Patents by Inventor Michael AMATANGELO

Michael AMATANGELO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CYTOKINE-RELATED ADVERSE EVENTS
    Publication number: 20230172923
    Abstract: The disclosure relates to agents for use in the treatment or prevention of a cytokine-related adverse event or disease, such as cytokine release syndrome (CRS).
    Type: Application
    Filed: April 29, 2021
    Publication date: June 8, 2023
    Inventors: Danny Vijey JEYARAJU, Michael AMATANGELO, Ross LA MOTTE-MOHS, William PIERCEALL, Anjan G. THAKURTA
  • IDH1 INHIBITORS FOR THE TREATMENT OF HAEMATOLOGICAL MALIGNANCIES AND SOLID TUMORS
    Publication number: 20200261434
    Abstract: Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
    Type: Application
    Filed: May 7, 2020
    Publication date: August 20, 2020
    Inventors: Sung Eun Choe, Bin Wu, Michael Amatangelo, Xiaolan Hu, Anjan Thakurta
  • IDH1 INHIBITORS FOR THE TREATMENT OF HAEMATOLOGICAL MALGNANCIES AND SOLID TUMORS
    Publication number: 20190046512
    Abstract: Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
    Type: Application
    Filed: December 2, 2016
    Publication date: February 14, 2019
    Applicants: Agios Pharmaceuticals, Inc., Celgene Corporation, Celgene Corporation
    Inventors: Michael Amatangelo, Xiaolan Hu, Anjan Thakurta, Sung Eun Choe, Bin Wu
  • Methods of treatment of malignancies
    Patent number: 10137130
    Abstract: Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: November 27, 2018
    Assignees: Celgene Corporation, Agios Pharmaceuticals, Inc.
    Inventors: Michael Amatangelo, Xiaolan Hu, Anjan Thakurta, Sung Eun Choe, Bin Wu
  • METHODS OF TREATMENT OF MALIGNANCIES
    Publication number: 20180042930
    Abstract: Provided are methods and compositions for treating a malignancy in patients carrying an IDH2 mutation.
    Type: Application
    Filed: August 2, 2017
    Publication date: February 15, 2018
    Inventors: Michael Amatangelo, Xiaolan Hu, Anjan Thakurta
  • CEREBLON ISOFORMS AND THEIR USE AS BIOMARKERS FOR THERAPEUTIC TREATMENT
    Publication number: 20170362660
    Abstract: Provided herein are cereblon isoforms and methods of their use as biomarkers for treating a disease, disorder, or condition with a treatment compound, e.g., thalidomide, lenalidomide, pomalidomide, 3-(5-amino-2-methyl-4-oxoquinazolin-3 (4H)-yl)-piperidine-2,6-dione, or (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione.
    Type: Application
    Filed: January 24, 2017
    Publication date: December 21, 2017
    Inventors: Anjan THAKURTA, Anita GANDHI, Michelle F. WALDMAN, Rajesh CHOPRA, Michael AMATANGELO, Chad BJORKLUND
  • METHODS OF TREATMENT OF MALIGNANCIES
    Publication number: 20170246174
    Abstract: Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
    Type: Application
    Filed: December 2, 2016
    Publication date: August 31, 2017
    Inventors: Michael Amatangelo, Xiaolan Hu, Anjan Thakurta, Sung Eun Choe, Bin Wu
  • Cereblon isoforms and their use as biomarkers for therapeutic treatment
    Patent number: 9587281
    Abstract: Provided herein are cereblon isoforms and methods of their use as biomarkers for treating a disease, disorder, or condition with a treatment compound, e.g., thalidomide, lenalidomide, pomalidomide, 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)-piperidine-2,6-dione, or (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: March 7, 2017
    Assignee: CELGENE CORPORATION
    Inventors: Anjan Thakurta, Anita Gandhi, Michelle F. Waldman, Rajesh Chopra, Michael Amatangelo, Chad Bjorklund
  • CEREBLON ISOFORMS AND THEIR USE AS BIOMARKERS FOR THERAPEUTIC TREATMENT
    Publication number: 20150152511
    Abstract: Provided herein are cereblon isoforms and methods of their use as biomarkers for treating a disease, disorder, or condition with a treatment compound, e.g., thalidomide, lenalidomide, pomalidomide, 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)-piperidine-2,6-dione, or (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione.
    Type: Application
    Filed: February 12, 2015
    Publication date: June 4, 2015
    Inventors: Anjan THAKURTA, Anita GANDHI, Michelle F. WALDMAN, Rajesh CHOPRA, Michael AMATANGELO, Chad BJORKLUND