Abstract: Systems and methods for providing, sharing, storing and playing widgets and associated media content on a personal audiovisual device, such as a digital photo frame, are described. In one implementation, widgets may be selected by a user for rendering based on capabilities of a user's device, with the widgets then provided to the device for playback. Digital content such as audio files, images, and/or video may be rendered in conjunction with playback of the widget. Widgets may be shared between users so as to facilitate sharing of media content.

Abstract: The present invention is flow rate meters which are able to accurately measure the volumetric rate of flow of a liquid through a conduit without requiring foreknowledge of the physicochemical characteristics of the liquid, e.g., for the purpose of calibration of the thermal mass flow rate. One application of the flow meters of the invention is to incorporate them in a system for measuring the flow rate of urine excreted by a catheterized patient. The invention also provides methods for using the flow rate meters.

Abstract: A book binding machine includes a book block transport system and a plurality of clamps for clamping stacks of leaves. The clamps are disposed at a distance from each other and are guided in guide tracks of a machine frame. The book block transport system includes a clamp, which is also referred to as a lubrication clamp, having a device for lubricating the guide track. An applicator is assigned to each track roller of the clamp, and the lubricant is transferred to the track rollers through the use of a respective applicator such as a brush. The track rollers transfer the lubricant to contact surfaces of the guide track. A lubrication clamp for a book block transport system in a book binding machine, is also provided.

Abstract: Pharmaceutical liquid formulation of an antibody against human OX40L, a process for the preparation and uses of the formulation.

Abstract: A book binding machine includes a book block transport system and a plurality of clamps for clamping stacks of leaves. The clamps are disposed at a distance from each other and are guided in guide tracks of a machine frame. The book block transport system includes a clamp, which is also referred to as a lubrication clamp, having a device for lubricating the guide track. An applicator is assigned to each track roller of the clamp, and the lubricant is transferred to the track rollers through the use of a respective applicator such as a brush. The track rollers transfer the lubricant to contact surfaces of the guide track. A lubrication clamp for a book block transport system in a book binding machine, is also provided.

Abstract: In an example embodiment, a mobile wireless device, such as a mobile telephone, is employed to configure a second wireless device such as an access point. The mobile wireless device determines its location and a regulatory domain corresponding to the location. The mobile wireless device configures the second wireless device to operate in the regulatory domain.

Abstract: Systems and methods for location, motion, and contact detection and tracking in a portable networked device are disclosed. A portable device may include a motion detection unit including an accelerometer for detecting accelerations in one or more axes. Signals associated with the detected motion are processed to generate estimates of device acceleration, velocity, and relative and absolute locations. Additional processing may be performed to detect user gestures or other user input relevant to portable device control. Particular motion or vibrational characteristics may be also be detected and used by other processes in the portable device.

Abstract: This invention relates to a pharmaceutical formulation of an antibody against Epidermal Growth Factor Receptor (EGFR), a process for the preparation and uses of the formulation.

Abstract: A method for treating organophosphorous poisoning (OP) comprising administering to a mammal at risk for OP poisoning an OP poisoning-inhibiting amount of galantamine.

Abstract: Systems and methods for location, motion, and contact detection and tracking in a portable networked device are disclosed. A portable device may include a motion detection unit including an accelerometer for detecting accelerations in one or more axes. Signals associated with the detected motion are processed to generate estimates of device acceleration, velocity, and relative and absolute locations. Additional processing may be performed to detect user gestures or other user input relevant to portable device control. Particular motion or vibrational characteristics may be also be detected and used by other processes in the portable device.

