Patents by Inventor Michael Anthony Dotlich

Michael Anthony Dotlich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formation and anion-exchange of crystalline echinocandin ammonium salts
    Patent number: 6590073
    Abstract: A method is described for forming a crystalline Echinocandin nucleus salt from its mixed broth and/or partially purified process streams by the steps of nanofiltration to form a concentrate, addition of an aldehyde derivatizing agent which interacts with an aldehyde impurity, addition of an acid/metal salt to form a solubilized echinocandin nucleus salt having the desired anion, and subsequent cooling of the mixture to crystallize the salt.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: July 8, 2003
    Assignee: Eli Lilly and Company
    Inventors: Brian Weston Dalder, Michael Anthony Dotlich, Neil John Kallman, Samuel Dean Larsen, Sharon Van Den Berghe Snorek, Jeffrey Thomas Vicenzi
  • Formation and anion-exchange of crystalline echinocandin ammonium salts
    Publication number: 20020161176
    Abstract: A method is described for forming a crystalline Echinocandin nucleus salt from its mixed broth and/or partially purified process streams by the steps of nano-filtration to form a concentrate, addition of an aldehyde derivatizing agent which interacts with an aldehyde impurity, addition of an acid/metal salt to form a solubilized echinocandin nucleus salt having the desired anion, and subsequent cooling of the mixture to crystallize the salt.
    Type: Application
    Filed: August 30, 2001
    Publication date: October 31, 2002
    Inventors: Brian Weston Dalder, Michael Anthony Dotlich, Neil John Kallman, Samuel Dean Larsen, Sharon Van Den Berghe Snorek, Jeffrey Thomas Vicenzi