Patents by Inventor Michael Anthony Letavic

Michael Anthony Letavic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazolo-pyridines as anti-inflammatory compounds
    Patent number: 7321040
    Abstract: The present invention relates to novel triazolo-pyridines of the formula wherein X is >CH2, >NH, sulfur, >S?O, >SO2 or oxygen; wherein said >CH2 and >NH may optionally be substituted with a suitable substituent; R1 is selected from the group consisting of hydrogen, (C1-C6)alkyl and other suitable substituents; R2 is selected from the group consisting of hydrogen, (C1-C6)alkyl and other suitable substituents; s is an integer from 0-4; R3 is R4, R5—(NR6)—, R5—S—, R5—(S?O)—, R5—(SO2)—, R5—SO2—NR6—, R5—(NR6)—SO2—, R5—O—, R5—(C?O)—, R5—(NR6)—(C?O)—, R5—(C?O)—NR6—, R5—O—(C?O)—, R5—(C?O)—O—, R5—CR7?CR8— or R5—C?C—; such that the molecular weight of R3 is less than 500 AMU, preferably less than 250 AMU; R4, R5 and R6 are each selected from the group consisting of hydrogen, (C1-C6)alkyl and other suitable substituents; or a pharmaceutically acceptable salt thereof; to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use.
    Type: Grant
    Filed: February 11, 2004
    Date of Patent: January 22, 2008
    Assignee: Pfizer Inc.
    Inventors: John Frederick Braganza, Michael Anthony Letavic, Kim F. McClure
  • 4?-substituted-9-deoxo-9a-aza-9a-homoerythromycin A derivatives
    Patent number: 6936592
    Abstract: The invention relates to a method of preparing compounds of the formula and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are antibacterial agents that may be used to treat various bacterial and protozoa infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial protozoa infections by administering the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1 and to intermediates useful in such preparation.
    Type: Grant
    Filed: March 26, 2004
    Date of Patent: August 30, 2005
    Assignee: Pfizer, Inc.
    Inventors: Brian Scott Bronk, Michael Anthony Letavic
  • 4"-substituted-9-deoxo-9A-AZA-9A-homoerythromycin a derivatives
    Publication number: 20040180842
    Abstract: The invention relates to a method of preparing compounds of the formula 1
    Type: Application
    Filed: March 26, 2004
    Publication date: September 16, 2004
    Applicant: Pfizer Inc
    Inventors: Brian Scott Bronk, Michael Anthony Letavic, Takushi Kaneko, Bingwei Vera Yang, Edward Alan Glazer, Hengmiao Cheng
  • 4?-substituted-9-deoxo-9a-aza-9a homoerythromycin a derivative
    Patent number: 6777393
    Abstract: The invention relates to a method of preparing compounds of the formula and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are antibacterial agents that may be used to treat various bacterial and protozoa infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial protozoa infections by administering the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1 and to intermediates useful in such preparation.
    Type: Grant
    Filed: October 18, 2002
    Date of Patent: August 17, 2004
    Assignee: Pfizer Inc.
    Inventors: Brian Scott Bronk, Michael Anthony Letavic, Takushi Kaneko, Bingwei Vera Yang, Edward Alan Glazer, Hengmiao Cheng
  • 4''-Substituted-9-deoxo-9a-aza-9a homoerythromycin a derivative
    Publication number: 20040023896
    Abstract: The invention relates to a method of preparing compounds of the formula 1
    Type: Application
    Filed: October 18, 2002
    Publication date: February 5, 2004
    Applicant: Pfizer Inc.
    Inventors: Brian Scott Bronk, Michael Anthony Letavic, Takushi Kaneko, Bingwei Vera Yang, Edward Alan Glazer, Hengmiao Cheng
  • C-4?-substituted macrolide derivatives
    Patent number: 6576749
    Abstract: Compounds are of the formula: and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are potent antibacterial agents that can be used to treat various bacterial infections and disorders related to such infections. The invention also relates to pharmaceutical compositions including the compounds of formula 1 and to methods of treating bacterial infections by administering the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1 and to intermediates useful in such preparation.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: June 10, 2003
    Assignee: Pfizer Inc.
    Inventors: Brian Scott Bronk, Takushi Kaneko, Michael Anthony Letavic, Hengmaio Cheng, Edward Alan Glazer, Bingwei Vera Yang
  • C-4"-substituted macrolide derivatives
    Publication number: 20020156026
    Abstract: This invention relates to compounds of formula (1) and to pharmaceutically acceptable salts thereof. The compounds of formula (1) are potent antibacterial agents that may be used to treat various bacterial infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula (1) and to methods of treating bacterial infections by administering the compounds of formula (1). The invention also relates to methods of preparing the compounds of formula (1) and to intermediates useful in such preparation.
    Type: Application
    Filed: February 26, 2002
    Publication date: October 24, 2002
    Inventors: Brain Scott Bronk, Takushi Kaneko, Michael Anthony Letavic, Hengmaio Cheng, Edward Alan Glazer, Bingwei Vera Yang
  • 4?-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives
    Patent number: 6420536
    Abstract: The invention relates to a method of preparing compounds of the formula and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are antibacterial agents that may be used to treat various bacterial and protozoa infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial protozoa infections by administering the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1 and to intermediates useful in such preparation.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: July 16, 2002
    Assignee: Pfizer Inc
    Inventors: Brian Scott Bronk, Michael Anthony Letavic, Takushi Kaneko, Bingwei Vera Yang, Edward Alan Glazer, Hengmiao Cheng
  • C-4?-substituted macrolide derivatives
    Patent number: 6407074
    Abstract: This invention relates to compounds of the formula and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are potent antibacterial agents that may be used to treat various bacterial infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial infections by administering the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1 and to intermediates useful in such preparation.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: June 18, 2002
    Assignee: Pfizer Inc
    Inventors: Brian Scott Bronk, Takushi Kaneko, Michael Anthony Letavic, Hengmaio Cheng, Edward Alan Glazer, Bingwei Vera Yang
  • 4"-substituted-9-deoxo-9A-AZA-9A-homoerythromycin a derivatives
    Publication number: 20020061858
    Abstract: The invention relates to compounds of the formula 1
    Type: Application
    Filed: November 21, 2001
    Publication date: May 23, 2002
    Inventors: Brian Scott Bronk, Michael Anthony Letavic, Takushi Kaneko, Bingwei Vera Yang, Edward Alan Glazer, Hengmiao Cheng