Patents by Inventor Michael B. Duncan

Michael B. Duncan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purified and isolated heparan sulfate 3--sulfotransferase isoform 5 nucleic acids and polypeptides and therapeutic and screening methods using same
    Patent number: 7531338
    Abstract: 3-OST-5 proteins, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to 3-OST-5 homologs, and methods of producing the same, are also disclosed. 3OST-5 gene products have biological activity in specific heparan sulfate 3-O-sulfotransferase reactions. These reactions provide unique modified heparan sulfate. Thus, therapeutic methods involving this activity are also disclosed.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: May 12, 2009
    Assignees: The University of North Carolina at Chapel Hill, The Board of Trustees of the University of Illinois
    Inventors: Jian Liu, Guoqing Xia, Jinghua Chen, Michael B. Duncan, Deepak Shukla, Vaibhav Tiwari, Anders Malmstrom