Abstract: A refuse vehicle includes a vehicle body on a chassis having a frame, an internal combustion engine (ICE), and a transmission coupling the ICE with a plurality of tractive elements. The vehicle body includes an electrically powered body system and a hydraulically powered body system. A first power module is coupled with the ICE and is configured to provide rotary power to a hydraulic pump that is configured to provide hydraulic power to the hydraulically powered body system. A second power module is coupled with the transmission and configured to rotationally couple and decouple an electrical generator with the transmission. The generator is configured to charge at least one battery when rotationally coupled with the transmission. The battery is configured to provide electrical power to the electrically powered body system.

Abstract: A refuse collection vehicle includes a wheeled chassis, a battery pack, a refuse collection body, and a DC-DC converter. The wheeled chassis has an electric propulsion motor connected to a road wheel of the chassis. The battery pack has multiple battery cells and provides electrical power to the propulsion motor. The refuse collection body is carried by the chassis and defines a refuse storage compartment. The refuse collection body includes a refuse packer driven by an electric packer motor. The refuse collection body also includes a powered tailgate driven by an electric tailgate motor. The DC-DC converter is connected to the battery pack and provides electrical power to the electric packer motor and to the electric tailgate motor at one or more DC voltages different than a voltage provided by the battery pack to the DC-DC converter.

Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

Abstract: The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

Abstract: The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The invention allows the generation of libraries which can be screened for e.g. therapeutic activity.

Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The invention allows the generation of libraries which can be screened for e.g. therapeutic activity.

Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.

Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.

Abstract: The present invention relates to a method for synthesizing templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.

Abstract: The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

Abstract: An unloading tool and methods of manipulating a load condition of a muzzle loading firearm. The unloading tool includes a tube having a breech end and a distal end. The unloading tool may have threads at the breech end of the tube for releasably engaging a breech of a firearm so as to facilitate the removal and reloading of powder with respect to the breech of the firearm.

Abstract: The unloading tool of the present invention includes a tube having a breech end and a distal end. The unloading tool may have threads at the breech end of the tube for releasably engaging a breech of a firearm so as to facilitate the removal and reloading of powder with respect to the breech. The present invention further encompasses a method for unloading powder from the breech of firearm including the steps of securing a breech end of a tubular unloading tool to a breech of the firearm and tilting the firearm to remove powder from the breech and into the unloading tool.

Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, solvates or prodrugs thereof, that bind to Inhibitor of Apoptosis Proteins (IAPs). The compounds of the invention may be used as diagnostic and therapeutic agents in the treatment of proliferative diseases, such as cancer, for promoting apoptosis in proliferating cells, and for sensitizing cells to inducers of apoptosis. The present invention furthermore provides a polymeric compound of formulas (VI) or (VII), comprising either at least two monomeric units of compounds of formula (I), or at least one monomeric unit of a compound of formula (I) and an entity E. The present invention further relates to pharmaceutical compositions comprising said compounds of formulas (I), (VI), and (VII) and the use of said compounds in medicine.

Abstract: The unloading tool of the present invention includes a tube having a breech end and a distal end. The unloading tool may have threads at the breech end of the tube for releasably engaging a breech of a firearm so as to facilitate the removal and reloading of powder with respect to the breech. The present invention further encompasses a method for unloading powder from the breech of firearm including the steps of securing a breech end of a tubular unloading tool to a breech of the firearm and tilting the firearm to remove powder from the breech and into the unloading tool.