Abstract: Sets of genetic markers for specific tumor classes are described, as well as methods of identifying a biological sample based on these markers. Also described are diagnostic, prognostic, and therapeutic screening uses for these markers, as well as oligonucleotide arrays comprising these markers.

Abstract: A search query may be run against a plurality of container registers encapsulated and logically defined in a plurality of containers to identify one or more container registers responsive to the search query. Thereafter, a list characterizing the identified containers may be provided. Related methods, apparatus, computer program products, and computer systems are also described.

Abstract: A digital power supply system provides a supply voltage to semiconductor circuits. The power supply system utilizes a pulse width modulator to output a signal into a LC filter that generates a DC supply voltage. The width of the pulses output by the pulse width modulator are defined by an encoder that generates width information in response to a propagation delay detector that measures the propagation delay of a first clock signal when clocked by a second clock signal.

Abstract: The disclosed embodiments relate to a security module and a method of operating a security module. The method may comprise the acts of detecting a second security module, determining whether a key associated with the second security module is available to the first security module, and obtaining the key associated with the second security module if the key associated with the second security module is not available to the first security module. The security module may comprise a detector that is adapted to detect another security module and determine whether one of a plurality of keys is associated with the other security module, and a device that obtains at least one key associated with the other security module if the one of the plurality of keys is not associated with the other security module.

Abstract: A method and apparatus for initializing multiple security modules are provided. The method may comprise the acts of determining if the security module is a controlling security module or a subordinate security module, generating at least one key if the security module is the controlling security module, and receiving at least one key from another security module if the security module is the subordinate security module. The apparatus may comprise a detector that is adapted to determine if the security module is a controlling security module or a subordinate security module, a key generator that generates a key for the security module if the security module is the controlling security module, and a key receiver that receives a key from another security module if the security module is the subordinate security module.

Abstract: A method and apparatus for providing security for a computer system, which includes generating a request for a file. The request is received at a dedicated security processor, where the dedicated security processor may access the file to validate the requested file. Upon determining that the requested file is valid, the dedicated security processor may provide the requested file to another processor.

Abstract: The disclosed embodiments relate to method and apparatus for providing computer security system. The method may include calculating a hash value of an operation at an administrative system. The signed hash of the operation may be created in the administrative system. The signed hash may be received at the managed system. The managed system may validate the signed hash by using a stored reference hash. Upon determining if the signed hash is valid, the managed system may execute the operation that corresponds to the signed hash.

Abstract: In a method for detecting a varying data rate in a data signal, with which data signal a bit is transmitted in the form of a signal edge generated at a particular nominal time, after triggering by an interrupt signal (IS) generated in an analog/digital converter (13), the times of occurrence (TA, TB, TC, TD) of the signal edges are detected and subsequently the edge intervals (T1, T2) determined from the times of occurrence (TA, TB, TC, TD) of the signal edges and subsequently the mean edge interval (Tm) determined from the determined edge intervals (T1, T2). From the mean edge interval (Tm) and a tolerance range of the mean edge interval (Tm) are determined an upper time of occurrence limit (OAZ) and a lower time of occurrence limit (UAZ), within which upper and lower time of occurrence limit a subsequent signal edge must occur in order to be valid for the detection of a current data rate from the mean edge interval (Tm).

Abstract: A digital power supply system provides a supply voltage to semiconductor circuits. The power supply system utilizes a pulse width modulator to output a signal into a LC filter that generates a DC supply voltage. The width of the pulses output by the pulse width modulator are defined by an encoder that generates width information in response to a propagation delay detector that measures the propagation delay of a first clock signal when clocked by a second clock signal.

Abstract: One embodiment of the writing instrument described herein comprises a pen-like device containing three accelerometers and three gyroscopes. Data from these sensors are processed via an Euler transform. Prior to using the writing instrument, the user holds the writing instrument in multiple predefined positions and sensor readings are taken. The sensor readings are mapped to the corresponding predefined positions. In addition, the sensor readings are compared to expected sensor readings to compensate for environmental variations such as altitude or temperature as well as for the possible tilt of a writing surface. The sensor readings are interpolated to map sensor readings other than those at the predefined positions to other writing instrument positions. When the user writes with the writing instrument, sensor outputs are used to track the writing instrument to define strokes made by the user.

Abstract: Sets of genetic markers for specific tumor classes are described, as well as methods of identifying a biological sample based on these markers. Also described are diagnostic, prognostic, and therapeutic screening uses for these markers, as well as oligonucleotide arrays comprising these markers.

Abstract: A flexural pivot assembly which reduces the number of component parts to five and reduces the number of operations in the manufacturing process is disclosed. The component parts include two sleeves, one inner flexure, one outer flexure, and one slotted tubular core that may be coated with a suitable bonding material. The core has a slotted end and an unslotted end and includes two pairs of diametrically opposed flexure slots each having substantially the same length as a side of a flexure so that the interlocked flexures can slide into the slotted end of the tubular core until they abut an end of the flexure slots and, at the same time, be positioned flush with the slotted end. The core further includes a pair of diametrically opposed travel slots.

