Abstract: The present invention provides compounds of Formula I, and the tautomers thereof, and the pharmaceutically acceptable salts of the compounds and tautomers, wherein the compounds have the structure wherein the variables R1, R2, R3, R4 and x are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, and the variables R1 and R2 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: A single-piece multi-fiber ferrule interconnect assembly including a ferrule body having a main surface, a front frame, and a rear opening, wherein the front frame includes a front face and a back face; a plurality of lenses arranged to form a lens array, wherein the lenses are fabricated within the front frame and recessed from the front face; a plurality of grooves on the main surface for receiving a plurality of optical fibers, the grooves extending from the back face toward the rear opening, wherein each groove comprises a terminus located at the focal point of a corresponding lens on the front frame; a well located on the main surface along the back face of the front frame, wherein inside edges of the well are curved and wherein the well is capable of accommodating an epoxy; and a plurality of guide pin passageways on the ferrule body each having a pin aperture for receiving alignment pins from a complementary ferrule body, wherein the pin aperture and the alignment pin from the complementary ferrule bod

Abstract: The present invention provides compounds of Formula I, and the tautomers thereof, and the pharmaceutically acceptable salts of the compounds and tautomers, wherein the compounds have the structure wherein the variables R1, R2, R3, R4 and x are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: Systems and methods for syndicating advertising content are described. In one embodiment, a method of syndicating relevant user activities includes obtaining a first advertising bid from a first advertising site, obtaining a second advertising bid from a second advertising site, recording user activities with a first participating site, classifying the recorded user activities describing at least one category associated with the recorded user activity, determining an auction strategy based on the first advertising bid, the second advertising bid, the first advertising site, and the second advertising site, where the auction strategy selects at least one winning advertising site, generating an ad unit ad unit including metadata describing the recorded user activity and the at least one winning advertising site, and syndicating the generated ad unit to at least one participating site within an advertisement network.

Abstract: Absorbable and non-absorbable cyanoacrylate tissue adhesive/sealant formulations include at least one multipurpose carboxylic, acid-bearing C-succinylated polymeric rheology modifier capable of increasing the viscosity of the liquid formulation, while controlling the anionic polymerization of the cyanoacrylate monomers and increasing the compliance of the cured solid adhesive.

Abstract: The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, and the variables R1 and R2 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: Methods for tracking customer spending: the methods may comprise receiving from the customer a first threshold amount and a period length; receiving a transaction indication for each debit transaction made by the customer during a first period; and alerting the customer if the sum of the amounts of debit transactions during the first period exceeds the first threshold amount. The methods may also comprise receiving a transaction indication for each debit transaction made by the customer during a second period; and alerting the customer if the sum of the amounts of debit transactions during the second period exceeds a second threshold amount.

Abstract: The present invention provides compounds of Formula I, and the tautomers thereof, and the pharmaceutically acceptable salts of the compounds and tautomers, wherein the compounds have the structure wherein the variables R1, R2, R3, R4 and x are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: A tool for aligning fibers in a ferrule, the tool comprising a body portion having a register surface; and at least one alignment member at a certain angle from the register surface, the alignment member configured to cooperate with a corresponding alignment member of a ferrule, wherein the register surface is non-planar.

Abstract: A calling type identification system selects a calling type. The system selects NPA-NXX telephone number blocks for the calling type based on NPA-NXX block categories related to the calling type. The system develops number data for the selected NPA-NXX telephone number blocks. The system receives a telephone number for a call. The system processes the telephone number and the number data to identify and indicate if the telephone call is of the selected calling type.

Abstract: A portable device for attaching a connector to an optical fiber, the optical fiber having an end, the device comprising means for receiving the optical fiber at the end of the optical fiber; and a connector station for autonomously attaching the connector to the optical fiber.

Abstract: Systems and methods for automatically generating targeting information for presentation of an offer in accordance with embodiments of the invention are disclosed. One embodiment includes indexing member profiles within one or more social networks for affinity to keywords using a targeting system that retrieves data concerning member profiles and activities from servers within an online social network, identifying member profiles that have affinity for at least one offer keyword using the targeting system and the index, identifying additional keywords for which the identified member profiles have affinity using the targeting system and the index, determining a set of keywords that target a desired audience based upon the identified additional keywords using the targeting server, and targeting presentation of advertisements for the specific offer to members of an online social network using the online social network and the targeting keywords determined by the targeting server.

Abstract: Computer implemented methods of tracking customer spending and income are provided. The methods may comprise aggregating spending transactions by estimating income to a customer during a first time period. The methods may also comprise displaying a user interface to the customer. The user interface may comprise a first bar indicating customer income and a second bar indicating customer spending.

Abstract: An interactive computer system and method for recruiting potential employee candidates. A user interactive Graphical User Interface (GUI) is provided on a computering device connected to a network for tracking and storing an employee candidate lifecycle with a potential employer. The GUI is preferably configured and operational to provide interactive promotional materials regarding an employment opportunity with a potential employer and establish a first video conference between the candidate and at least one representative of the potential employer.