Abstract: An implantation tool to implant a paranasal sinus fluid access implant device to fluidly connect the lacrimal apparatus in the orbit with a paranasal sinus has a securement mechanism reconfigurable from a securement configuration to secure the implant device to a mounting portion of a carrier member to a released configuration to release the implant device from the carrier member, and with a release mechanism disposed at least partially in an interior working space housed within the implantation tool. An implantation method with an approach through the palpebral fissure advances the implant device through a surgical route mostly under tension.

Abstract: Systems, methods, and apparatuses for managing and controlling movable barrier operator systems are described herein. A method for controlling a movable barrier operator system comprises receiving a credential associated with a first user account from a first user device, storing the credential in a memory of the movable barrier operator system, communicating the credential and an identifier of the movable barrier operator system to a remote computer to register the movable barrier operator system with the remote computer, and configuring the movable barrier operator system to change a state of a movable barrier in response to the movable barrier operator system receiving a state change request from a second user device associated with a second user account, the state change request from the second user device including the credential or a derivative of the credential received from the first user device.

Abstract: A method for calibrating a magnetometer of a device is provided. The method includes collecting, with a portable calibration device having a magnetometer, magnetic field measurements in a spatial region about a mounting location where the device is to be installed for operation, estimating magnetometer compensation parameters to correct for magnetic field distortion at the mounting location based on the magnetic field measurements collected by the portable calibration device, and configuring the device installed at the mounting location based on the magnetometer compensation parameters.

Abstract: An apparatus and a method use permeate to flush a reverse osmosis filter membrane in the same flow direction as when fluid is being filtered through the membrane. The apparatus includes a housing having a membrane positioned therein. The membrane has an interior surface and an exterior surface. The housing has an inlet port located outward of the exterior surface of the membrane and first and second outlet ports. The first outlet port is located outward of the exterior surface of the membrane and the second outlet port is located inward of the interior surface of the membrane. A first pump is used to route pressurized, untreated fluid from a fluid source through the membrane to produce permeate. A second pump is used to route permeate to a desired function while also routing some permeate at low pressure to the housing to flush the membrane.

Abstract: Described herein are methods for the expression and purification of Cas13a and methods for detecting target RNA using Cas13a.

Abstract: Described herein are methods for the expression and purification of Cas13a and methods for detecting target RNA using Cas13a.

Abstract: Methods and systems are disclosed that monitor the carbon and hydrogen production of a pyrolysis reactor system and adjust one or more inputs to the reactor system to improve performance when one or both of the monitored carbon and hydrogen production falls outside of a target performance specification. In particular, the ratio of fuel to oxidant (“fuel/oxidant ratio”) supplied to a combustion chamber of the reactor system is adjusted to below a fuel/oxidant equivalence ratio range, defined as 0.9-1.1, when both carbon and hydrogen production falls below a target carbon and hydrogen specification, and adjusted above the fuel/oxidant equivalence ratio range when only the carbon production falls below a target carbon specification. The target specification can include a number of parameters including production rate, morphology (of carbon), and operating temperature.

Abstract: The present invention provides, in part, compounds of Formula I: or an N-oxide thereof, or a pharmaceutically acceptable salt of the compound or the N-oxide, wherein: R1, R2, L, A, and E are as described herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds, N-oxides, or salts, and their uses for treating M4-mediated (or M4-associated) disorders including, e.g., Alzheimer's Disease, schizophrenia (e.g., its cognitive and negative symptoms), pain, addiction, and a sleep disorder.

Abstract: The present disclosure relates to a telecommunications connector. The connector includes at least one connector portion including a front housing portion coupled to a rear housing portion. The front housing portion defines a front end and a rear end, the front housing portion including a ferrule terminating a cable fixed to the at least one connector portion, the front housing portion further including a latch that is configured to contact a fiber optic adapter for locking the connector to the fiber optic adapter when the connector is inserted into the fiber optic adapter, wherein the latch is movable about a connection location on the front housing portion. The latch defines a permanently attached rear extension that extends rearward past the rear end of the front housing portion, the rear extension configured to be contacted for moving the latch for freeing the connector from the fiber optic adapter.

Abstract: A method for virtual computing instance remediation is provided. Some embodiments include retrieving a first backup of a virtual machine from storage, the first backup comprising configuration information and data of the virtual machine, the configuration information comprising network connectivity information in a first software defined data center (SDDC) running on a first set of host machines. Some embodiments include configuring a second SDDC running on a second set of host machines based on the configuration information, where the second SDDC is network isolated from the first SDDC and powering on the virtual machine from the first backup in the second SDDC. Some embodiments include sending, from the virtual machine to a security platform, behavior information of the virtual machine running in the second SDDC and determining, based on the behavior information, whether the virtual machine running in the second SDDC is infected with malware.

