gene enzyme.

Abstract: A method for fragmenting a genome is provided. In certain embodiments, the method comprises: (a) combining a genomic sample containing genomic DNA with a plurality of Cas9-gRNA complexes, wherein the Cas9-gRNA complexes comprise a Cas9 protein and a set of at least 10 Cas9-associated guide RNAs that are complementary to different, pre-defined, sites in a genome, to produce a reaction mixture; and (b) incubating the reaction mixture to produce at least 5 fragments of the genomic DNA. Also provided is a composition comprising at least 100 Cas9-associated guide RNAs that are each complementary to a different, pre-defined, site in a genome. Kits for performing the method are also provided. In addition, other methods, compositions and kits for manipulating nucleic acids are also provided.

Abstract: A multi sectioned nut is operable to attach to a threaded fastener. The multi sectioned nut includes a plurality of multi sectioned threaded nut sections and a turn-lock formed on at least one end of the plurality of threaded nut sections. A cage is detachably coupled to the plurality of nut sections operable to spring open on a side opposite the cage to allow the threaded fastener to pass through. The turn-lock is inserted into a strut slot and rotated to removably attach to the strut slot. According to one embodiment, the multi sectioned nut may include at least two sections.

Abstract: A multiple-firing clip device includes a hollow shaft defining a lateral opening communicating with an environment and a distal shaft portion between the lateral opening and a distal end opening. A shuttle longitudinally moves on the shaft and comprises a shuttle body defining a lumen surrounding the shaft, a snare, and a snare-extender slide defining a snare track to form a snare travel path in which the snare is disposed from the body and through the track and a portion of the body. The slide moves along a given extent defining a slide distance and a distal end and movement of the slide to the distal end shortens the snare travel path to extend the snare portion through the lateral opening, through the distal shaft portion, and distally out from a distal side of the body longer than the given extent to secure a suture with the snare.

Abstract: A cloud computing system can be configured to generate data models. A model optimizer of the cloud computing system can provision computing resources of the cloud computing system with a data model. A dataset generator of the cloud computing system can generate a synthetic dataset for training the data model. The computing resources can train the data model using the synthetic dataset. The model optimizer can store the data model and metadata of the data model in a model storage. The cloud computing system can receive production data from a data source by a production instance of the cloud computing system using a common file system. The production data can be processed using the data model by the production instance. The computing resources, the dataset generator, and the model optimizer can be hosted by separate virtual computing instances of the cloud computing system.

Abstract: A cloud computing system can be configured to generate a synthetic data stream that tracks a reference data stream. A model optimizer of the cloud computing system can receive, from an interface of the cloud computing system, a synthetic data stream request indicating a reference data stream. A dataset generator of the cloud computing system can generate a synthetic data stream that tracks the reference data stream by repeatedly swapping data models of the reference data stream. One such repeat can include retrieving, by the dataset generator from a model storage, a current data model of the reference data stream and generating a new data model of the reference data stream. The model optimizer can store the new data model in the model storage. The dataset generator can generate a synthetic data stream using the current data model of the reference data stream.

Abstract: A method of transporting waxy crude hydrocarbon includes: providing a container having an internal chamber with at least one port for receiving flowable waxy crude, wherein the container is provided at a refinery location; filling the internal chamber of the container with a filling system for loading the waxy crude hydrocarbon into the container; allowing the waxy crude hydrocarbon to cool and solidify into a non-flowable state; transporting the container having the non-flowable waxy crude hydrocarbon with at least one transport vehicle, wherein the transporting is performed without actively heating the waxy crude hydrocarbon with an active heating system, wherein the transporting is along a transportation route having a beginning at the refinery location and an ending; heating the waxy crude hydrocarbon at the ending of the transportation route until flowable; and removing the flowable waxy crude hydrocarbon from the container with an emptying system.

Abstract: Disclosed is an evaluation device for determining a vehicle action, wherein the evaluation device is configured to supply an artificial neural network, which outputs the vehicle action, with data regarding a vehicle environment. The artificial neural network predicts an accident situation on the basis of these data, to evaluate a damage function for personal injury and/or material damages, calculated on the basis of simulated vehicle actions, and to determine the vehicle action for which the damage function delivers the lowest results in this accident situation. Also disclosed is a computer program product for obtaining a damage function based on personal injury and/or material damages, a method for training an artificial neural network that minimizes a damage function through reinforcement learning, a system for controlling a vehicle for making situation-dependent decisions, and a driver assistance system that has a system according to the disclosure, or an artificial neural network.

Abstract: In one example, an apparatus includes a first switch array including a first plurality of switches. A first resistor array includes a first plurality of resistor pairs, where each resistor pair in the first plurality of resistors is coupled to one switch of the first plurality of switches. The apparatus also includes a second switch array including a second plurality of switches. A second resistor array includes a second plurality of resistor pairs, where each resistor pair in the second plurality of resistors is coupled to one switch of the second plurality of switches. The apparatus further includes a plurality of output nodes configured to transmit an analog voltage, where each output node of the plurality of output nodes is connected to one resistor pair of the first resistor array and one resistor pair of the second resistor array.

