Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: In one aspect, a system includes a movable barrier operator configured to open and close a movable barrier; at least one ultra-wideband device associated with the movable barrier operator and electrically configured to receive ultra-wideband radio frequency signals; and a processor operatively connected to the at least one ultra-wideband device and configured to use the ultra-wideband radio signals to determine a status of the movable barrier.

Abstract: A reversible toy includes a body having a first surface and a second surface opposite the first surface. The body may be reversible between a first configuration and a second configuration to alternatingly present the first and second surfaces as an outer body surface defining an exterior of the body. In this regard, the other of the first and second surfaces may alternatingly define a stored body surface defining an interior cavity within the body. The reversible toy may further include an appendage attached to the body at the first surface and comprising a coupling feature. The coupling feature may be configured to couple the reversible toy to an object at the appendage.

Abstract: Very high refractive index (n>2.2) lightguide substrates enable the production of 70° field of view eyepieces with all three color primaries in a single eyepiece layer. Disclosed herein are viewing optics assembly architectures that make use of such eyepieces to reduce size and cost, simplifying manufacturing and assembly, and better-accommodating novel microdisplay designs.

Abstract: Intra-cardiac voltage data display systems display a plurality of data sets derived at least from intra-cardiac voltage data sampled by an electrode. In some embodiments, at least some of the data sets are derived from a portion of the intra-cardiac voltage data that excludes an excludable portion of the intra-cardiac voltage data having a relationship with an occurrence of a particular cardiac event to facilitate identification of the existence of a transmural lesion in tissue adjacent the electrode. In some embodiments, the particular cardiac event is the occurrence of an R wave in the cardiac cycle, and the excludable portion is a V wave in the cardiac cycle.

Abstract: Systems and methods of aircraft thrust management are provided. For example, a propulsion system for an aircraft comprises a fuel cell assembly comprising a fuel cell, a turbomachine, and a controller comprising memory and one or more processors. The memory stores instructions that, when executed by the one or more processors, cause the propulsion system to perform operations including receiving data indicative of a propulsion system thrust discrepancy and modifying an output of the fuel cell in response to receiving data indicative of the propulsion system thrust discrepancy. Modifying the fuel cell output may include modifying output products, an electrical power output, or both of the fuel cell to balance the thrust provided by the propulsion system.

Abstract: A system and method that measures the code non-linearity of a phase mixer (PMIX) during active operation of a clock and data recovery (CDR) circuitry. The PMIX circuitry generates a clock signal based on the PMIX codes. The PMIX circuitry receives a plurality of codes and based on the code value, adjusts the phase of the PMIX output clock signal. A number of times each of the plurality of PMIX codes occurs within a respective time period is determined. Non-linearity values are determined based on the number of times. The non-linearity values are stored in a memory.

Abstract: A bottom bracket assembly with interconnected axle and crank arms. Each end of the axle has a plurality of angled surfaces and a recess formed with a depth through at least the axle perimeter and at least partially around the perimeter of the axle. Each crank arm has a slot formed a distance along the length such that the end of the crank arm is separated into two deflectable jaws. A bore is formed orthogonal to the slot and a fastener is installed in the bore, wherein the fastener has a length to span the slot in the crank arm to engage both deflectable jaws. The fastener has a shank radius that extends to a depth of the recess. Removal of the crank arm from the axle end is opposed when the fastener is in the bore.

Abstract: A component connector is positioned in downhole tool. The downhole component includes a bulkhead and a receiver positioned in a housing. The component connector includes a contact member positioned in the bulkhead and a connector member in a receiver of the downhole tool. The contact member has an elongate body with a coupling end and a contact end. The connector member has another elongate body having a coupler end and a receptacle end. The connector member has an engager positioned about an outer surface of the connector member to provide selective engagement with the receiver. The coupling end of the contact member and the coupler end of the connector member are connected to electronics in the housing and wherein the receptacle end of the contact member is shaped to electrically receive the contact end of the contact member whereby electronics in adjacent components of the downhole tool are electrically coupled.

Abstract: Computer-implemented methods and systems for connecting users including sponsored users to different types of care suppliers through a platform coupled over a network to one or more remote devices accessed by users are described. A method includes enabling a sponsored user to book a type of care using a mobile application on a remote computing device communicatively coupled to the platform. The method further includes receiving a request from the sponsored user identifying a desired care type; determining, by a platform, a set of candidate care providers that satisfy matching criteria for the received user request; enabling the sponsored user to select through the mobile application a care provider from the determined set of candidate care providers; and enabling the sponsored user to remit payment to the care provider upon completion of an associated care transaction.

Abstract: A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.

Abstract: Computing resources are managed in a computing network comprising a computing service provider and an edge computing network. The edge computing network receives an indication of a disconnection of communications between the computing service provider and the edge computing network. In response to the indication, the edge computing network initiates an autonomous mode at the edge computing network. The edge computing network is configured to continue providing computing and network services at the edge computing network while the edge computing network is operating in the autonomous mode.

