Patents by Inventor Michael B. Holmes
Michael B. Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240374149Abstract: In accordance with some embodiments, systems, methods, and media for estimating compensatory reserve and predicting hemodynamic decompensation using physiological data are provided. In some embodiments, a system for estimating compensatory reserve is provided, the system comprising: a processor programmed to: receive a blood pressure waveform of a subject; generate a first sample of the blood pressure waveform with a first duration; provide the sample as input to a trained CNN that was trained using samples of the first duration from blood pressure waveforms recorded from subjects while decreasing the subject's central blood volume, each sample being associated with a compensatory reserve metric; receive, from the trained CNN, a first compensatory reserve metric based on the first sample; and cause information indicative of remaining compensatory reserve to be presented.Type: ApplicationFiled: July 23, 2024Publication date: November 14, 2024Inventors: Robert W. Techentin, Timothy B. Curry, Michael J. Joyner, David R. Holmes, III, Clifton R. Haider, Christopher L. Felton, Barry K. Gilbert, Charlotte Sue Van Dorn, William A. Carey, Victor A. Convertino
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Publication number: 20240358552Abstract: A mobile wound cover, comprising a skin adhesion rim having a skin adhesion layer and an oppositely disposed rim adhesion layer, the skin adhesion rim having a first aperture therein a protective rim having a skin surface and a cover surface, the skin surface arranged to secure to the skin adhesion layer of the skin adhesion rim, the protective rim having a second aperture therein, and a cover, the cover arranged to removably engage the cover surface of the protective rim, the cover further including a removable securement means arranged to removably secure the cover to the cover surface of the protective rim, the securement means disposed a distal surface of the cover, the cover being at least semi-transparent.Type: ApplicationFiled: April 26, 2024Publication date: October 31, 2024Inventors: Dennis R. Tollini, Michael D. Tollini, Randell B. Holmes, Gary Kaufmann, Thomas P Stewart
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Patent number: 12076120Abstract: In accordance with some embodiments, systems, methods, and media for estimating compensatory reserve and predicting hemodynamic decompensation using physiological data are provided. In some embodiments, a system for estimating compensatory reserve is provided, the system comprising: a processor programmed to: receive a blood pressure waveform of a subject; generate a first sample of the blood pressure waveform with a first duration; provide the sample as input to a trained CNN that was trained using samples of the first duration from blood pressure waveforms recorded from subjects while decreasing the subject's central blood volume, each sample being associated with a compensatory reserve metric; receive, from the trained CNN, a first compensatory reserve metric based on the first sample; and cause information indicative of remaining compensatory reserve to be presented.Type: GrantFiled: July 21, 2020Date of Patent: September 3, 2024Assignees: Mayo Foundation for Medical Education and Research, The Government of the United States, as Represented by the Secretary of the ArmyInventors: Robert W. Techentin, Timothy B. Curry, Michael J. Joyner, Clifton R. Haider, David R. Holmes, III, Christopher L. Felton, Barry K. Gilbert, Charlotte Sue Van Dorn, William A. Carey, Victor A. Convertino
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Publication number: 20240165351Abstract: The present technology is directed to systems and methods for measuring patient lung pressure in a patient during pressure-controlled or volume-controlled ventilation. For example, the present technology includes operating a ventilator blower at a first speed during an inspiratory phase of a breath to direct gas from the ventilator to the patient along a flow path, and, after the inspiratory phase and before an expiratory phase of the breath, operating the blower at a second speed less than the first speed to achieve a zero-flow state in the flow path during which gas neither flows into nor out of the patient's lungs. During the zero-flow state, the pressure in the flow path is equal or at least approximately equal to the patient lung pressure. Accordingly, pressure can be measured at any position along the flow path during the zero-flow state to determine patient lung pressure.Type: ApplicationFiled: April 14, 2022Publication date: May 23, 2024Inventors: Joseph Cipollone, Samir Ahmad, Michael B. Holmes, Jason Sesmundo
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Publication number: 20220193354Abstract: The present technology is directed to ventilator systems that can provide both ventilation therapy and oxygen therapy. The systems described herein may include a ventilation assembly that can provide inspiratory gas to a patient circuit and an oxygen assembly that can provide pulses of oxygen to an oxygen delivery circuit. In some embodiments, the oxygen delivery circuit is distinct from the patient circuit. For example, the patient circuit can include a corrugated conduit coupled a ventilation mask, and the oxygen delivery circuit can include a nasal cannula. The ventilation mask can be positioned over the nasal cannula so that the patient can receive both the inspiratory gases and the pulses of oxygen.Type: ApplicationFiled: December 21, 2021Publication date: June 23, 2022Inventors: Joseph Cipollone, Andrew R. Chapman, Luke Kobler Johnson, Samir S. Ahmad, Michael B. Holmes, Christopher T. Kiple