Abstract: A method and apparatus to precisely track the position of the writing instrument, specifically the writing end, such as the tip, of a pen. One embodiment of the invention described herein includes a writing instrument containing acceleration sensors and angular velocity sensors. Data from these sensors are processed via an Euler transform to determine the strokes made with the writing instrument. Corrections may be made to improve upon the output of the Euler transform. The data describing the strokes may include graphical representations of the strokes actually made with the writing instrument. Data describing the strokes may be stored or processed to accomplish a variety of tasks such as recording information, faxing a message, recording an appointment, or other such tasks.

Abstract: A method and apparatus for sending a facsimile of a message is disclosed. The present invention provides for recording pen strokes that set forth a message and sending the recorded pen strokes as part of a facsimile.

Abstract: One embodiment of the writing instrument described herein comprises a pen-like device containing three accelerometers and three gyroscopes. Data from these sensors are processed via an Euler transform. Prior to using the writing instrument, the user holds the writing instrument in multiple predefined positions and sensor readings are taken. The sensor readings are mapped to the corresponding predefined positions. In addition, the sensor readings are compared to expected sensor readings to compensate for environmental variations such as altitude or temperature as well as for the possible tilt of a writing surface. The sensor readings are interpolated to map sensor readings other than those at the predefined positions to other writing instrument positions. When the user writes with the writing instrument, sensor outputs are used to track the writing instrument to define strokes made by the user.

Abstract: The present invention relates to the use of a gating means in combination with a spontaneous infiltration process to produce a metal matrix composite body. Particularly, a permeable mass of filler material or a preform is spontaneously infiltrated by molten matrix metal to form a metal matrix composite body. A gating means is provided which controls or limits the areal contact between molten matrix metal and the filler material or preform. The use of a gating means provides for control of the amount of matrix metal which can contact the preform or filler material, which may result in less machining of a formed metal matrix composite body compared with a similar metal matrix composite body made without a gating mean. Moreover, the use of a gating means ameliorates the tendency of a formed metal matrix composite body to warp due to the contact between the formed composite body and matrix metal carcass.

Abstract: A face gasket made of a smooth, non-tacky, low durometer, chemically resistant closed cell resin foam is attached onto a goggles frame by injecting the resin into a mold cavity containing a contoured rim portion of the goggles frame. The contoured rim portion is intersected by multiple sprue openings that permit the pressurized resin to flow through the goggles frame and around the contoured rim during molding. The contoured rim portion is embedded within the molded gasket and sprue slugs extend through and fill the openings. The sprue slugs are integrally formed with the main body of the face gasket, thereby defining attachment links that permanently connect the face gasket in splash sealing engagement around the contoured rim and along internal and external sidewall surfaces of the goggles frame.

Abstract: The method includes locating a target on a printed circuit board laminate having a circuit pattern etched thereon and utilizing the target to locate the laminate in a punching device. Preferably two such targets are employed and the laminate is adjusted in the X and Y directions as well as rotationally to bring the target into prescribed relationship with reference markings whereby to locate the holes precisely in the laminate whereby to facilitate stacking of the same. In related apparatus two television cameras are employed to operate with two targets to feed data into a microprocessor which generates signals to cause an alignment of the laminate to be punched. With respect to punching mechanisms special techniques are employed to locate the centers of the targets so that these centers can be aligned with cross hairs to take into account the deviations possible in the configurations of the targets.

Abstract: Method and apparatus for effecting operations, such as punching holes in sheets of material at precise locations thereon. Each sheet has a reference marking thereon and is placed on a receiver one by one and is held in fixed position on the receiver. A T.V. camera views each sheet to detect the reference marking thereon and a visual display of the marking is produced on a T.V. monitor. Also produced on the monitor is a cross-hair grating with a coincident shaded box. The cross-hair grating is first aligned with a marking reference on a master sheet to establish a fixed relation between the cross-hair and the marking reference on the master sheet and thereby between the cross-hair and the operating system, for example, the punches for punching holes in the sheets. The master sheet is removed and the sheets to be punched are placed one by one on the receiver which is moved to align the reference marking on each sheet, as viewed on the monitor with the cross-hair grating thereon.

Abstract: Apparatus for stacking a plurality of laminate layers in registered superposed relation to enable the layers to be joined to form a composite board comprising a table having a surface on which a plurality of laminate layers can be successively stacked in aligned superposed relation on pins slidably received in respective apertures in the table. The pins rest on support members which are carried on a lower support table mounted beneath the surface of the table on which the laminate layers are stacked. The lower support table is raised relative to the stack of laminate layers after successive laminate layers have been placed on the pins so that a given projection of the pins from the laminate layers will be obtained.