Abstract: A propulsion system is provided including: a gas turbine engine including a combustion section having a combustor; and a modular fuel cell assembly. The modular fuel cell assembly includes: a first fuel cell string comprising a first processing unit and a first fuel cell stack, the first fuel cell stack comprising a first fuel cell defining an outlet configured to provide output products from the first fuel cell to the combustor; and a second fuel cell string comprising a second processing unit and a second fuel cell stack, the second fuel cell stack comprising a second fuel cell defining an outlet configured to provide output products from the second fuel cell to the combustor.

Abstract: Head mounted display systems configured to project light to an eye of a user to display augmented reality image content in a vision field of the user are disclosed. In embodiments, the system includes a frame configured to be supported on a head of the user, an image projector configured to project images into the user's eye, a camera coupled to the frame, a waveguide optically coupled to the camera, an optical coupling optical element me, an out-coupling element configured to direct light emitted from the waveguide to the camera, and a first light source configured to direct light to the user's eye through the waveguide. Electronics control the camera to capture images periodically and farther control the first light source to pulse in time with the camera such that light emitted by the light source has a reduced intensity when the camera is not capturing images.

Abstract: A device and system for purifying a fluid is provided. The system includes a tank having an interior space and a media container disposed within the interior space. A valve is provided that cooperates with an element within the interior, the valve being movable between an open and a closed position. The valve being biased to the open position when the element is not positioned within the interior space, wherein the interior space is fluidly coupled to the atmosphere in the open position. The valve further being configured to move to a closed position when the element is positioned within the interior space.

Abstract: A system for delivering content to a wireless handset is described. The system comprises a beacon and a wireless handset communicatively coupled to a network. The wireless handset receives a signal from the beacon. A user profile associated with the wireless handset comprises at least one user attribute. The system further comprises a content administration interface configured to store an association between a content item and a user attribute. The system further comprises a content delivery module that retrieves content item(s) associated with a user attribute. The content delivery module transmits at least one retrieved content item to the wireless handset via the network. A handset content interface displays the at least one transmitted content item on the wireless handset.

Abstract: Transparently providing a virtualization feature to an unenlightened guest operating system (OS). A guest partition, corresponding to a virtual machine, is divided into a first guest privilege context and a second guest privilege context. A compatibility component executes within the first guest privilege context, while a guest OS executes within the second guest privilege context. The compatibility component is configured to intercept input/output (I/O) operations associated with the guest operating OS. Based on the compatibility component intercepting an I/O operation associated with the guest OS, the compatibility component processes the I/O operation using a virtualization feature that is unsupported by the guest OS. Examples of the virtualization feature include accelerated access to a hardware device and virtual machine guest confidentiality.

Abstract: The present invention relates to solid forms of (5S)-cyclopropyl-5-[3-[(3S)-4-(3,5-difluorophenyl)-3-methyl-piperazin-1-yl]-3 -oxo-propyl]imidazolidine-2,4-dione and to pharmaceutical preparations comprising them and methods of their manufacture, as well as the use of said solid forms or preparations for the prophylaxis and/or treatment of inflammatory conditions, muscular disease, fibrotic diseases, viral infection, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis, especially osteoarthritis.

Abstract: The present invention provides a moisture reduction roller conveyor system (100, 200, 301) and method comprising a continuous carry belt (105, 205, 308) to carry a bulk material and an oscillatory motion assembly (110, 210, 320) operatively connected and configured to induce oscillatory motion of the belt that is transmitted to the bulk material. The oscillatory motion assembly (110) is operatively connected to the frame to induce the oscillatory motion. Alternatively, the oscillatory motion assembly has idler rollers (210a, 210b, 210c) that are offset or eccentric to one another to induce the oscillatory motion. A different oscillatory motion assembly comprises a carriage body (325) for supporting the belt (308) and wheels (340, 345) for engaging a rail track (302). The wheels (340, 345) are configured to induce the oscillatory motion, preferably by periodically lifting one end (360) of the carriage body from the rail track as the carriage moves.

Abstract: An iron-air battery including an iron electrode in contact with an anode current collector, wherein the iron electrode includes a plurality of channels; an oxygen reduction reaction electrode having a first surface facing the plurality of channels and an opposing second surface in contact with air; an oxygen evolution reaction electrode interdigitated with the plurality of channels of the iron electrode, wherein at least a portion of the oxygen evolution reaction electrode is disposed within the plurality of channels in a direction perpendicular to a plane of the oxygen reduction reaction electrode; and an electrolyte in contact with the iron electrode, the first surface of the oxygen reduction reaction electrode, the plurality of channels, and the oxygen evolution reaction electrode.