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Publication number: 20220148701Abstract: The present technology is directed to respiratory therapy data management systems, device, and methods. The systems can collect, store, monitor, report, and/or analyze patient treatment data associated with patient use of one or more respiratory therapy devices. The patient treatment data can include therapy data related to the use of multiple respiratory therapies, such as ventilation, oxygen, cough-assistance, suction, and nebulization. The patient treatment data may be collected from a plurality of respiratory devices associated with a particular patient, or from a single respiratory device associated with a particular patient. The system can generate customizable reports detailing the patient treatment data. The reports can summarize patient use, illustrate therapy trends, and/or provide therapy recommendations.Type: ApplicationFiled: November 5, 2021Publication date: May 12, 2022Inventors: Joseph Cipollone, Gregory A. McKeag, Michael B. Holmes, Eric A. Harris, Christopher T. Kiple, Chris O. Brooks, Caro Minnick
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Patent number: 7849854Abstract: A ventilator device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: GrantFiled: September 7, 2004Date of Patent: December 14, 2010Assignee: Bird Products CorporationInventors: Douglas F. DeVries, Michael J. Cegielski, Warner V. Graves, Jr., Malcolm R. Williams, Michael B. Holmes
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Publication number: 20090084381Abstract: A ventilator, device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: ApplicationFiled: August 1, 2008Publication date: April 2, 2009Applicant: BIRD PRODUCTS CORPORATIONInventors: Douglas F. DeVRIES, Michael J. Cegielski, Warner V. Graves, JR., Malcolm R. Williams, Michael B. Holmes
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Patent number: 7222623Abstract: A ventilator device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: GrantFiled: December 29, 2004Date of Patent: May 29, 2007Assignee: Birds Products CorporationInventors: Douglas F. DeVries, Michael J. Cegielski, Warner V. Graves, Jr., Malcolm R. Williams, Michael B. Holmes
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Patent number: 6877511Abstract: A ventilator device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: GrantFiled: June 10, 2003Date of Patent: April 12, 2005Assignee: Bird Products CorporationInventors: Douglas F. DeVries, Michael J. Cegielski, Warner V. Graves, Jr., Malcolm R. Williams, Michael B. Holmes
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Publication number: 20030230307Abstract: A ventilator device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: ApplicationFiled: June 10, 2003Publication date: December 18, 2003Inventors: Douglas F. DeVries, Michael J. Cegielski, Warner V. Graves, Malcolm R. Williams, Michael B. Holmes
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Patent number: 6526970Abstract: A ventilator device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: GrantFiled: August 21, 2001Date of Patent: March 4, 2003Inventors: Douglas F. DeVries, Michael J. Cegielski, Warner V. Graves, Jr., Malcolm R. Williams, Michael B. Holmes
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Publication number: 20020005197Abstract: A ventilator device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: ApplicationFiled: August 21, 2001Publication date: January 17, 2002Inventors: Douglas F. DeVries, Michael J. Ceqielski, Warner V. Graves, Malcolm R. Williams, Michael B. Holmes
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Patent number: 6152135Abstract: A portable mechanical ventilator uses a constant-speed compressor compressor and a recirculating bypass circuit. Bypass flow is governed by a spring-biased bypass valve so connected to both the inlet and the outlet of the main flow control valve as to maintain a differential pressure across the flow valve sufficient to operate the ventilator with minimal energy consumption. The flow valve is operated by a microprocessor in accordance with empirically derived lookup tables to both produce the desired air flow and provide a measure of that air flow.Type: GrantFiled: October 23, 1998Date of Patent: November 28, 2000Assignee: Pulmonetic Systems, Inc.Inventors: Douglas F. DeVries, Michael B. Holmes
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Patent number: 5881722Abstract: A ventilator device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: GrantFiled: September 25, 1995Date of Patent: March 16, 1999Assignee: Bird Products CorporationInventors: Douglas F. DeVries, Michael J. Cegielski, Warner V. Graves, Jr., Malcolm R. Williams, Michael B. Holmes
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Patent number: 5868133Abstract: A ventilator device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: GrantFiled: February 3, 1997Date of Patent: February 9, 1999Assignee: Bird Products CorporationInventors: Douglas F. DeVries, Michael J. Cegielski, Warner V. Graves, Jr., Malcolm R. Williams, Michael B. Holmes
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Patent number: 5694926Abstract: A ventilator device and system comprising a rotating compressor, preferably a drag compressor, which, at the beginning of each inspiratory ventilation phase, is accelerated to a sufficient speed to deliver the desired inspiratory gas flow, and is subsequently stopped or decelerated to a basal flow level to permit the expiratory ventilation phase to occur. The ventilator device is small and light weight enough to be utilized in portable applications. The ventilator device is power efficient enough to operate for extended periods of time on internal or external batteries. Also provided is an oxygen blending apparatus which utilizes solenoid valves having specific orifice sizes for blending desired amounts of oxygen into the inspiratory gas flow. Also provided is an exhalation valve having an exhalation flow transducer which incorporates a radio frequency data base to provide an attendant controller with specific calibration information for the exhalation flow transducer.Type: GrantFiled: September 25, 1995Date of Patent: December 9, 1997Assignee: Bird Products CorporationInventors: Douglas F. DeVries, Michael J. Cegielski, Warner V. Graves, Jr., Malcolm R. Williams, Michael B. Holmes