Abstract: Provided are methods for making yolk sac like hematopoietic progenitors by specifying a KDR+CD235a/b+ mesoderm cells capable of giving rise to T lymphoid lineage cells or cells differentiated therefrom. The method involves contacting pluripotent stem cells (PSCs) with a mesoderm specifying culture composition comprising a BMPR1/R2 agonist, an FGF receptor agonist and an activin receptor agonist to produce a KDR+CD235a/b+ mesoderm cells; and optionally isolating the KDR+CD235a/b+ mesoderm cells.

Abstract: This invention relates to a beverage insulating sleeve that can hold two portable beverage containers, cold or hot packs and personal belongings around back of neck of user facilitating hands free activities. The sleeve is light weight and highly absorbent.

Abstract: A liquid receptacle and water reservoir in combination with a pet collar is provided by the present invention. The water reservoir is comprised of: a tubular shaped water reservoir provided with a first orifice for filling said reservoir with fluid and a second orifice for dispensing the fluid from said reservoir, a plurality of reflective strips applied to the surface of said water reservoir, a standard choke and harness attachment provided for attaching said water reservoir with the body of an animal, a spigot-type dispensing member provided from said second orifice for assisting the dispensing of the fluid from said water reservoir, and a receptacle connecting the reservoir to said dispensing device.

Abstract: A system, method, and computer program for modifying a model, comprising the steps of reading a model geometry into a constraint solver; generating a set of base values from said constraint solver; applying said set of base values to said model geometry; recalculating said model geometry in response to a plurality of modified values; and regenerating a valid model from said recalculated model geometries and appropriate means and computer-readable instructions.

Abstract: A system, method, and computer program for a finding an intersection for geometrically coincident curves, comprising selecting a curve pair where at least one curve in said curve pair is a parametric curve; determining a curve parameter for each curve in said curve pair; splitting each of said curves into a plurality of candidate segments; recursively subdividing each of said candidate segments into a pair of finalized segments that are sufficiently straight; intersecting an approximation for each of said finalized segments; obtaining a plurality of next parameter values from said intersecting step; and testing for a terminating condition and appropriate means and computer-readable instructions.