Abstract: An electrical device such as, for example, a battery-powered electrical switch is disclosed. The battery-powered wireless switch includes one or more mechanisms arranged and configured to provide simplified access for servicing (e.g., replacing) the batteries located within the wireless switch. In one embodiment, the wireless switch is arranged and configured so that the batteries may be accessed by reconfiguring the wireless switch from a first closed position to a second opened position to access the batteries. Thus arranged, removal of the wireless switch from a wall-box or a surface of a wall is not required, the user may only need to remove the wall-plate in order to reconfigure the wireless switch. In one embodiment, at least a portion of the wireless switch is pivoted from the first position to the second position to provide access to the batteries.

Abstract: An implantable medical device, including a magnet and a body encompassing the magnet, wherein the implantable medical device includes structural components in the body configured to move away from one another upon initial rotation of the magnet relative to the body when the magnet is subjected to an externally generated magnetic field, thereby limiting rotation of the magnet beyond the initial rotation.

Abstract: Heat dissipation system, a power converter using such a heat dissipation system, and an associated method of thermal management of the power converter are disclosed. The heat dissipation system includes a condenser, a first cooling loop, and a second cooling loop. The first cooling loop is coupled to the condenser and includes a first two-phase heat transfer device. The second cooling loop is coupled to the condenser and includes a second two-phase heat transfer device. The condenser is disposed above the first and second two-phase heat transfer devices.

Abstract: Embodiments of the disclosure are drawn to apparatuses and methods for a rotating optical reflector. Optical systems may have a limited field of view, and so in order to expand the area that the optical system collects data from, the field of view of the optical system may be scanned across a target area. The present disclosure is directed to a rotating optical reflector, which includes a transmissive layer which refracts light onto a reflective layer, which has a normal which is not parallel to the axis about which the optical reflector is rotated. The optical reflector may be both statically and dynamically balanced, which may allow an increased size of the optical reflector, which in turn may increase the aperture of an optical system (e.g., a lidar system) using the rotating optical reflector.

Abstract: A circuit breaker includes a line phase terminal, a load phase terminal, a line neutral terminal, a conductive path formed between the line phase terminal and the load phase terminal, the conductive path having an open configuration and closed configuration, a sensor, a linkage configured to move the conductive path between the open configuration and the closed configuration, a rocker selectively engageable with the linkage, the rocker configured to move the linkage between an open position and a closed position, and an arm selectively engageable with the rocker, the arm to prevent the conductive path from moving to the closed configuration unless the circuit breaker passes a self-test when movement of the rocker is detected. A trip operation of the circuit breaker includes a time delay based upon an amount of current on the conductive path detected by the sensor.

Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g.

Abstract: A collapsible system for water body fishing and game hunting comprises a folding frame with an attached platform, all made from galvanized aluminum. The folding frame includes a front left and front right vertical pipe, and a left bent angle and right bent angle pipe, with the left bent angle and right bent angle pipe joined at a vertex with an attached towing hitch. The folding frame also uses horizontal and diagonal braces attachable and connecting the front left and front right vertical pipe to the left bent angle and right bent angle pipe with a lower left horizontal brace and lower right horizontal brace attached to a lower rear horizontal brace or lower front horizontal brace so as to pivot.

Abstract: A circuit breaker is configured to be remotely caused to enter ON and OFF states. A lever arm is pivotably coupled to a main contact spring. A contact is supported at the distal end portion of the lever arm. Pivoting of the lever arm to bring the contact into contact with another contact on the housing causes the circuit breaker to enter the ON state. Pivoting of the lever arm to separate the contacts causes the circuit breaker to enter the OFF state. A latching solenoid includes a plunger coupled to the lever arm. The latching solenoid moves the plunger between a retracted configuration and an extended configuration. When in the extended position, the lever arm is pivoted to separate the contacts to cause the circuit breaker to enter the OFF state.

Abstract: A double network hydrogel consists of a first network and a second network, where the first network is, or includes, a first polymer that is formed, at least in part, of —CH2—CH(OH)— units, and the second network is, or includes, a second polymer that is formed, at least in part, of carboxyl (COOH)-containing units or salts thereof, sulfonyl (SO3H)-containing units or salts thereof, and at least one of hydroxyl (OH)-containing units or amino (NH2)-containing units, where the hydrogel may be used as a cartilage replacement.

Abstract: Content is organized for brands by selecting a plurality of brand templates. After each selection, a set of properties is generated by applying a portion of settings of the respective brand template, with the remaining settings being overridden with settings for a channel communicating one of a plurality of presentations to a node of a network involved in the communication. The plurality of presentations may include different renditions of the same content. The properties may include sections configured for different focus areas and/or types of content associated with at tags to enable brand-level-targeting. Filters may be identified in the properties. Based on each of the identifications, a property from among the generated sets of properties may be selected based on comparisons with the associated tags.