Patents by Inventor Michael Anthony Forth

Michael Anthony Forth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorph of mutilin
    Patent number: 8334303
    Abstract: Disclosed is a novel polymorphic form of the compound of formula (I) also known as mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate, a process for the preparation of the polymorphic form, pharmaceutical compositions comprising the polymorphic form, and the use of the polymorphic form in medicine, particularly in antibacterial therapy.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: December 18, 2012
    Assignee: Glazo Group Limited
    Inventors: Alan Collier, Michael Anthony Forth, Darren Hewitt, Paul Oxley
  • Process, salts, composition and use
    Patent number: 8207191
    Abstract: The present invention provides a novel process for preparing pleuromutilin derivatives, novel salts of mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate or solvates thereof, novel pharmaceutical compositions or formulations for topical administration comprising mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate or a pharmaceutically acceptable salt or solvate thereof and their use in medical therapy, particularly antibacterial therapy.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: June 26, 2012
    Assignee: Glaxo Group Limited
    Inventors: Michael Anthony Forth, Susan ShuMei Hu Kopelman, Francis Xavier Muller, Francis Dominic Sanderson
  • NOVEL PROCESS, SALTS, COMPOSITION AND USE
    Publication number: 20110144151
    Abstract: The present invention provides a novel process for preparing pleuromutilin derivatives, novel salts of mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate or solvates thereof, novel pharmaceutical compositions or formulations for topical administration comprising mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate or a pharmaceutically acceptable salt or solvate thereof and their use in medical therapy, particularly antibacterial therapy.
    Type: Application
    Filed: December 23, 2010
    Publication date: June 16, 2011
    Inventors: Gary Francis Breen, Michael Anthony Forth, Susan ShuMei Hu Kopelman, Francis Xavier Muller, Francis Dominic Sanderson
  • Process salts compositions and use
    Patent number: 7875630
    Abstract: The present invention provides a novel process for preparing pleuromutilin derivatives, novel salts of mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate or solvates thereof, novel pharmaceutical compositions or formulations for topical administration comprising mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate or a pharmaceutically acceptable salt or solvate thereof and their use in medical therapy, particularly antibacterial therapy.
    Type: Grant
    Filed: August 30, 2004
    Date of Patent: January 25, 2011
    Assignee: Glaxo Group Limited
    Inventors: Gary Francis Breen, Michael Anthony Forth, Susan ShuMei Hu Kopelman, Francis Xavier Muller, Francis Dominic Sanderson
  • Novel Polymorph of Mutilin
    Publication number: 20080161342
    Abstract: Disclosed is a novel polymorphic form of the compound of formula (I) also known as mutilin 14-(exo-8-methyl-8-azabicyclo [3.2.1]oct-3-ylsulfanyl)-acetate, a process for the preparation of the polymorphic form, pharmaceutical compositions comprising the polymorphic form, and the use of the polymorphic form in medicine, particularly in antibacterial therapy.
    Type: Application
    Filed: February 28, 2006
    Publication date: July 3, 2008
    Inventors: Alan Collier, Michael Anthony Forth, Darren Hewitt, Paul Oxley
  • Processes and intermediates for the preparation of 2-substituted benzaldehydes
    Patent number: 5659084
    Abstract: Processes for preparing 2-substituted benzaldehydes of general formula (I), wherein: R.sub.1 is CH.sub.2 CH.sub.2 --(L.sub.1).sub.p --(CH.sub.2).sub.q --(L.sub.2).sub.r --CH.sub.2 --(T).sub.2 --Z; L.sub.1 and L.sub.2 are independently CH.sub.2 CH.sub.2, CH.dbd.CH or C.tbd.C; q is 0 to 8; p, r and s are independently 0 or 1; T is O, S, CH.sub.2, CH.dbd.CH, C.tbd.C; and Z is C.sub.1-4 alkyl, ethynyl, trifluoromethyl, isopropenyl, furanyl, thienyl, cyclohexyl or phenyl optionally mono substituted with CF.sub.3, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, methylthio, or trifluoromethylthio; and R.sub.2 and A are independently H, CF.sub.3, C.sub.1-4 alkyl, F, Cl, Br or I; are useful for preparing pharmaceutically active compounds.
    Type: Grant
    Filed: December 7, 1994
    Date of Patent: August 19, 1997
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Kerry Joseph Gombatz, Michael Anthony Forth, Jerome Francis Hayes, Michael Barry Mitchell, Stephen Alexander Smith