Patents by Inventor Michael A. Whitt

Michael A. Whitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170232253
    Abstract: Disclosed are methods and devices utilizing bioelectrodynamics for the therapeutic treatment of disorders in a subject in need thereof with an electric field or electromagnetic field therapy. The methods and devices provide an inhibitory effect on growth of cancer cells that are exposed to an electromagnetic field generated by a CETS unit. Cancer cells may arrest proliferation and enter apoptosis by activation of the unfolded protein response (UPR), TNF/TRAIL, and p53 oncogene activation. The methods and devices may be used to enhance wound healing with exposure to an electromagnetic field generated by a CETS unit. Noncancerous cells may show a significant increase in cell migration with no activation of apoptosis pathways.
    Type: Application
    Filed: February 16, 2016
    Publication date: August 17, 2017
    Inventors: Marcy C. Purnell, Michael A. Whitt
  • Patent number: 7994295
    Abstract: Recombinant viruses, isolated nucleic acids and methods of generating same encoding for a Rhabdoviral G stem polypeptide are disclosed. Methods, compounds and compositions for target cell fusion potentiation mediated by Rhabdoviral G stem polypeptides, and applications of same are provided.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: August 9, 2011
    Assignee: The University of Tennessee Research Corporation
    Inventors: Michael A. Whitt, Clinton S. Robison
  • Publication number: 20100167377
    Abstract: Recombinant viruses, isolated nucleic acids and methods of generating same encoding for a Rhabdoviral G stem polypeptide are disclosed. Methods, compounds and compositions for target cell fusion potentiation mediated by Rhabdoviral G stem polypeptides, and applications of same are provided.
    Type: Application
    Filed: December 23, 2002
    Publication date: July 1, 2010
    Inventors: Michael A. Whitt, Clinton S. Robison
  • Publication number: 20030138457
    Abstract: This invention relates to a composition comprising a recombinant or genetically engineered Rhabdovirus that expresses a Fusion Protein, such as the F protein of the Paramyxovirus SV5 strain. This recombinant Rhabdovirus may express other non-Rhabdovirus attachment proteins and/or an enhancer protein. The invention also relates to methods of making recombinant Rhabdoviruses which express an F Protein. These recombinant compositions can be used for purposes of research, as well as for diagnostic and therapeutic compositions for treatment of diseases.
    Type: Application
    Filed: October 23, 2002
    Publication date: July 24, 2003
    Inventors: Michael A. Whitt, Clinton S. Robison
  • Patent number: 6497873
    Abstract: This invention relates to a composition comprising a recombinant or genetically engineered Rhabdovirus that expresses a Fusion Protein, such as the F protein of the Paramyxovirus SV5 strain. This recombinant Rhabdovirus may express other non-Rhabdovirus attachment proteins and/or an enhancer protein. The invention also relates to methods of making recombinant Rhabdoviruses which express an F Protein. These recombinant compositions can be used for purposes of research, as well as for diagnostic and therapeutic compositions for treatment of diseases.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: December 24, 2002
    Assignee: The University of Tennessee Research Corporation
    Inventors: Michael A. Whitt, Clinton S. Robison