Abstract: The present invention relates to a highly concentrated, stable pharmaceutical formulation of a pharmaceutically active anti-CD20 antibody, such as e.g. Rituximab, Ocrelizumab, or HuMab<CD20>, or a mixture of such antibody molecules for subcutaneous injection. In particular, the present invention relates to formulations comprising, in addition to a suitable amount of the anti-CD20 antibody, an effective amount of at least one hyaluronidase enzyme as a combined formulation or for use in form of a co-formulation. The said formulations comprise additionally at least one buffering agent, such as e.g. a histidine buffer, a stabilizer or a mixture of two or more stabilizers (e.g. a saccharide, such as e.g. ?,?-trehalose dihydrate or sucrose, and optionally methionine as a second stabilizer), a nonionic surfactant and an effective amount of at least one hyaluronidase enzyme. Methods for preparing such formulations and their uses thereof are also provided.

Abstract: Systems and methods for providing, sharing, storing and playing widgets and associated media content on a personal audiovisual device, such as a digital photo frame, are described. In one implementation, widgets may be selected by a user for rendering based on capabilities of a user's device, with the widgets then provided to the device for playback. Digital content such as audio files, images, and/or video may be rendered in conjunction with playback of the widget. Widgets may be shared between users so as to facilitate sharing of media content.

Abstract: The present invention relates to a highly concentrated, stable pharmaceutical formulation of a pharmaceutically active anti-HER2 antibody, such as e.g. Trastuzumab (HERCEPTIN™), Pertuzumab or T-DM1, or a mixture of such antibody molecules for subcutaneous injection. In particular, the present invention relates to formulations comprising, in addition to a suitable amount of the anti-HER2 antibody, an effective amount of at least one hyaluronidase enzyme as a combined formulation or for use in form of a co-formulation. The formulations comprise additionally at least one buffering agent, such as e.g. a histidine buffer, a stabilizer or a mixture of two or more stabilizers (e.g. a saccharide, such as e.g. ?,?-trehalose dihydrate or sucrose, and optionally methionine as a second stabilizer), a nonionic surfactant and an effective amount of at least one hyaluronidase enzyme. Methods for preparing such formulations and their uses thereof are also provided.

Abstract: A method of treating organophosphorous (OP) poisoning comprising administering to a mammal at risk for OP poisoning an OP poisoning-inhibiting amount of galantamine.

Abstract: The present invention relates to a method for the highly sensitive Immuno-PCR detection of an analyte in a sample comprising the use of a nucleic acids containing sample dilution buffer for diluting the sample as well as methods for the preparation of the sample dilution buffer and the use thereof.

Abstract: A book binding machine includes a collating machine, a perfect binder and a transfer device disposed between the collating machine and the perfect binder. The collating machine and the perfect binder are actuated by a common control device. In each case, one transport segment is assigned to a respective book block clamp by the control device. The control device also has a program which, if a defective or missing book block clamp is detected, actuates the collating machine in such a way that no book block is collated for that book block clamp. A method for operating a book binding machine is also provided.

Abstract: Systems and methods for location, motion, and contact detection and tracking in a portable networked device are disclosed. A portable device may include a motion detection unit including an accelerometer for detecting accelerations in one or more axes. Signals associated with the detected motion are processed to generate estimates of device acceleration, velocity, and relative and absolute locations. Additional processing may be performed to detect user gestures or other user input relevant to portable device control. Particular motion or vibrational characteristics may be also be detected and used by other processes in the portable device.

Abstract: The present invention relates to novel conjugate complexes for immunoassays as well as kits comprising these conjugate complexes, methods of producing these complexes, and methods of detecting an analyte by use of these complexes. The conjugate complexes of the invention comprise one or more non-nucleic acid receptors capable of specifically binding an analyte, one or more nucleic acid markers comprising a predetermined nucleotide sequence, one or more first linker molecules capable of specifically binding the non-nucleic acid receptor and the nucleic acid marker, and one or more second linker molecules capable of specifically binding the first linker molecules.

Abstract: Pharmaceutical formulations of an antibody against OX40L and processes for making the same.

Abstract: A method for preparing a protein or peptide powder is provided that includes spray drying a solution including more than, e.g., about 50 mg/mL of a protein or peptide (e.g., an antibody or antigen binding portion thereof), and at least one excipient. Also provided are stable powdered compositions including a protein and an excipient having less than, e.g., about 6% residual moisture.