Patents by Inventor Michael Axtell

Michael Axtell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for efficient gene silencing in plants
    Patent number: 8143480
    Abstract: This invention relates to methods for knock-down of a target gene in plants, particularly efficient and specific methods for knock-down of a target gene in plants. This invention also relates to methods for silencing endogenous plant genes or plant pathogen genes. It further relates to nucleic acid constructs (DNA, RNA) which comprise a nucleic acid sequence that corresponds to a target gene or fragment thereof flanked by two complementary sites to an smRNA, e.g., a miRNA (one complementary site is on either side of the nucleic acid sequence), resulting in, for example the configuration: complementary site—nucleic acid sequence that corresponds to a target gene—complementary site.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: March 27, 2012
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Michael Axtell, David P. Bartel
  • Compositions and methods for efficient gene silencing in plants
    Publication number: 20090172838
    Abstract: This invention relates to methods for knock-down of a target gene in plants, particularly efficient and specific methods for knock-down of a target gene in plants. This invention also relates to methods for silencing endogenous plant genes or plant pathogen genes. It further relates to nucleic acid constructs (DNA, RNA) which comprise a nucleic acid sequence that corresponds to a target gene or fragment thereof flanked by two complementary sites to an smRNA, e.g., a miRNA (one complementary site is on either side of the nucleic acid sequence), resulting in, for example the configuration: complementary site—nucleic acid sequence that corresponds to a target gene—complementary site.
    Type: Application
    Filed: October 19, 2007
    Publication date: July 2, 2009
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Michael Axtell, David P. Bartel