Abstract: A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion can have an actuation mechanism with a motor. The rotatable drive shaft can have a proximal end portion and a distal end portion. The proximal end portion of the rotatable drive shaft can be coupled to the motor, and the distal end portion of the rotatable drive shaft can be configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism can be configured to control and monitor expansion of the prosthetic heart valve and to control and monitor torque of the motor.

Abstract: The present invention relates to an aqueous agrochemical spray solution containing an agrochemical active and a surfactant. The spray solution comprises a dispersed phase comprising dispersed particles which have an average particle size between 1 to 100 microns and the concentration of said dispersed particles is from about 0.001 to 5 wt %. The aqueous agrochemical spray solution is capable of reducing the volume of the fine droplets in mist whose size is less than 150 microns during spraying by at least 20% compared to the same aqueous spray solution without the presence of the surfactant. The present invention also relates to a method of reducing the spray drift of an aqueous agrochemical spray solution upon spraying with a spraying apparatus. The method includes adding the surfactant to the aqueous agrochemical spray solution in an amount effective to form the dispersed phase.

Abstract: A magnetic bracket includes a base and at least two posts at opposite ends of the base. The posts bend upwards from the base such that at least two clips are operable to attach at the posts at opposite ends of the base. The posts have a notch between the base and ends of the posts to permit the clips to hook onto the posts. The magnetic bracket may be clipped into a vehicle chassis by removably inserting the clips into a slot of the vehicle chassis. A body panel such as a headliner having a magnetic fastener attached to the body panel may then be magnetically self-aligned and removably attached to the base having a magnetic portion. The magnetic fastener is operable to be removably attached to the magnetic portion. The magnetic bracket is attached to a non-magnetic part of a vehicle chassis.

Abstract: A device for manufacturing inner trim elements which are formed by a rigid carrier and a cover layer, between which elements a polymer foam layer is arranged. The carrier is fixable on a first molding tool element, and the cover layer is fixable between the outer edge of the first molding tool element and the outer edge of a second molding tool element. In the molding tool, a cavity is formed between the carrier and the cover layer, wherein a foamable polymer is introducible into the cavity via at least one through-hole which is formed in the carrier and the first molding tool element. The distance between the first and the second molding tool element is enlargeable during the foaming process. At least one through-hole for an escape of air and reactively formed gases out of the cavity is formed in the carrier and in the first molding tool element.

Abstract: An evaluation device for obtaining a segmentation of an environment from a radar recording of the environment, that has an input interface configured to obtain initial training data, where the initial training data comprise radar data of the radar recording and initial characteristics of objects located in the environment recorded with a radar sensor that generates the radar recordings, and where the evaluation device is configured to forward propagate an artificial neural network with the initial training data to obtain second characteristics of the objects determined with the artificial neural network in the forward propagation, and to obtain weighting factors for neural connections of the artificial neural network through backward propagation of the artificial neural network with the differences between the second characteristics and the initial characteristics, in order to obtain the segmentation of the environment through renewed forward propagation with these radar data.

Abstract: A fire suppression and annunciation system using a flexible conduit and a wire rope is provided. The wire rope may be connected to a knob assembly at a universal pull station and to a release mechanism of the fire suppression system. An operator may pull a handle of the knob assembly at the universal pull station, thereby activating the release mechanism to release fire suppression agent. A flexible conduit may house the wire rope along at least a part of the connection from the universal pull station to the release mechanism. A material on the liner of the flexible conduit and/or on the wire rope may be used to reduce the coefficient of friction of wire rope in the flexible conduit. The fire suppression system may further include a pulley block system connected to the universal pull station. The pulley block system may comprise bearings, and may lower the force necessary to activate the release mechanism.

Abstract: An external LAA exclusion clip comprises a clipping assembly comprising first and second opposing clip struts each of the clip struts having a tissue-contacting surface and first and second bias surfaces, a bias assembly connecting the first clip strut to the second clip strut to align the first and second clip struts in a strut plane passing through the tissue-contacting surface. The bias assembly comprises at least one first bias spring connected to the first bias surface of the first clip strut and to the first bias surface of the second clip strut and at least one second bias spring connected to the second bias surface of the first clip strut and the second bias surface of the second clip strut. The first bias spring and the second bias spring are configured to permit movement of the first and second clip struts in the strut plane.

Abstract: The present invention relates to an aqueous agrochemical spray solution containing an agrochemical active and a surfactant. The spray solution comprises a dispersed phase comprising dispersed particles which have an average particle size between 1 to 100 microns and the concentration of said dispersed particles is from about 0.001 to 5 wt %. The aqueous agrochemical spray solution is capable of reducing the volume of the fine droplets in mist whose size is less than 150 microns during spraying by at least 20% compared to the same aqueous spray solution without the presence of the surfactant. The present invention also relates to a method of reducing the spray drift of an aqueous agrochemical spray solution upon spraying with a spraying apparatus. The method includes adding the surfactant to the aqueous agrochemical spray solution in an amount effective to form the dispersed phase.